VEGFR1/Flt-1 Antibody [Biotin] Summary
Immunogen |
A synthetic peptide made to an internal region of the mouse VEGF Receptor 1 protein (between residues 800-900) [Uniprot: P35969]. There is 87% identity between the immunogen used for this production and the VEGF Receptor 2 protein. |
Localization |
Type 1 membrane protein (isoform Flt1) |
Marker |
Endothelial Cell Marker |
Specificity |
This antibody targets VEGFR-1 but has significant cross-reactivity with the VEGFR-2 protein. |
Predicted Species |
Mouse (100%), Rat (100%), Chicken (94%). Backed by our 100% Guarantee. |
Isotype |
IgG |
Clonality |
Polyclonal |
Host |
Rabbit |
Gene |
FLT1 |
Purity |
Immunogen affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Immunohistochemistry-Paraffin
- Western Blot
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Readout System |
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Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Immunogen affinity purified |
Alternate Names for VEGFR1/Flt-1 Antibody [Biotin]
Background
Receptors for VEGF, VEGFB and PGF have a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability.
VEGF and its high-affinity binding receptors, the tyrosine kinases FLK1 and FLT1, are thought to be important for the development of embryonic vasculature. It has been shown that an alternately spliced form of FLT1 produces a soluble protein, termed sFLT1, which binds vascular endothelial growth factor with high affinity, playing an inhibitory role in angiogenesis.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for VEGFR1/Flt-1 Antibody (NB100-527B) (0)
Secondary Antibodies
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