Name: TIMP-1 Antibody (63515) [Unconjugated]
Brand: Novus Biologicals
SKU: MAB970
Price: 459 USD

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At	=	A. thaliana	SyHa	=	Golden Syrian Hamster
All	=	All Species	Ha	=	Hamster
An	=	Animal	Hu	=	Human
ArHa	=	Armenian Hamster	I	=	Insect
Av	=	Avian	Ll	=	Llama
Bb	=	Baboon	Ma	=	Mammal
Ba	=	Bacteria	Mk	=	Monkey
Bv	=	Bovine	Mu	=	Mouse
Ca	=	Canine	Multi	=	Multi-species
Ce	=	C. Elegans	NA	=	Non-species specific
Ch	=	Chicken	Or	=	Orangutan
ChHa	=	Chinese Hamster	Pl	=	Plant
Cm	=	Cynomolgus Monkey	Pm	=	Primate
Do	=	Donkey	Po	=	Porcine
Dr	=	Drosophilia	Rb	=	Rabbit
Ec	=	E. Coli	Rt	=	Rat
Eq	=	Equine	RM	=	Rhesus Macaque
Fe	=	Feline	Sh	=	Sheep
Ft	=	Ferret	Vb	=	Vertebrate
Fi	=	Fish	Vi	=	Virus
Fu	=	Fungi	Xp	=	Xenopus
Ge	=	Gerbil	Ye	=	Yeast
GP	=	Guinea Pig	Ze	=	Zebrafish
Gt	=	Goat

Reactivity	HuSpecies Glossary
Applications	WB, IHC, CyTOF-ready, ELISA(Cap), Flow, ICC/IF
Clone	63515
Clonality	Monoclonal
Host	Mouse
Conjugate	Unconjugated

Catalog# & Conjugate	Size	Price
Alexa Fluor 350 IC970U-100UG

Alexa Fluor 405 IC970V-100UG

Alexa Fluor 488 IC970G-100UG

Alexa Fluor 532 FAB970X

Alexa Fluor 594 IC970T-100UG

Alexa Fluor 647 IC970R-100UG

Alexa Fluor 700 IC970N-100UG

Alexa Fluor 750 IC970S-100UG

Allophycocyanin FAB970A

Biotin FAB970B

CoraFluor 1 FAB970CL1

DyLight 350 FAB970D

DyLight 405 FAB970E

DyLight 488 FAB970K

DyLight 550 FAB970L

DyLight 594 FAB970M

DyLight 650 FAB970W

DyLight 680 FAB970Y

DyLight 755 FAB970Z

FITC FAB970F

HRP FAB970H

Janelia Fluor 525 FAB970JF525

Janelia Fluor 549 FAB970I

Janelia Fluor 585 FAB970JF585

Janelia Fluor 635 FAB970JF635

Janelia Fluor 646 FAB970J

Janelia Fluor 669 FAB970JF669

PE FAB970P

PerCP FAB970C

mFluor Violet 450 SE FAB970MFV450

mFluor Violet 500 SE FAB970MFV500

mFluor Violet 610 SE FAB970MFV610

Catalog# & Formulation	Size	Price
Carrier Free MAB970-SP

Carrier Free MAB970-500

Carrier Free IC970U-100UG

Carrier Free IC970T-100UG

Carrier Free IC970S-100UG

Carrier Free IC970R-100UG

Carrier Free IC970V-100UG

Carrier Free IC970N-100UG

Carrier Free IC970G-100UG

Conjugate	Catalog #	Availability	Size	Price
Alexa Fluor 350	IC970U-100UG
Alexa Fluor 405	IC970V-100UG
Alexa Fluor 488	IC970G-100UG
Alexa Fluor 532	FAB970X
Alexa Fluor 594	IC970T-100UG
Alexa Fluor 647	IC970R-100UG
Alexa Fluor 700	IC970N-100UG
Alexa Fluor 750	IC970S-100UG
Allophycocyanin	FAB970A
Biotin	FAB970B
CoraFluor 1	FAB970CL1
DyLight 350	FAB970D
DyLight 405	FAB970E
DyLight 488	FAB970K
DyLight 550	FAB970L
DyLight 594	FAB970M
DyLight 650	FAB970W
DyLight 680	FAB970Y
DyLight 755	FAB970Z
FITC	FAB970F
HRP	FAB970H
Janelia Fluor 525	FAB970JF525
Janelia Fluor 549	FAB970I
Janelia Fluor 585	FAB970JF585
Janelia Fluor 635	FAB970JF635
Janelia Fluor 646	FAB970J
Janelia Fluor 669	FAB970JF669
PE	FAB970P
PerCP	FAB970C
mFluor Violet 450 SE	FAB970MFV450
mFluor Violet 500 SE	FAB970MFV500
mFluor Violet 610 SE	FAB970MFV610

