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XPE/DDB2 Antibody [DyLight 594]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
DyLight 594

Order Details

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XPE/DDB2 Antibody [DyLight 594] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the C-terminus of the Human XPE/DDB2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DDB2
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for XPE/DDB2 Antibody [DyLight 594]

  • damage-specific DNA binding protein 2 (48kD)
  • damage-specific DNA binding protein 2, 48kDa
  • Damage-specific DNA-binding protein 2
  • DDB p48 subunit
  • DDB2
  • DDBB
  • DNA damage-binding protein 2
  • FLJ34321
  • UV-damaged DNA-binding protein 2
  • UV-DDB 2
  • UV-DDB2
  • xeroderma pigmentosum group E protein
  • XP5
  • XPE/DDB2

Background

DDB2, also known as DNA damage-binding protein 2, consists of five isoforms of sizes 47.9 kDa, 26.7 kDa, 17.4 kDa, 40.7 kDa, and 26.8 kDa and is involved in repairing DNA damaged by ultraviolet light. Current research is being conducted on disorders and diseases including immunodeficiency, hepatitis, multiple sclerosis, lung cancer, ovarian cancer, skin cancer, and autosomal recessive disease. The protein has been linked to DNA repair and protein stability pathways where it interacts with CUL4A, DDB1, COPS5, ABL1, and E2F1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol DDB2