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Vanilloid R1/TRPV1 Antibody

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Vanilloid R1/TRPV1 was detected in perfusion fixed frozen sections of rat dorsal root ganglion using 15 µg/mL Goat Anti-Rat Vanilloid R1/TRPV1 Antigen Affinity-purified Polyclonal Antibody (Catalog ...read more
Vanilloid R1/TRPV1 was detected in perfusion fixed frozen sections of rat brain using Rat Vanilloid R1/TRPV1 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3066) at 15 µg/mL overnight at 4 °C. Tissue was ...read more

Product Details

Summary
Reactivity RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price
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Vanilloid R1/TRPV1 Antibody Summary

Immunogen
KLH-coupled rat Vanilloid R1/TRPV1 synthetic peptide
RASLDSEESESPPQENSC
Accession # O35433
Specificity
Detects rat Vanilloid R1/TRPV1 in immunohistochemistry.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TRPV1
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 5-15 ug/mL
Publications
Read Publications using
AF3066 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Vanilloid R1/TRPV1 Antibody

  • Capsaicin Receptor
  • Osm-9-like TRP channel 1
  • OTRPC1
  • transient receptor potential cation channel subfamily V member 1
  • transient receptor potential cation channel, subfamily V, member 1
  • transient receptor potential vanilloid 1a
  • transient receptor potential vanilloid 1b
  • TRPV1
  • Vanilloid R1
  • Vanilloid receptor 1
  • vanilloid receptor subtype 1
  • VanilloidR1
  • VR1
  • VR1DKFZp434K0220

Background

VR1, also known as TRPV1 (Transient Receptor Potential Vanilloid 1) and capsaicin receptor, is a 115 kDa integral membrane ion channel that has six transmembrane domains and contains intracellular N-and C-termini. It contributes to normal pain and temperature sensation and also has a “sensory-effector” function. By alternative splicing, at least three VR1 isoforms are known. The sequence of residues 4-21 of rat VR1 is 78% and 28% identical to that of mouse and human VR1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vanilloid R1/TRPV1 Antibody (AF3066)(8)

We have publications tested in 1 confirmed species: Rat.

We have publications tested in 2 applications: IHC, IHC-Fr.


Filter By Application
IHC
(3)
IHC-Fr
(1)
All Applications
Filter By Species
Rat
(4)
All Species
Showing Publications 1 - 8 of 8.
Publications using AF3066 Applications Species
Su Bin An, Yi Sul Cho, Sook Kyung Park, Yun Sook Kim, Yong Chul Bae Synaptic connectivity of the TRPV1-positive trigeminal afferents in the rat lateral parabrachial nucleus Frontiers in Cellular Neuroscience 3/30/2023 [PMID: 37066077]
T Yajima, T Sato, H Hosokawa, T Kondo, H Ichikawa Transient receptor potential melastatin-7 in the rat dorsal root ganglion Journal of chemical neuroanatomy, 2022-09-17;125(0):102163. 2022-09-17 [PMID: 36122679] (IHC, Rat) IHC Rat
NJ Yang, J Isensee, DV Neel, AU Quadros, HB Zhang, J Lauzadis, SM Liu, S Shiers, A Belu, S Palan, S Marlin, J Maignel, A Kennedy-Cu, VS Tong, M Moayeri, P Röderer, A Nitzsche, M Lu, BL Pentelute, O Brüstle, V Tripathi, KA Foster, TJ Price, RJ Collier, SH Leppla, M Puopolo, BP Bean, TM Cunha, T Hucho, IM Chiu Anthrax toxins regulate pain signaling and can deliver molecular cargoes into ANTXR2+ DRG sensory neurons Nature Neuroscience, 2021-12-20;0(0):. 12/20/2021 [PMID: 34931070]
Amanda Ferreira Neves, Felipe Hertzing Farias, Silviane Fernandes de Magalhães, Dionéia Araldi, Marco Pagliusi, Claudia Herrera Tambeli et al. Peripheral Inflammatory Hyperalgesia Depends on P2X7 Receptors in Satellite Glial Cells Frontiers in Physiology 5/25/2020 [PMID: 32523543]
T Yajima, T Sato, K Shimazaki, H Ichikawa Transient receptor potential melastatin-3 in the rat sensory ganglia of the trigeminal, glossopharyngeal and vagus nerves J. Chem. Neuroanat., 2019-01-10;96(0):116-125. 2019-01-10 [PMID: 30639448] (IHC, Rat) IHC Rat
Mohd ISa IL, Abbah Sa, Kilcoyne M et al. Implantation of hyaluronic acid hydrogel prevents the pain phenotype in a rat model of intervertebral disc injury. Sci Adv 4/1/2018 [PMID: 29632893]
J Havelin, I Imbert, D Sukhtankar, B Remeniuk, I Pelletier, J Gentry, A Okun, T Tiutan, F Porreca, T King Mediation of movement-induced breakthrough cancer pain by IB4 binding nociceptors in rats J. Neurosci., 2017-04-24;0(0):. 2017-04-24 [PMID: 28438966] (IHC, Rat) IHC Rat
Isensee J, Wenzel C, Buschow R, Weissmann R, Kuss A, Hucho T Subgroup-elimination transcriptomics identifies signaling proteins that define subclasses of TRPV1-positive neurons and a novel paracrine circuit. PLoS ONE, 2014-12-31;9(12):e115731. 2014-12-31 [PMID: 25551770] (IHC-Fr, Rat) IHC-Fr Rat

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Bioinformatics

Gene Symbol TRPV1
Uniprot