Home » TGF-beta RI/ALK-5 » TGF-beta RI/ALK-5 Antibodies » TGF-beta RI/ALK-5 Antibody (RM0016-3A11) [Janelia Fluor® 549]
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TGF-beta RI/ALK-5 Antibody (RM0016-3A11) [Janelia Fluor® 549]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, IHC
Clone
RM0016-3A11
Clonality
Monoclonal
Host
Rat
Conjugate
Janelia Fluor 549

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-11921AF350
Alexa Fluor 405
NBP2-11921AF405
Alexa Fluor 488
NBP2-11921AF488
Alexa Fluor 532
NBP2-11921AF532
Alexa Fluor 594
NBP2-11921AF594
Alexa Fluor 647
NBP2-11921AF647
Alexa Fluor 700
NBP2-11921AF700
Alexa Fluor 750
NBP2-11921AF750
Allophycocyanin
NBP2-11921APC
Biotin
NBP2-11921B
DyLight 350
NBP2-11921UV
DyLight 405
NBP2-11921V
DyLight 488
NBP2-11921G
DyLight 550
NBP2-11921R
DyLight 594
NBP2-11921DL594
DyLight 650
NBP2-11921C
DyLight 680
NBP2-11921FR
DyLight 755
NBP2-11921IR
FITC
NBP2-11921F
HRP
NBP2-11921H
Janelia Fluor 646
NBP2-11921JF646
PE
NBP2-11921PE
PerCP
NBP2-11921PCP
Unconjugated
NBP2-11921
mFluor Violet 450 SE
NBP2-11921MFV450
mFluor Violet 500 SE
NBP2-11921MFV500
mFluor Violet 610 SE
NBP2-11921MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-11921
Azide and BSA Free
NBP2-11921
Azide and BSA Free
NBP2-11921-0.025mg
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TGF-beta RI/ALK-5 Antibody (RM0016-3A11) [Janelia Fluor® 549] Summary

Immunogen
Mouse TGF-beta RI/ALK-5 (extracellular domain)
Isotype
IgG2
Clonality
Monoclonal
Host
Rat
Gene
TGFBR1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TGF-beta RI/ALK-5 Antibody (RM0016-3A11) [Janelia Fluor® 549]

  • AAT5
  • activin A receptor type II-like kinase, 53kD
  • activin A receptor type II-like kinase, 53kDa
  • Activin receptor-like kinase 5
  • ACVRLK4
  • ALK-5
  • ALK-5ALK5
  • EC 2.7.11
  • EC 2.7.11.30
  • LDS1A
  • LDS2A
  • Serine/threonine-protein kinase receptor R4
  • SKR4
  • tbetaR-I
  • TGFB1R1
  • TGF-beta receptor type I
  • TGF-beta receptor type-1
  • TGF-beta RI
  • TGF-beta type I receptor
  • TGFbetaRI
  • TGFBR1
  • TGF-bRI
  • TGFR-1
  • transforming growth factor beta receptor I
  • transforming growth factor, beta receptor 1
  • transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD)
  • Transforming growth factor-beta receptor type I

Background

TGF beta Receptor I is encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol TGFBR1