Species: Hu
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, IHC, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Description
Serotonin (5-hydroxytryptamine, or 5-HT) is a monoamine neurotransmitter synthesised in serotonergic neurons in the central nervous system and enterochromaffin cells in the gastrointestinal tract. Serotonin plays an important part in the biochemistry of depression, migraine, bipolar disorder and anxiety. It is also believed to be influential on sexuality and appetite. 5-HT is generally thought not to be released from synaptic terminal buttons in the manner of classical neurotransmission but from serotonergic varacosities into the extra neuronal space. From here it is free to diffuse over a relatively large region of space (>20um) and activate 5-HT receptors located on the dendrites, cell bodies and presynaptic terminals of adjacent neurons. Serotonergic action is terminated primarily via uptake of 5-HT from the synapse. This is through the specific monoamine transporter for 5-HT, 5-HT reuptake transporter, on the presynaptic neuron. The pharmacology of 5-HT is extremely complex, with its actions being mediated by a large and diverse range of 5-HT receptors.
Bioinformatics
| Entrez |
Mouse
Rat
Human
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
3358 |
| Alternate Names |
- 5-HT1C
- 5-HT-1C
- 5-HT-2C
- 5-HT2C5-hydroxytryptamine receptor 1C
- 5-HTR2C
- 5-hydroxytryptamine (serotonin) receptor 2C
- 5-hydroxytryptamine receptor 2C
- HTR1C
- serotonin 5-HT-2C receptor
- Serotonin receptor 2C
|
Research Areas for 5-HT2C
Find related products by research area and learn more about each of the different research areas below.
GPCR
