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Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, ELISA
Clone
ARC5017-02
Clonality
Monoclonal
Host
Rabbit
Conjugate
Unconjugated

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Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02) Summary

Immunogen
A phospho specific peptide corresponding to residues surrounding S14/S17 of human Vang-like Protein 2/VANGL2

Sequence:
SGHSR
Modification
p Ser14, p Ser17
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
VANGL2
Purity
Affinity purified
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Applications/Dilutions

Dilutions
  • ELISA Recommended starting concentration is 1 ug/mL
  • Western Blot 1:500 - 1:1000
Theoretical MW
60 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.3), 50% glycerol, 0.05% BSA
Preservative
0.01% Thimerosal
Purity
Affinity purified

Alternate Names for Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)

  • KIAA1215Loop-tail protein 1 homolog
  • loop-tail-associated protein
  • LPP1
  • LTAP
  • LTAPVan Gogh-like protein 2
  • MGC119403
  • MGC119404
  • STB1
  • STB1Strabismus 1
  • STBM
  • STBM1
  • Strabismus
  • vang (van gogh, Drosophila)-like 2, vang, van gogh-like 2 (Drosophila)
  • Vang like Protein 2
  • VANGL2
  • vang-like 2 (van gogh, Drosophila)
  • Vang-like Protein 2

Background

VANGL2 is involved in the control of early morphogenesis and patterning of both axial midline structures and the development of neural plate. It plays a role in the regulation of planar cell polarity, particularly in the orientation of stereociliary bundles in the cochlea. It is required for polarization and movement of myocardializing cells in the outflow tract and seems to act via RHOA signaling to regulate this process. The VANGL2 gene encodes a homolog of Drosophila 'strabismus/Van Gogh' (Stbm/Vang), a component of the frizzled-dishevelled tissue polarity pathway.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Vang-like Protein
2/VANGL2 [p Ser17, p ...
NBP3-33566
Vang-like Protein 2/VANGL2 [p Ser17, p Ser14] Antibody (ARC5017-02)
Species: Rt
Applications: WB, ELISA

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Bioinformatics

Gene Symbol VANGL2