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SSX2 Antibody (OTI4D10) [Janelia Fluor® 646]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF, IHC
Clone
OTI4D10
Clonality
Monoclonal
Host
Mouse
Conjugate
Janelia Fluor 646

Order Details

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SSX2 Antibody (OTI4D10) [Janelia Fluor® 646] Summary

Immunogen
Full-length protein expressed in 293T cell transfected with human SSX2 expression vector.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
SSX2
Purity
Immunogen affinity purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SSX2 Antibody (OTI4D10) [Janelia Fluor® 646]

  • Cancer/testis antigen 5.2
  • cancer/testis antigen family 5, member 2a
  • CT5.2a
  • HD21
  • HOM-MEL-40
  • MGC119055
  • MGC15364
  • MGC3884
  • protein SSX2
  • sarcoma, synovial, X-chromosome-related 2
  • SSX
  • SSX2A
  • SSX2B
  • synovial sarcoma, X breakpoint 2B
  • synovial sarcoma, X breakpoint 2CT5.2
  • Tumor antigen HOM-MEL-40

Background

The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SSX2 Antibody (NBP2-74368JF646) (0)

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SSX2