ZAK Antibody (3D11)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00051776-M02	Applications	Species
Yueh-Min L, Jiro S, Jia-Zun G et al. ZAK? Alleviates Oxidized Low-density Lipoprotein (ox-LDL)-Induced Apoptosis and B-type Natriuretic Peptide (BNP) Upregulation in Cardiomyoblast. Cell Biochem Biophys. 2022-07-01 [PMID: 35776316]
Fu C, Chen M, Tseng Y et al. Fisetin activates Hippo pathway and JNK/ERK/AP-1 signaling to inhibit proliferation and induce apoptosis of human osteosarcoma cells via ZAK overexpression. Environ Toxicol. 2019-05-01 [PMID: 31044527]
Fu C, Tseng Y, Chen M et al. Overexpression of ZAK? in human osteosarcoma cells enhances ZAK? expression, resulting in a synergistic apoptotic effect. Cell Biochem Funct. 2018-04-13 [PMID: 29654619]

Array H00051776-M02

• ZAK Antibodies
• ZAK Lysates
• ZAK Protein