Sirtuin 1/SIRT1 Antibody (834918) [mFluor Violet 500 SE] Summary
Immunogen |
E. coli-derived recombinant human Sirtuin 1/SIRT1 Met1-Ser747 Accession # Q96EB6 |
Specificity |
Detects human Sirtuin 1/SIRT1 in ELISAs.
In direct ELISAs, no cross-reactivity
with recombinant human Sirtuin 2, 3, 5, or 6 is observed. |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
SIRT1 |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- CyTOF-ready
- Immunocytochemistry
- Intracellular Staining by Flow Cytometry
|
Application Notes |
Optimal dilution of this antibody should be experimentally determined. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
50mM Sodium Borate |
Preservative |
0.05% Sodium Azide |
Notes
mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.
Alternate Names for Sirtuin 1/SIRT1 Antibody (834918) [mFluor Violet 500 SE]
Background
The S. cerevisiae silent information regulator 2 (Sir2) protein is an NAD+-dependent histone deacetylase (HDACs) that plays a critical role in transcriptional silencing, genome stability, and longevity (1-2). Part of the Sirtuin family (Sir2, Sir3, Sir3), yeast Sir2 is the founding member of Class III HDACs. A human homologue of Sir2 , SIRT1, regulates the activity of the p53 tumor suppressor and inhibits apoptosis (3-4).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for Sirtuin 1/SIRT1 Antibody (FAB7714MFV500) (0)
Secondary Antibodies
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Isotype Controls
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