VDAC1 Antibody (3A1) Summary
Additional Information |
Recombinant monoclonal antibody expressed in HEK293F cells |
Immunogen |
A synthesized peptide derived from Human VDAC1 [UniProt P21796] |
Isotype |
IgG |
Clonality |
Monoclonal |
Host |
Rabbit |
Gene |
VDAC1 |
Purity |
Affinity purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- ELISA
- Immunohistochemistry 1:50-1:200
- Western Blot 1:500-1:5000
|
Packaging, Storage & Formulations
Storage |
Store at -20 to -70C. Avoid freeze-thaw cycles. |
Buffer |
PBS, pH 7.4, 150mM NaCl and 50% glycerol |
Preservative |
0.02% Sodium Azide |
Purity |
Affinity purified |
Alternate Names for VDAC1 Antibody (3A1)
Background
VDAC1 is an outer membrane mitochondrial protein. The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Secondary Antibodies
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