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Vang-like Protein 2/VANGL2 Antibody

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Immunohistochemistry-Paraffin: Vang-like Protein 2/VANGL2 Antibody [NBP1-81428] - Staining of human tonsil shows strong cytoplasmic positivity in reaction center cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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Vang-like Protein 2/VANGL2 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: QLQPQFTLKVVRSTDGASRFYNVGHLSIQRVAVWILEKYYHDFPVYNPALLNLPKSVLAKKVSGFKVYSLGEENSTNNSTGQSRAVIAAAARRRDNSHNEYYYEEAEHERRV
Predicted Species
Mouse (100%), Rat (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
VANGL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
Vang-like Protein 2/VANGL2 Protein (NBP1-81428PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Vang-like Protein 2/VANGL2 Antibody

  • KIAA1215Loop-tail protein 1 homolog
  • loop-tail-associated protein
  • LPP1
  • LTAP
  • LTAPVan Gogh-like protein 2
  • MGC119403
  • MGC119404
  • STB1
  • STB1Strabismus 1
  • STBM
  • STBM1
  • Strabismus
  • vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
  • Vang like Protein 2
  • VANGL2
  • vang-like 2 (van gogh, Drosophila)
  • Vang-like Protein 2

Background

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol VANGL2