![SDS-Page: Recombinant Human TDP-43/TARDBP Protein [NBP2-59551] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.](http://images.novusbio.com/fullsize/Recombinant Human TDP-43-TARDBP Protein-SDS-Page-NBP2-59551-img0003.jpg "SDS-Page: Recombinant Human TDP-43/TARDBP Protein [NBP2-59551] - 3ug by SDS-PAGE under reducing condition and visualized by coomassie blue stain.")
| Reactivity | HuSpecies Glossary |
| Applications | PAGE |
| Concentration | 0.25 mg/ml |
| Description | An un-tagged recombinant protein corresponding to the amino acids 1-414 of Human TDP-43/TARDBP Source: E.coli Amino Acid Sequence: MSEYIRVTED ENDEPIEIPS EDDGTVLLST VTAQFPGACG LRYRNPVSQC MRGVRLVEGI LHAPDAGWGN LVYVVNYPKD NKRKMDETDA SSAVKVKRAV QKTSDLIVLG LPWKTTEQDL KEYFSTFGEV LMVQVKKDLK TGHSKGFGFV RFTEYETQVK VMSQRHMIDG RWCDCKLPNS KQSQDEPLRS RKVFVGRCTE DMTEDELREF FSQYGDVMDV FIPKPFRAFA FVTFADDQIA QSLCGEDLII KGISVHISNA EPKHNSNRQL ERSGRFGGNP GGFGNQGGFG NSRGGGAGLG NNQGSNMGGG MNFGAFSINP AMMAAAQAAL QSSWGMMGML ASQQNQSGPS GNNQNQGNMQ REPNQAFGSG NNSYSGSNSG AAIGWGSASN AGSGSGFNGG FGSSMDSKSS GWGM |
| Source | E. coli |
| Protein/Peptide Type | Recombinant Protein |
| Gene | TARDBP |
| Purity | >85%, by SDS-PAGE |
| Dilutions |
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| Theoretical MW | 44.7 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
| Storage | Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer | 20 mM Tris-HCl buffer (pH8.0), 0.1 M NaCl, 1 mM DTT, 1 mM EDTA, 10% glycerol |
| Preservative | No Preservative |
| Concentration | 0.25 mg/ml |
| Purity | >85%, by SDS-PAGE |
Research Areas for TDP-43/TARDBP Recombinant Protein (NBP2-59551)Find related products by research area.
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| Gene Symbol | TARDBP |
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![Western Blot: TDP-43/TARDBP Antibody (2E2-D3) [H00023435-M01] - PDI co-precipitates with TDP-43/TARDBP and is increased in mutant TDP-43 transgenic mouse spinal cords. Co-immunoprecipitation of wildtype and mutant Q331K TDP-43-mCherry from Neuro2a cell lysates using an anti-PDI antibody followed by TDP-43 immunoblot. Control immunoprecipitations were performed using untransfected (Untrans) or mCherry expressing cell lysates, buffer only with coprecipitating antibodies or TDP-43 Q331K cell lysates using an irrelevant, isotype-matched control antibody (IgG). Input control (2%) shows expression of mCherry-TDP43 in wildtype and Q331K cell lysates. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0081170) licensed under a CC-BY license.](https://images.novusbio.com/images/TDP-43-TARDBP-Antibody-2E2-D3-Western-Blot-H00023435-M01-img0028.jpg "Western Blot: TDP-43/TARDBP Antibody (2E2-D3) [H00023435-M01] - PDI co-precipitates with TDP-43/TARDBP and is increased in mutant TDP-43 transgenic mouse spinal cords. Co-immunoprecipitation of wildtype and mutant Q331K TDP-43-mCherry from Neuro2a cell lysates using an anti-PDI antibody followed by TDP-43 immunoblot. Control immunoprecipitations were performed using untransfected (Untrans) or mCherry expressing cell lysates, buffer only with coprecipitating antibodies or TDP-43 Q331K cell lysates using an irrelevant, isotype-matched control antibody (IgG). Input control (2%) shows expression of mCherry-TDP43 in wildtype and Q331K cell lysates. Image collected and cropped by CiteAb from the following publication (https://dx.plos.org/10.1371/journal.pone.0081170) licensed under a CC-BY license.")