TIMP-1 Antibody (63515) [Unconjugated]

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TIMP-1 Antibody (63515) [Unconjugated] Summary

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Alternate Names for TIMP-1 Antibody (63515) [Unconjugated]

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Publications for TIMP-1 Antibody (MAB970)(19)

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Immunogen	Mouse myeloma cell line NS0-derived recombinant human TIMP-1 Cys24-Ala207 Accession # P01033
Specificity	Detects human TIMP-1 in ELISAs and Western blots. In ELISAs, this antibody does not cross-react with recombinant mouse TIMP‑1 or recombinant human TIMP‑2.
Source	N/A
Isotype	IgG2b
Clonality	Monoclonal
Host	Mouse
Gene	TIMP1
Purity Statement	Protein A or G purified from hybridoma culture supernatant
Innovator's Reward	Test in a species/application not listed above to receive a full credit towards a future purchase. Learn about the Innovator's Reward

Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer	Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative	No Preservative
Reconstitution Instructions	Reconstitute at 0.5 mg/mL in sterile PBS.

Publications using MAB970	Applications	Species
SB Wu, TY Hou, HC Kau, CC Tsai Effect of Pirfenidone on TGF-beta1-Induced Myofibroblast Differentiation and Extracellular Matrix Homeostasis of Human Orbital Fibroblasts in Graves' Ophthalmopathy Biomolecules, 2021-09-29;11(10):. 2021-09-29 [PMID: 34680057] (Western Blot, Human)	Western Blot	Human
TY Hou, SB Wu, HC Kau, CC Tsai JNK and p38 Inhibitors Prevent Transforming Growth Factor-&beta1-Induced Myofibroblast Transdifferentiation in Human Graves' Orbital Fibroblasts International Journal of Molecular Sciences, 2021-03-14;22(6):. 2021-03-14 [PMID: 33799469] (Western Blot, Human)	Western Blot	Human
W Xiao, L Wang, J Howard, R Kolhe, AM Rojiani, MV Rojiani TIMP-1-Mediated Chemoresistance via Induction of IL-6 in NSCLC Cancers (Basel), 2019-08-15;11(8):. 2019-08-15 [PMID: 31443242] (ELISA Capture, Human)	ELISA Capture	Human
Timo Carpén, Timo Sorsa, Lauri Jouhi, Taina Tervahartiala, Caj Haglund, Stina Syrjänen et al. High levels of tissue inhibitor of metalloproteinase-1 (TIMP-1) in the serum are associated with poor prognosis in HPV-negative squamous cell oropharyngeal cancer Cancer Immunology, Immunotherapy 8/1/2019 [PMID: 31240326]
X Wang, J Rojas-Quin, J Wilder, Y Tesfaigzi, D Zhang, CA Owen Tissue Inhibitor of Metalloproteinase-1 Promotes Polymorphonuclear Neutrophil (PMN) Pericellular Proteolysis by Anchoring Matrix Metalloproteinase-8 and -9 to PMN Surfaces J. Immunol., 2019-04-24;0(0):. 2019-04-24 [PMID: 31019060] (ICC, Primate)	ICC	Primate
Qing Kay Li, Li Chen, Ming-Hui Ao, Joyce Hanching Chiu, Zhen Zhang, Hui Zhang et al. Serum Fucosylated Prostate-specific Antigen (PSA) Improves the Differentiation of Aggressive from Non-aggressive Prostate Cancers Theranostics 1/1/2015 [PMID: 25553114]
Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF, Walsh SW Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction. Am. J. Pathol., 2010-12-23;178(1):451-60. 2010-12-23 [PMID: 21224082] (Western Blot, Human)	Western Blot	Human
