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TOPORS Antibody

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Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human testis shows high expression.
Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining of human pancreas shows low expression as expected.
Orthogonal Strategies: Immunohistochemistry-Paraffin: TOPORS Antibody [NBP2-39060] - Staining in human testis and pancreas tissues using anti-TOPORS antibody. Corresponding TOPORS RNA-seq data are presented for ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
       

Orthogonal Strategies

 

Order Details

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TOPORS Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: IVQHIIMSNVTRYDLESQAFVSDLRPFLLNRTEHFIHEFISFARSPFNMAAFDQHANYDCPAPSYEEGSHSDSSVITISPDEAETQELDINVATVSQAPWDDETPGPSYSSSEQVHVTMSSLL
Predicted Species
Mouse (93%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TOPORS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
TOPORS Protein (NBP2-39060PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for TOPORS Antibody

  • EC 6.3.2.-
  • LUNtopoisomerase I binding, arginine/serine-rich
  • p53-binding protein 3
  • p53BP3
  • retinitis pigmentosa 31 (autosomal dominant)
  • RP31
  • SUMO1-protein E3 ligase Topors
  • topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
  • Topoisomerase I-binding arginine/serine-rich protein
  • Topoisomerase I-binding RING finger protein
  • TP53BPLE3 ubiquitin-protein ligase Topors
  • Tumor suppressor p53-binding protein 3

Background

TOPORS functions as an ubiquitin-protein E3 ligase and as an E3 SUMO1-protein ligase. Can both ubiquitinate and sumoylate p53

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TOPORS
Uniprot