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TIPRL Antibody

Images

 
Western Blot: TIPRL Antibody [NBP1-51995] - (1ug/ml) staining of K562 lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Immunohistochemistry-Paraffin: TIPRL Antibody [NBP1-51995] - 3.75ug/ml staining of paraffin embedded Human Breast. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

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TIPRL Antibody Summary

Immunogen
Peptide with sequence C-RIDPNPADSQKSTQ corresponding to C-Terminus according to NP_690866.1.
Epitope
C-RIDPNPADSQKSTQ
Specificity
This antibody is expected to recognize isoform 1 (NP_690866.1).
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
TIPRL
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1-3ug/ml
  • Immunohistochemistry-Paraffin
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1:1000
Application Notes
Western blot: Approx 30kDa band observed in lysates of cell line K562 (calculated MW of 31.4kDa according to NP_690866.1). Primary incubation was 1 hour
IHC: Paraffin embedded Human Breast.
Publications
Read Publication using NBP1-51995.

Reactivity Notes

Expected from sequence similarity: Mouse, Rat, Canine, Bovine

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TIPRL Antibody

  • dJ69E11.3
  • MGC3794
  • putative MAPK activating protein
  • Putative MAPK-activating protein PM10
  • TIP41, TOR signaling pathway regulator-like (S. cerevisiae)
  • TIP41-like protein
  • TIP41Type 2A-interacting protein
  • TIPTIP41, TOR signalling pathway regulator-like (S. cerevisiae)

Background

TIPRL is an inhibitory regulator of protein phosphatase-2A (PP2A) (see PPP2CA; MIM 176915), PP4 (see PPP4C; MIM 602035), and PP6 (see PPP6C; MIM 300141) (McConnell et al., 2007 [PubMed 17384681]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TIPRL Antibody (NBP1-51995)(1)

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Bioinformatics

Gene Symbol TIPRL
Entrez
Uniprot