Reactivity | HuSpecies Glossary |
Applications | ICC/IF, AC |
Concentration | 1.0 mg/ml |
Description | A SLC7A11 antibody blocking peptide. |
Specificity | This peptide is specific for NB300-317 only. |
Protein/Peptide Type | Antibody Blocking Peptide |
Gene | SLC7A11 |
Dilutions |
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Application Notes | This peptide is useful as a blocking peptide for NB300-317. For further blocking peptide related protocol, click here. |
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Publications |
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Storage | Store at -80C. Avoid freeze-thaw cycles. |
Buffer | Peptide dissolved in dH2O. Contains no BSA. |
Preservative | No Preservative |
Concentration | 1.0 mg/ml |
Publication using NB300-317PEP | Applications | Species |
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Pampliega O, Domercq M, Soria FN et al. Increased expression of cystine/glutamate antiporter in multiple sclerosis. J Neuroinflammation. 2011-06-01 [PMID: 21639880] (ICC/IF, Human) | ICC/IF | Human |
Research Areas for xCT Protein (NB300-317PEP)Find related products by research area.
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The effects of ethanol consumption on glutamate production and xCT xCT is a sodium independent glutamate transporter that regulates the exchange of extracellular l-cystine and intracellular l-glutamate across the plasma membrane. This process is critical to glutathione production and protection from subsequent ox... Read full blog post. |
xCT: The Membrane's Gatekeeper xCT is an obligate, electroneutral, membrane-bound anionic transporter responsible for regulating particular amino acid gradients via their transport through plasma membrane. The antiporter xCT superficially resembles an ion channel and preferentially... Read full blog post. |
xCT: Amino Acid Transport and Disorders of the Central Nervous System xCT, encoded by the gene SLC7A11, is a member of the heterodimeric amino acid transporter family. Proteins within this family are linked to one another via a disulphide bond to form heterodimers consisting of one light subunit and one heavy subunit (1... Read full blog post. |
xCT: Friend or Foe? There are two opposing sides to the controversial cysteine/glutamate antiporter. On one hand, it can be viewed a guardian of the cell, protecting it from the damaging oxidative stress that can cause cell death and even cancer. But, conversely, it has ... Read full blog post. |
Glutathione and xCT: Chemoresistance in Tumor Cells Glutathione, called GSH in its reduced form and GSSG or L(-)-Glutathione in its oxidized form, is an endogenous antioxidant found in most cells in the body. Glutathione's functions include detoxifying xenobiotics from the body, assisting in membrane t... Read full blog post. |
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Gene Symbol | SLC7A11 |