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SOX2 Antibody (245610) [Allophycocyanin]

 (5 Publications)
 (1 Review)
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NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/Mouse SOX2 APC-conjugated Monoclonal Antibody (Catalog # IC2018A, filled histogram) or isotype control antibody (Catalog # IC003A, open histogram). To facilitate intracellular staining, cells were fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005). View our protocol for Staining Intracellular Molecules.
NTera-2 human testicular embryonic carcinoma cell line was stained with Mouse Anti-Human/Mouse SOX2 APC-conjugated Monoclonal Antibody (Catalog # IC2018A, filled histogram) or isotype control antibody (Catalog # IC003A, ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications Flow
Clone
245610
Clonality
Monoclonal
Host
Mouse
Conjugate
Allophycocyanin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
IC2018U-100UG
Alexa Fluor 405
IC2018V-100UG
Alexa Fluor 488
IC2018G
Alexa Fluor 532
FAB2018X
Alexa Fluor 594
IC2018T-100UG
Alexa Fluor 647
IC2018R-100UG
Alexa Fluor 700
IC2018N-100UG
Alexa Fluor 750
IC2018S-100UG
Biotin
FAB2018B
CoraFluor 1
FAB2018CL1
DyLight 350
FAB2018D
DyLight 405
FAB2018E
DyLight 488
FAB2018K
DyLight 550
FAB2018L
DyLight 594
FAB2018M
DyLight 650
FAB2018W
DyLight 680
FAB2018Y
DyLight 755
FAB2018Z
FITC
FAB2018F
HRP
FAB2018H
Janelia Fluor 525
FAB2018JF525
Janelia Fluor 549
FAB2018I
Janelia Fluor 646
FAB2018J
Janelia Fluor 669
FAB2018JF669
Phycoerythrin
IC2018P-025
Phycoerythrin
IC2018P-100
Unconjugated
MAB2018
mFluor Violet 450 SE
FAB2018MFV450
mFluor Violet 500 SE
FAB2018MFV500
mFluor Violet 610 SE
FAB2018MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
MAB2018
Carrier Free
MAB2018
Carrier Free
IC2018G
Carrier Free
MAB2018-SP
Carrier Free
IC2018P-100
Carrier Free
IC2018P-025
Carrier Free
IC2018V-100UG
Carrier Free
IC2018U-100UG
Carrier Free
IC2018T-100UG
Carrier Free
IC2018S-100UG
Carrier Free
IC2018R-100UG
Carrier Free
IC2018N-100UG
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SOX2 Antibody (245610) [Allophycocyanin] Summary

Immunogen
E. coli-derived recombinant human SOX2
Gly135-Met317
Accession # P48431
Specificity
Detects human and mouse SOX2 in Western blots.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
SOX2
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
Learn about the Innovator's Reward

Applications/Dilutions

Dilutions
  • Intracellular Staining by Flow Cytometry 10 uL/10^6 cells
Reviewed Applications
Read 1 Review rated 4
using
IC2018A in the following application:
Publications
Read Publications using
IC2018A in the following applications:

Packaging, Storage & Formulations

Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.
Buffer
Supplied in a saline solution containing BSA and Sodium Azide.
Preservative
Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SOX2 Antibody (245610) [Allophycocyanin]

  • ANOP3
  • MCOPS3
  • MGC2413
  • SOX2
  • SRY (sex determining region Y)-box 2
  • SRY-related HMG-box gene 2
  • transcription factor SOX2
  • transcription factor SOX-2

Background

SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-5).
  1. Graham, V. et al. (2003) Neuron 39:749.
  2. Avilion, A.A. et al. (2003) Genes Dev. 17:126.
  3. Kishi, M. et al. (2000) Development 127:791.
  4. Yuan, H. et al. (1995) Genes Dev. 9:2635.
  5. Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
  6. Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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SOX2 Antibody
(245610) [Allophycocy ...
IC2018A
SOX2 Antibody (245610) [Allophycocyanin]
Species: Hu, Mu
Applications: Flow

Publications for SOX2 Antibody (IC2018A)(5)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: Flow Cytometry.


Filter By Application
Flow Cytometry
(4)
All Applications
Filter By Species
Human
(3)
Mouse
(1)
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Showing Publications 1 - 5 of 5.
Publications using IC2018A Applications Species
Mousavi Mirkalaei, S;Farivar, S; Systematic optimization of culture media for maintenance of human induced pluripotent stem cells using the response surface methodology Heliyon 2024-06-30 [PMID: 38975108] (Flow Cytometry, Human) Flow Cytometry Human
Lemarié, A;Lubrano, V;Delmas, C;Lusque, A;Cerapio, JP;Perrier, M;Siegfried, A;Arnauduc, F;Nicaise, Y;Dahan, P;Filleron, T;Mounier, M;Toulas, C;Cohen-Jonathan Moyal, E; The STEMRI trial: Magnetic resonance spectroscopy imaging can define tumor areas enriched in glioblastoma stem-like cells Science advances 2023-11-03 [PMID: 37922359] (Flow Cytometry, Human) Flow Cytometry Human
Vincent Le Coz, Chaobin Zhu, Aurore Devocelle, Aimé Vazquez, Claude Boucheix, Sandy Azzi et al. IGF-1 contributes to the expansion of melanoma-initiating cells through an epithelial-mesenchymal transition process Oncotarget 12/13/2016 [PMID: 27764776]
Huijbers I, Bin Ali R, Pritchard C, Cozijnsen M, Kwon M, Proost N, Song J, de Vries H, Badhai J, Sutherland K, Krimpenfort P, Michalak E, Jonkers J, Berns A Rapid target gene validation in complex cancer mouse models using re-derived embryonic stem cells. EMBO Mol Med, 2014-01-08;6(2):212-25. 2014-01-08 [PMID: 24401838] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Liu C, Luo D, Reynolds BA Chemokine receptor CXCR3 promotes growth of glioma. Carcinogenesis, 2010-11-03;32(2):129-37. 2010-11-03 [PMID: 21051441] (Flow Cytometry, Human) Flow Cytometry Human

Review for SOX2 Antibody (IC2018A) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using IC2018A:
Filter by Applications
Flow
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
  4
reviewed by:
Verified Customer
 Flow Human 01/27/2015
View

Summary

ApplicationFlow Cytometry
Sample TestedSee PMID: 23264559
SpeciesHuman

FAQs for SOX2 Antibody (IC2018A) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

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By Jamshed Arslan Pharm.D. Multiple myeloma (MM) is a cancer of antibody-producing plasma cells. The bone marrow (BM) of MM patients is hypoxic, and MM cells overexpress many cancerous genes that are regulated by hy...  Read full blog post.
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SOX2 - a stem cell transcription factor
The SOX gene family encodes a group of highly conserved transcription factors defined by the presence of a conserved high motility group (HMG) DNA-binding domain. They are involved in embryonic development regulation and cell fate determination. Al...  Read full blog post.
SOX2: an Important Stem Cell Transcription Factor
SOX2 is a transcription factor that is expressed by self-renewing and multipotent stem cells of the embryonic neuroepithelium. Sox-2 was found to be expressed by dividing neural progenitor cells. Constitutive expression of SOX2 has also been shown to ...  Read full blog post.
Sox2 and Oct4: Roles in Embryonic Stem Cell Pluripotency
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Recent Reviews

4
5
0
4
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3
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2
0
1
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 Verified Customer
01/27/2015
Application: Flow
Species: Human
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Bioinformatics

Gene Symbol SOX2
Uniprot