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TOPORS Antibody

Images

 
Immunocytochemistry/ Immunofluorescence: TOPORS Antibody [NBP2-56069] - Staining of human cell line U-2 OS shows localization to nucleoplasm.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ICC/IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

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TOPORS Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: GGATCQIQGVQTNDDLNNDSDDSSDNCVIVGFVKPLAERTPELVELSSDSEDLGSYEKMETVKTQEQEQSYSSGDSDVSRCSSPHSVLGKDEQINKGHCDSSTRIKSKKEEKRSTSLSSPRNL
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TOPORS
Purity
Affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
TOPORS Recombinant Protein Antigen (NBP2-56069PEP)

Reactivity Notes

Mouse 85%, Rat 86%

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for TOPORS Antibody

  • EC 6.3.2.-
  • LUNtopoisomerase I binding, arginine/serine-rich
  • p53-binding protein 3
  • p53BP3
  • retinitis pigmentosa 31 (autosomal dominant)
  • RP31
  • SUMO1-protein E3 ligase Topors
  • topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • Topoisomerase I-binding arginine/serine-rich protein
  • Topoisomerase I-binding RING finger protein
  • TP53BPLE3 ubiquitin-protein ligase Topors
  • Tumor suppressor p53-binding protein 3

Background

TOPORS functions as an ubiquitin-protein E3 ligase and as an E3 SUMO1-protein ligase. Can both ubiquitinate and sumoylate p53

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TOPORS Antibody (NBP2-56069) (0)

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

FAQs for TOPORS Antibody (NBP2-56069) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TOPORS