Schipper HS, De Jager W, van Dijk ME, Meerding J, Zelissen PM, Adan RA, Prakken BJ, Kalkhoven E A multiplex immunoassay for human adipokine profiling. Clin. Chem., 2010-06-08;56(0):1320. 2010-06-08 [PMID: 20530731] (Luminex Development, Human)	Luminex Development	Human
Li MQ, Hou XF, Shao J, Tang CL, Li DJ The DSCs-expressed CD82 controls the invasiveness of trophoblast cells via integrinbeta1/MAPK/MAPK3/1 signaling pathway in human first-trimester pregnancy. Biol. Reprod., 2010-01-14;82(5):968-79. 2010-01-14 [PMID: 20075392] (Cell-based ELISA, Human)	Cell-based ELISA	Human
Lucio-Eterovic AK, Piao Y, de Groot JF Mediators of glioblastoma resistance and invasion during antivascular endothelial growth factor therapy. Clin. Cancer Res., 2009-06-30;15(14):4589-99. 2009-06-30 [PMID: 19567589] (ICC, Western Blot, Human)	ICC, Western Blot	Human
Cavallo C, Desando G, Facchini A, Grigolo B Chondrocytes from patients with osteoarthritis express typical extracellular matrix molecules once grown onto a three-dimensional hyaluronan-based scaffold. J Biomed Mater Res A, 2010-04-01;93(1):86-95. 2010-04-01 [PMID: 19484766] (ICC, Human)	ICC	Human
Villeneuve J, Block A, Le Bousse-Kerdiles MC, Lepreux S, Nurden P, Ripoche J, Nurden AT Tissue inhibitors of matrix metalloproteinases in platelets and megakaryocytes: a novel organization for these secreted proteins. Exp. Hematol., 2009-05-03;37(7):849-56. 2009-05-03 [PMID: 19410025] (ICC, Human)	ICC	Human
Kong MY, Gaggar A, Li Y Matrix metalloproteinase activity in pediatric acute lung injury. Int J Med Sci, 2008-12-16;6(1):9-17. 2008-12-16 [PMID: 19159011] (Western Blot, Human)	Western Blot	Human
Nicol GR, Han M, Kim J, Birse CE, Brand E, Nguyen A, Mesri M, FitzHugh W, Kaminker P, Moore PA, Ruben SM, He T Use of an immunoaffinity-mass spectrometry-based approach for the quantification of protein biomarkers from serum samples of lung cancer patients. Mol. Cell Proteomics, 2008-04-03;7(10):1974-82. 2008-04-03 [PMID: 18388126] (Mass Spectrometry, Human)	Mass Spectrometry	Human
Naveau A, Reinald N, Fournier B Gingival fibroblasts inhibit MMP-1 and MMP-3 activities in an ex-vivo artery model. Connect. Tissue Res., 2007-01-01;48(6):300-8. 2007-01-01 [PMID: 18075816] (Dot Blot, Human)	Dot Blot	Human
Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis. J. Immunol., 2007-05-01;178(9):5957-65. 2007-05-01 [PMID: 17442980] (Western Blot, Human)	Western Blot	Human
Monteleone G, Caruso R, Fina D, Peluso I, Gioia V, Stolfi C, Fantini MC, Caprioli F, Tersigni R, Alessandroni L, MacDonald TT, Pallone F Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21. Gut, 2006-05-08;55(12):1774-80. 2006-05-08 [PMID: 16682426] (Western Blot, Human)	Western Blot	Human
Djafarzadeh R, Noessner E, Engelmann H GPI-anchored TIMP-1 treatment renders renal cell carcinoma sensitive to FAS-meditated killing. Oncogene, 2006;25(10):1496-508. 2006 [PMID: 16261161] (ELISA Development, Human)	ELISA Development	Human
Wilson MJ, Jiang A, Wiehr C, Wang X, Sinha AA, Pei D Limited processing of pro-matrix metalloprotease-2 (gelatinase A) overexpressed by transfection in PC-3 human prostate tumor cells: association with restricted cell surface localization of membrane-type matrix metalloproteinase-1. J. Androl., 2004-03-01;25(2):274-85. 2004-03-01 [PMID: 14760014] (Western Blot, Human)	Western Blot	Human
Show All 19 Publications. Collapse Publications.

Gene Symbol	TIMP1
Uniprot	P01033()