TDP-43/TARDBP Antibody Blocking Peptide Summary
Description |
A TARDBP antibody blocking peptide. |
Specificity |
This peptide is specific for NB110-55376 only. |
Protein/Peptide Type |
Antibody Blocking Peptide |
Gene |
TARDBP |
Applications/Dilutions
Dilutions |
|
Application Notes |
This peptide is useful as a blocking peptide for NB110-55376. For further blocking peptide related protocol, click here. |
Packaging, Storage & Formulations
Storage |
Store at -80C. Avoid freeze-thaw cycles. |
Buffer |
Peptide dissolved in dH2O. Contains no BSA. |
Preservative |
No Preservative |
Concentration |
1.0 mg/ml |
Alternate Names for TDP-43/TARDBP Antibody Blocking Peptide
Background
TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 3 months from date of receipt.
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