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Serpin A8/Angiotensinogen Antibody Pair [HRP]

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Sandwich ELISA: Serpin A8/Angiotensinogen Antibody Pair [HRP] [NBP2-79330] - This standard curve is only for demonstration purposes. A standard curve should be generated for each assay.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications ELISA
Conjugate
HRP
Standard Curve Range
234.38-15000 pg/ml (example only; lot dependent)
Sensitivity
234.375 pg/ml (example only; lot dependent)

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Catalog# & Conjugate Size Price
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Serpin A8/Angiotensinogen Antibody Pair [HRP] Summary

Description
Solid Phase sandwich ELISA for the quantitative determination of Human Serpin A8/Angiotensinogen.
Specificity
This solid phase sandwich ELISA utilizes an antibody specific for Human Serpin A8/Angiotensinogen.
Standard Curve Range
234.38-15000 pg/ml (example only; lot dependent)
Sensitivity
234.375 pg/ml (example only; lot dependent)
Assay Type
Sandwich ELISA
Sample Volume
100 ul
Gene
AGT

Applications/Dilutions

Dilutions
  • ELISA
  • Sandwich ELISA

Packaging, Storage & Formulations

Storage
Storage of components varies. See protocol for specific instructions.

Kit Components

Components
  1. Mouse Monoclonal Capture Antibody
  2. Rabbit Polyclonal Detection Antibody (HRP-conjugated)
  3. Standard

Alternate Names for Serpin A8/Angiotensinogen Antibody Pair [HRP]

  • AGT
  • alpha-1 antiproteinase, antitrypsin
  • Angiotensin II
  • angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
  • Angiotensinogen
  • ANHU
  • Aogen
  • FLJ92595
  • FLJ97926
  • PAT
  • pre-angiotensinogen
  • serine (or cysteine) proteinase inhibitor
  • Serpin A8
  • SERPINA8angiotensin I

Background

Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

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Bioinformatics

Gene Symbol AGT