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Human TDP-43/TARDBP ELISA Kit (Chemiluminescence)

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ELISA: Human TDP-43/TARDBP ELISA Kit (Chemiluminescence) [NBP2-62770] - Samples were spiked with high concentrations of Human TDP-43/TARDBP and diluted with Reference Standard & Sample Diluent to produce samples with ...read more
ELISA: Human TDP-43/TARDBP ELISA Kit (Chemiluminescence) [NBP2-62770] - Standard Curve Reference

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Suitable Sample Type
Serum, plasma and other biological fluids
Standard Curve Range
62.50-4000 pg/mL
Sensitivity
37.50 pg/mL

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Human TDP-43/TARDBP ELISA Kit (Chemiluminescence) Summary

Specificity
This kit recognizes Human TDP43 in samples. No significant cross-reactivity or interference between Human TDP43 and analogues was observed.
Standard Curve Range
62.50-4000 pg/mL
Sensitivity
37.50 pg/mL
Assay Type
Sandwich-CLIA
Inter-Assay
CV% < 9.10%
Intra-Assay
CV% < 9.10%
Spike Recovery
89-112%
Sample Volume
100 uL
Kit Type
ELISA Kit (Chemiluminescence)
Gene
TARDBP

Applications/Dilutions

Dilutions
  • ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Biotinylated Detection Ab Diluent
  2. Concentrated Biotinylated Detection Ab (100x)
  3. Concentrated HRP Conjugate (100x)
  4. Concentrated Wash Buffer (25x)
  5. HRP Conjugate Diluent
  6. Micro CLIA Plate
  7. Plate Sealer
  8. Product Manual
  9. Reference Standard
  10. Sample Diluent
  11. Substrate Reagent A
  12. Substrate Reagent B

Alternate Names for Human TDP-43/TARDBP ELISA Kit (Chemiluminescence)

  • ALS10
  • ALS10TAR DNA-binding protein-43
  • TAR DNA binding protein
  • TARDBP
  • TDP43
  • TDP-43
  • TDP-43TAR DNA-binding protein 43

Background

TARDBP, also known as TAR DNA binding protein, is a DNA and RNA-binding protein which regulates transcription and splicing. TARDBP is also involved in the regulation of CFTR splicing and promotes CFTR exon 9 skipping by binding to the UG repeated motifs in the polymorphic region near the 3'-splice site of this exon. The resulting aberrant splicing is associated with pathological features typical of cystic fibrosis. TARD-BP may also be involved in microRNA biogenesis, apoptosis and cell division. TARDBP can repress HIV-1 transcription by binding to the HIV-1 long terminal repeat.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol TARDBP