SF3B4 Antibody (3A1) [FITC] Summary
Description |
This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet. |
Immunogen |
Full length recombinant human SF3B4 expressed in and purified from E. coli. [UniProt# Q15427] |
Localization |
Nucleus. |
Isotype |
IgG2b |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
SF3B4 |
Purity |
Protein G purified |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunocytochemistry/ Immunofluorescence
- Immunohistochemistry
- Western Blot
|
Application Notes |
This SF3B4 (3A1) antibody is useful for Immunocytochemistry/Immunofluorescence and Western blot, where a band can be seen at approximately 49 kDa.
The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors. |
Packaging, Storage & Formulations
Storage |
Store at 4C in the dark. |
Buffer |
PBS |
Preservative |
0.05% Sodium Azide |
Purity |
Protein G purified |
Alternate Names for SF3B4 Antibody (3A1) [FITC]
Background
SF3B4 (splicing factor 3B subunit 4, also known as SF3b50 or SAP49), is a ubiquitously expressed nuclear protein which forms a subunit of splicing factor SF3B (SF3B1/SAP155/SF3B155, SF3B2/SAP145/SF3B145, SF3B3/SAP130/SF3B130, SF3B4/SAP49/SF3B49, SF3B14A, PHF5A/SF3B14B, SF3B10 and SF3B125) required for 'A' complex assembly formed by the stable binding of U2 snRNP to pre-mRNA's BPS (branchpoint sequence). SF3B4 interacts directly with SF3B2 and also forms a component of U11/U12 snRNPs that are a part of the U12-type spliceosome. SF3B4 has also been suggested to implicate in 'E' complex assembly and is also found in 'B' and 'C' complexes. SF3B4 is also associated with minor U12-dependent spliceosome, which is involved in the splicing of rare class of nuclear pre-mRNA intron. Defects in SF3B4 have been linked to AFD1 (acrofacial dysostosis type 1) which is a form of acrofacial dysostosis, a group of disorders characterized by malformation of the craniofacial skeleton and limbs.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
Customers Who Viewed This Item Also Viewed...
Species: Hu
Applications: IHC, IHC-P, IP, WB
Species: Hu, Mu
Applications: ELISA, ICC/IF, IHC, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: ICC/IF, IHC, IHC-P, IP, WB
Species: Mu, Rt
Applications: ELISA, ICC/IF, IHC, IHC-Fr, IHC-P, WB
Species: Hu, Mu
Applications: IHC, IHC-P, WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ELISA, IHC, IHC-Fr, PEP-ELISA, WB
Species: Hu, Mu, Rt
Applications: WB
Species: Hu, Mu
Applications: ICC/IF, IHC, IHC-P
Species: Mu
Applications: ICC, IHC, Simple Western, WB
Species: Hu
Applications: Flow, ICC/IF, PA
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu
Applications: ELISA, S-ELISA, WB
Species: Hu
Applications: ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Pm, Rt, Xp, Ze
Applications: ELISA, Flow, ICC/IF, IHC, IHC-P, IP, WB
Species: Hu
Applications: ELISA, ICC/IF, IHC, IHC-P, WB
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Publications for SF3B4 Antibody (NBP1-92692F) (0)
There are no publications for SF3B4 Antibody (NBP1-92692F).
By submitting your publication information earn gift cards and discounts for future purchases.
Reviews for SF3B4 Antibody (NBP1-92692F) (0)
There are no reviews for SF3B4 Antibody (NBP1-92692F).
By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
- Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
- Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Video Protocols
FAQs for SF3B4 Antibody (NBP1-92692F) (0)
Secondary Antibodies
| |
Isotype Controls
|
Additional SF3B4 Products
Research Areas for SF3B4 Antibody (NBP1-92692F)
Find related products by research area.
|
Blogs on SF3B4