| Reactivity | MuSpecies Glossary |
| Applications | WB |
| Clonality | Polyclonal |
| Host | Goat |
| Conjugate | Unconjugated |
| Concentration | LYOPH |
| Immunogen | Mouse myeloma cell line NS0-derived recombinant mouse Serpin I1 |
| Specificity | Detects mouse Serpin I1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 50% cross-reactivity with recombinant human (rh) Serpin I1 is observed and less than 5% cross‑reactivity with rhSerpin I2is observed. |
| Source | N/A |
| Isotype | IgG |
| Clonality | Polyclonal |
| Host | Goat |
| Gene | SERPINI1 |
| Purity Statement | Antigen Affinity-purified |
| Innovator's Reward | Test in a species/application not listed above to receive a full credit towards a future purchase. |
| Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
|
| Buffer | Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
| Preservative | No Preservative |
| Concentration | LYOPH |
| Reconstitution Instructions | Reconstitute at 0.2 mg/mL in sterile PBS. |
Serpin I1 (serine proteinase inhibitor-clade I 1; also protease inhibitor 17 and neuroserpin) is a 52 kDa member of the serpin superfamily of protease inhibitors. It is a component of dense-core secretory granules in neurons of the cerebellum, hippocampus and hypothalamus and following release shows inhibitory activity towards tissue-type plasminogen activator. The mouse Serpin I1 precursor is 410 amino acids (aa) in length. It contains a 16 aa signal sequence plus a reactive center loop that lies between Gly348 and Pro375. Mature mouse Serpin I1 (aa 17‑410) shares 88% and 92% aa identity with human and rat Serpin I1, respectively.
![Knockout Validated SerpinB2 Antibody (930109) [Unconjugated]](https://images.novusbio.com/images2/Serpin_B2_MAB8550_Knockout_Validated_21056.jpg)
![Immunocytochemistry SerpinB2 Antibody (930109) [Unconjugated]](https://images.novusbio.com/images2/Serpin_B2_MAB8550_Immunocytochemistry__Immunofluorescence_17162.jpg)
![Western Blot SerpinB2 Antibody (930109) [Unconjugated]](https://images.novusbio.com/images2/Serpin_B2_MAB8550_Western_Blot_17242.jpg)
![Serpin I1/Neuroserpin Antibody [Unconjugated]](/sites/all/modules/enterprise-tech/et_datasheets/images/novus_guarantee.png "Serpin I1/Neuroserpin Antibody [Unconjugated]")
Secondary Antibodies |
Isotype Controls |
The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.
| Gene Symbol | SERPINI1 |
![N/A t-Plasminogen Activator/tPA [HRP]](https://images.novusbio.com/images2/DATA_tPlasminogen_Activator_DTPA00_ELISA_854.jpg)
![N/A t-Plasminogen Activator/tPA [HRP]](https://images.novusbio.com/images2/tPlasminogen_Activator_DTPA00_ELISA_510.jpg)
![Enzyme Activity u-Plasminogen Activator/Urokinase [Unconjugated]](https://images.novusbio.com/images2/uPlasminogen_Activator_1310SE_1837.jpg)
![Western Blot Serpin A1/alpha 1-Antitrypsin Antibody (202808) [Unconjugated]](https://images.novusbio.com/images2/Serpin_A1_MAB1268_Western_Blot_17309.jpg)
![Simple Western Serpin A1/alpha 1-Antitrypsin Antibody (202808) [Unconjugated]](https://images.novusbio.com/images2/Serpin_A1_MAB1268_Immunocytochemistry__Immunofluorescence_17494.jpg)
![Immunocytochemistry Serpin A1/alpha 1-Antitrypsin Antibody (202808) [Unconjugated]](https://images.novusbio.com/images2/Serpin_A1_MAB1268_Immunocytochemistry_11973.jpg)
