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STAT6 [p Tyr641] Antibody (1248D) [Phycoerythrin]

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Human peripheral blood mononuclear cells (PBMCs) either (A) Th2-stimulated or (B) unstimulated were stained with Rabbit Anti-Human Phospho-STAT6 (Y641) PE-conjugated Monoclonal Antibody (Catalog # IC37173P) and Mouse Anti-Human CD4 APC-conjugated Monoclonal Antibody (Catalog # FAB3791A). Quadrant markers were set based on control antibody staining (Catalog # IC1051P). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with methanol. View our protocol for Staining Intracellular Molecules.
Human peripheral blood mononuclear cells (PBMCs) either (A) Th2-stimulated or (B) unstimulated were stained with Rabbit Anti-Human Phospho-STAT6 (Y641) PE-conjugated Monoclonal Antibody (Catalog # IC37173P) and Mouse ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Flow
Clone
1248D
Clonality
Monoclonal
Host
Rabbit
Conjugate
Phycoerythrin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC3717U-100UG
Alexa Fluor 405
IC3717V-100UG
Alexa Fluor 488
IC3717G-100UG
Alexa Fluor 532
FAB3717X
Alexa Fluor 594
IC3717T-100UG
Alexa Fluor 647
FAB3717R
Alexa Fluor 700
IC3717N-100UG
Alexa Fluor 750
IC3717S-100UG
Allophycocyanin
FAB3717A
Biotin
FAB3717B
CoraFluor 1
FAB3717CL1
DyLight 350
FAB3717D
DyLight 405
FAB3717E
DyLight 488
FAB3717K
DyLight 550
FAB3717L
DyLight 594
FAB3717M
DyLight 650
FAB3717W
DyLight 680
FAB3717Y
DyLight 755
FAB3717Z
FITC
FAB3717F
HRP
FAB3717H
Janelia Fluor 525
FAB3717JF525
Janelia Fluor 549
FAB3717I
Janelia Fluor 646
FAB3717J
Janelia Fluor 669
FAB3717JF669
PerCP
FAB3717C
Unconjugated
MAB3717
mFluor Violet 450 SE
FAB3717MFV450
mFluor Violet 500 SE
FAB3717MFV500
mFluor Violet 610 SE
FAB3717MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB3717
Carrier Free
MAB3717
Carrier Free
MAB3717-SP
Carrier Free
IC3717V-100UG
Carrier Free
IC3717U-100UG
Carrier Free
IC3717T-100UG
Carrier Free
IC3717S-100UG
Carrier Free
IC3717G-100UG
Carrier Free
IC3717N-100UG
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STAT6 [p Tyr641] Antibody (1248D) [Phycoerythrin] Summary

Additional Information
Recombinant Monoclonal Antibody.
Immunogen
Phosphopeptide containing human STAT6 Y641 site.
Accession # P42226
Modification
p Tyr641
Specificity
Detects human STAT6 when phosphorylated at Y641.
Source
N/A
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Purity Statement
Protein A or G purified from cell culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for STAT6 [p Tyr641] Antibody (1248D) [Phycoerythrin]

  • D12S1644
  • EC 2.4.1.227
  • EC 2.7.7.6
  • IL-4 Stat
  • IL-4-STAT
  • signal transducer and activator of transcription 6
  • signal transducer and activator of transcription 6, interleukin-4 induced
  • STAT, interleukin-4 induced
  • STAT, interleukin4-induced
  • STAT6
  • STAT6B
  • STAT6C
  • transcription factor IL-4 STAT

Background

Signal Transducer and Activator of Transcription 6 (STAT6) mediates the signaling of cytokines such as IL-4 and IL-13. STAT6 acts as a signal transducer in the cytoplasm and, upon phosphorylation at Y641, translocates to the nucleus and binds to the DNA consensus site TTCN4GAA. Knockout studies in mice suggest that STAT6 functions in differentiation of T helper 2 (Th2) cells, expression of cell surface markers, and class switch of immunoglobulins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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