VDR/NR1I1/Vitamin D Receptor Antibody (2F4)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes the nuclear hormone receptor for vitamin D3. This receptor also functions as a receptor for the secondary bile acid lithocholic acid. The receptor belongs to the family of trans-acting transcriptional regulatory factors and shows sequence similarity to the steroid and thyroid hormone receptors. Downstream targets of this nuclear hormone receptor are principally involved in mineral metabolism though the receptor regulates a variety of other metabolic pathways, such as those involved in the immune response and cancer. Mutations in this gene are associated with type II vitamin D-resistant rickets. A single nucleotide polymorphism in the initiation codon results in an alternate translation start site three codons downstream. Alternative splicing results in multiple transcript variants encoding the same protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IF/IHC, IHC-P.

Showing Publications 1 - 2 of 2.

Publications using H00007421-M02	Applications	Species
Scimeca M, Centofanti F, Celi M et al. Vitamin D Receptor in Muscle Atrophy of Elderly Patients: A Key Element of Osteoporosis-Sarcopenia Connection Aging Dis 2018-12-01 [PMID: 30574409] (IF/IHC, Human)	IF/IHC	Human
Vulpio C, Bossola M, Di Stasio E et al. Histology and immunohistochemistry of the parathyroid glands in renal secondary hyperparathyroidism refractory to vitamin D or cinacalcet therapy. Eur J Endocrinol. 2013-04-29 [PMID: 23520248] (IHC-P, Human)	IHC-P	Human

Array H00007421-M02

• VDR/NR1I1/Vitamin D Receptor Antibodies
• VDR/NR1I1/Vitamin D Receptor ELISA Kit
• VDR/NR1I1/Vitamin D Receptor Lysates
• VDR/NR1I1/Vitamin D Receptor Proteins