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Vang-like Protein 2/VANGL2 Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

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Vang-like Protein 2/VANGL2 Antibody Summary

Immunogen
Synthetic peptide derived from N-terminal domain of human VANGL2 protein
Specificity
Reacts with human 60 kDa VANGL2 protein.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VANGL2
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 1:10-1:2000
  • Western Blot 1:100-1:2000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Human, Mouse and Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
0.1M Tris , 0.1M Glycine and 2% Sucrose
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A purified
Reconstitution Instructions
Lyophilized powder, reconstituted in distilled water.

Alternate Names for Vang-like Protein 2/VANGL2 Antibody

  • KIAA1215Loop-tail protein 1 homolog
  • loop-tail-associated protein
  • LPP1
  • LTAP
  • LTAPVan Gogh-like protein 2
  • MGC119403
  • MGC119404
  • STB1
  • STB1Strabismus 1
  • STBM
  • STBM1
  • Strabismus
  • vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
  • Vang like Protein 2
  • VANGL2
  • vang-like 2 (van gogh, Drosophila)
  • Vang-like Protein 2

Background

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila strabismus/Van Gogh (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Vang-like Protein 2/VANGL2 Antibody (NBP2-21295) (0)

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol VANGL2
Entrez
Uniprot