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STI1 Antibody

Images

 
Independent Antibodies: Western Blot: STI1 Antibody [NBP2-33411] - Analysis using Anti-STIP1 antibody NBP2-33411 (A) shows similar pattern to independent antibody NBP2-32621 (B).
Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human cerebral cortex.
Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human testis shows strong cytoplasmic positivity in basal cells of the seminiferous ducts.
Independent Antibodies: Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human cerebral cortex, colon, pancreas and testis using Anti-STIP1 antibody NBP2-33411 (A) shows similar protein ...read more
Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human pancreas.
Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human colon.
Immunohistochemistry-Paraffin: STI1 Antibody [NBP2-33411] - Staining of human testis.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Validated by:
 

Independent Antibodies

       

Order Details

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STI1 Antibody Summary

Immunogen
This antibody was developed against a recombinant protein corresponding to amino acids: YARIGNSYFKEEKYKDAIHFYNKSLAEHRTPDVLKKCQQAEKILKEQERLAYINPDLALEEKNKGNECFQKGDYPQAMKHYTEAIKRNPKDAKLYS
Predicted Species
Mouse (99%), Rat (98%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STIP1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Control Peptide
STI1 Protein (NBP2-33411PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for STI1 Antibody

  • HOP
  • HOPSTI1L
  • Hsc70/Hsp90-organizing protein
  • Hsp70/Hsp90-organizing protein
  • IEF-SSP-3521
  • NY-REN-11 antigen
  • NY-REN-11
  • Renal carcinoma antigen NY-REN-11
  • STI1
  • STI1L
  • STI1P60
  • STIP1
  • stress-induced-phosphoprotein 1
  • Transformation-sensitive protein IEF SSP 3521

Background

STIP1 is an adaptor protein that coordinates the functions of HSP70 (see HSPA1A; MIM 140550) and HSP90 (see HSP90AA1; MIM 140571) in protein folding. It is thought to assist in the transfer of proteins from HSP70 to HSP90 by binding both HSP90 and substrate-bound HSP70. STIP1 also stimulates the ATPase activity of HSP70 and inhibits the ATPase activity of HSP90, suggesting that it regulates both the conformations and ATPase cycles of these chaperones (Song and Masison, 2005 (PubMed 16100115)).(supplied by OMIM)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for STI1 Antibody (NBP2-33411) (0)

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Secondary Antibodies

 

Isotype Controls

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Research Areas for STI1 Antibody (NBP2-33411)

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Blogs on STI1.

Chaperone Mediated Autophagy (CMA) does it all!
By Christina Towers, PhD. The degradation of cellular proteins is a critical step of both regulation and quality control and results in the turn over and recycling of critical amino acids. The two main mechanisms o...  Read full blog post.

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Bioinformatics

Gene Symbol STIP1
Uniprot