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SmarcAL1 Antibody (PCRP-SMARCAL1-1C4) [DyLight 755]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PCRP-SMARCAL1-1C4
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 755

Order Details

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SmarcAL1 Antibody (PCRP-SMARCAL1-1C4) [DyLight 755] Summary

Immunogen
Recombinant full-length human SmarcAL1 protein
Localization
Nucleus.
Isotype
IgG2c Kappa
Clonality
Monoclonal
Host
Mouse
Gene
SMARCAL1
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SmarcAL1 Antibody (PCRP-SMARCAL1-1C4) [DyLight 755]

  • ATP-driven annealing helicase
  • EC 3.6.1
  • EC 3.6.4.-
  • HARPSWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A-like protein 1
  • HepA-related protein
  • HHARP
  • SIOD
  • SMARCA-like protein 1
  • subfamily a-like 1
  • Sucrose nonfermenting protein 2-like 1
  • SWI/SNF related, matrix associated, actin dependent regulator of chromatin

Background

SmarcAL1 is encoded by this gene is a member of the SWI/SNF family of proteins. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein shows sequence similarity to the E. coli RNA polymerase-binding protein HepA. Mutations in this gene are a cause of Schimke immunoosseous dysplasia (SIOD), an autosomal recessive disorder with the diagnostic features of spondyloepiphyseal dysplasia, renal dysfunction, and T-cell immunodeficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SMARCAL1