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Dishevelled-1 Antibody

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Western Blot: Dishevelled-1 Antibody [NBP2-24648] - Analysis of Dishevelled-1 in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. Goat anti-rabbit Ig HRP secondary antibody and PicoTect ECL substrate solution were used for this test.
Western Blot: Dishevelled-1 Antibody [NBP2-24648] - Analysis of Dishevelled-1 in Raji cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody. Goat anti-rabbit Ig HRP secondary antibody ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Pm, Po, Ca, Ch, Pm, Pm, Ma-Op, RMSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

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Dishevelled-1 Antibody Summary

Immunogen
A portion of amino acids 70-120 of human DVL-1 was used as the immunogen.
Predicted Species
Porcine (100%), Chimpanzee (100%), Rhesus Macaque (100%), Opossum (100%), Monkey (100%), Chicken (100%), Canine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DVL1
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 5-7 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Protein A purified

Alternate Names for Dishevelled-1 Antibody

  • dishevelled 1 (homologous to Drosophila dsh)
  • dishevelled, dsh homolog 1 (Drosophila)
  • Dishevelled1
  • Dishevelled-1
  • DSH homolog 1
  • Dsh
  • DVL
  • DVL1
  • DVL1L1
  • MGC54245
  • segment polarity protein dishevelled homolog DVL-1

Background

DVL1, the human homolog of the Drosophila dishevelled gene (dsh) encodes a cytoplasmic phosphoprotein that regulates cell proliferation, acting as a transducer molecule for developmental processes, including segmentation and neuroblast specification. DVL1 is a candidate gene for neuroblastomatous transformation. The Schwartz-Jampel syndrome and Charcot-Marie-Tooth disease type 2A have been mapped to the same region as DVL1. The phenotypes of these diseases may be consistent with defects which might be expected from aberrant expression of a DVL gene during development. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DVL1
Uniprot