TRAF-5 Antibody

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. NB100-56178 recognizes TRAF5. Mouse TRAF5 is a 558 amino acid protein.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 applications: IHC-P, WB.

Showing Publication 1 - 1 of 1.

Publication using NB100-56178	Applications	Species
Zapata JM, Krajewska M, Krajewski S et al. TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies. J Immunol. 2000-11-01 [PMID: 11046039] (WB, IHC-P) Details: WB: Figs 1, 2, 4, 5; IHC-paraffin: Fig 3.	WB, IHC-P

Array NB100-56178

• TRAF-5 Antibodies
• TRAF-5 ELISA Kits
• TRAF-5 Lysates
• TRAF-5 Proteins