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Troponin I Type 3 (cardiac) Antibody (4C2cc)

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Fe, Gt, RbSpecies Glossary
Applications WB, ELISA, IHC, IP, AP
Clone
4C2cc
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB110-8453AF350
Alexa Fluor 405
NB110-8453AF405
Alexa Fluor 488
NB110-8453AF488
Alexa Fluor 532
NB110-8453AF532
Alexa Fluor 594
NB110-8453AF594
Alexa Fluor 647
NB110-8453AF647
Alexa Fluor 700
NB110-8453AF700
Alexa Fluor 750
NB110-8453AF750
Biotin
NB110-8453B
DyLight 350
NB110-8453UV
DyLight 405
NB110-8453V
DyLight 488
NB110-8453G
DyLight 550
NB110-8453R
DyLight 594
NB110-8453DL594
DyLight 650
NB110-8453C
DyLight 680
NB110-8453FR
DyLight 755
NB110-8453IR
FITC
NB110-8453F
HRP
NB110-8453H
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Troponin I Type 3 (cardiac) Antibody (4C2cc) Summary

Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with free human cTnI.
Epitope
a.a.r. 23-29
Specificity
No cross-reaction with skeletal muscle TnI.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
TNNI3
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunoaffinity Purification
  • Immunoassay
  • Immunohistochemistry
  • Immunoprecipitation
  • Sandwich ELISA
  • Western Blot
Application Notes
Recommended pair for sandwich immunoassay (capture-detection): NB110-8453 - NB110-2546.
Theoretical MW
24 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Troponin I Type 3 (cardiac) Antibody (4C2cc)

  • Cardiac troponin I
  • CMD1FF
  • CMD2A
  • CMH7MGC116817
  • CTnI
  • familial hypertrophic cardiomyopathy 7
  • RCM1
  • TNNC1
  • TNNC1troponin I, cardiac
  • TNNI3,
  • troponin I type 3 (cardiac)
  • troponin I, cardiac muscle
  • Troponin I/TNNI3

Background

Troponin I is part of a heteromeric complex playing an important role in the regulation of skeletal and cardiac muscle contraction. It consists of three subunits, troponin I (TnI), troponin T (TnT) and troponin C (TnC). Each subunit is responsible for part of troponin complex function. TnI inhibits ATPase activity of acto myosin and TnT and TnI are present in cardiac muscles in different forms than in skeletal muscles. Only one tissue specific isoform of TnI is described for cardiac muscle tissue (cTnI) and this is expressed only in myocardium.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Troponin I Type 3
(cardiac) Antibody (4 ...
NB110-8453
Troponin I Type 3 (cardiac) Antibody (4C2cc)
Species: Hu, Mu, Rt, Po, Bv, Ca, Fe, Gt, Rb
Applications: WB, ELISA, IHC, IP, AP

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Blogs on Troponin I Type 3 (cardiac).

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Troponin I Type 3 (TnI, cardiac)
Troponin I is part of a heteromeric thin filament regulatory complex that governs skeletal and cardiac muscle contraction. Troponin I is composed of three subunits: troponin I (TnI), troponin T (TnT), and troponin C (TnC), and each of these components...  Read full blog post.
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Bioinformatics

Gene Symbol TNNI3
Entrez