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Thimet Oligopeptidase/THOP1 Antibody (4D6) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Pm, RbSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
4D6
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

Thimet Oligopeptidase/THOP1 Antibody (4D6) [Biotin] Summary

Immunogen
A synthetic peptide corresponding to residues 56-72 of human Thimet Oligopeptidase. [UniProt# P52888]
Localization
Cytoplasmic
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Gene
THOP1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Alternate Names for Thimet Oligopeptidase/THOP1 Antibody (4D6) [Biotin]

  • EC 3.4.24
  • EC 3.4.24.15
  • Endopeptidase 24.15
  • EP24.15
  • MEPD_HUMAN
  • MP78
  • thimet oligopeptidase 1
  • thimet oligopeptidase
  • THOP1
  • TOP

Background

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enxymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Thimet Oligopeptidase/THOP1 Antibody (NB400-146B) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol THOP1