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VDAC1 Antibody (3A1)

Images

 
Immunohistochemistry: VDAC1 Antibody (3A1) [NBP3-26256] - Image of VDAC1 Antibody (3A1) diluted at 1:73.125 and staining in paraffin-embedded human tonsil tissue performed. After dewaxing and hydration, antigen ...read more
Immunohistochemistry: VDAC1 Antibody (3A1) [NBP3-26256] - Image of VDAC1 Antibody (3A1) diluted at 1:73.125 and staining in paraffin-embedded human tonsil tissue performed. After dewaxing and hydration, antigen ...read more
Western Blot: VDAC1 Antibody (3A1) [NBP3-26256] - Positive Western Blot detected in: Hela whole cell lysate, HepG2 whole cell lysate, 293 whole cell lysate, Jurkat whole cell lysate, HL-60 whole cell lysate, LO2 whole ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clone
3A1
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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VDAC1 Antibody (3A1) Summary

Additional Information
Recombinant monoclonal antibody expressed in HEK293F cells
Immunogen
A synthesized peptide derived from Human VDAC1 [UniProt P21796]
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
VDAC1
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry 1:50-1:200
  • Western Blot 1:500-1:5000

Packaging, Storage & Formulations

Storage
Store at -20 to -70C. Avoid freeze-thaw cycles.
Buffer
PBS, pH 7.4, 150mM NaCl and 50% glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for VDAC1 Antibody (3A1)

  • hVDAC1
  • MGC111064
  • Outer mitochondrial membrane protein porin 1
  • Plasmalemmal porin
  • Porin 31HL
  • Porin 31HM
  • PORIN
  • PORIN-31-HL
  • VDAC
  • VDAC1
  • VDAC-1
  • voltage-dependent anion channel 1
  • voltage-dependent anion-selective channel protein 1

Background

VDAC1 is an outer membrane mitochondrial protein. The VDAC proteins are thought to form aqueous channels, or pores, through which adenine nucleotides cross the outer mitochondrial membrane. VDACs have been implicated in the formation of the mitochondrial permeability transition pore complex in apoptotic cells. This complex, formed by VDAC, adenine nucleotide translocator (ANT), and cyclophilin D (CypD), is thought to allow the mitochondria to undergo metabolic uncoupling and irreversible morphologic changes that ultimately destroy the mitochondria during apoptosis. VDACs are highly expressed in heart, liver and skeletal muscle, where concentrations of mitochondria are at their highest.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol VDAC1