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TXNL1 Antibody

Images

 
Western Blot: TXNL1 Antibody [NBP1-86900] - Lane 1: NIH-3T3 cell lysate (Mouse embryonic fibroblast cells). Lane 2: NBT-II cell lysate (Rat Wistar bladder tumor cells).
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Staining of human Testis shows moderate cytoplasmic and nuclear positivity in cells in seminiferous ducts and Leydig cells.
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Staining of human cerebellum shows moderate nuclear positivity in Purkinje cells.
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Analysis in human thyroid gland and liver tissues using NBP1-86900 antibody. Corresponding TXNL1 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Staining of human Cerebral cortex shows moderate cytoplasmic and nuclear positivity in neuronal cells.
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Staining of human liver shows very weak cytoplasmic positivity in hepatocytes.
Immunohistochemistry-Paraffin: TXNL1 Antibody [NBP1-86900] - Staining of human Thyroid gland shows strong cytoplasmic and nuclear positivity in glandular cells.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TXNL1 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: LLLQFQSQWRRGHPAGLSVRMVGVKPVGSDPDFQPELSGAGSRLAVVKFTMRGCGPCLRIAPAFSSMSNKYPQAVFLEVDVHQCQGTAATNNISATPTFLFFRNKVRIDQYQGADAVGLEEKIKQHLENDPGSNEDTDIPKG
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TXNL1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 1:100-1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TXNL1 Protein (NBP1-86900PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TXNL1 Antibody

  • 32 kDa thioredoxin-related protein
  • thioredoxin-like 1
  • thioredoxin-like, 32kDa
  • thioredoxin-related 32 kDa protein
  • thioredoxin-related protein 1
  • TRP32thioredoxin-like protein 1
  • Txl
  • TXL-1
  • TXNL

Background

Thioredoxins are a group of small redox active proteins which have a conserved active site sequence. The predicted 32.3-kD protein of TXNL1 (Thioredoxin like protein 1) has 2 distinct domains: an N terminal domain, which is 43% identical to human TXN, and a C terminal domain, which showed no homology to other proteins in the sequence databases. The active site sequence, located within the N terminal domain, is that of a thioredoxin like protein; compared to the active site sequence of TXN, it has a single amino acid substitution. Unlike other thioredoxin like proteins, TXNL1 did not act as a substrate for thioredoxin reductase in an insulin assay.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TXNL1