Serpin A8/Angiotensinogen Antibody Pair [HRP] Summary
Description |
Solid Phase sandwich ELISA for the quantitative determination of Human Serpin A8/Angiotensinogen. |
Specificity |
This solid phase sandwich ELISA utilizes an antibody specific for Human Serpin A8/Angiotensinogen. |
Standard Curve Range |
234.38-15000 pg/ml (example only; lot dependent) |
Sensitivity |
234.375 pg/ml (example only; lot dependent) |
Assay Type |
Sandwich ELISA |
Sample Volume |
100 ul |
Gene |
AGT |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
Components
|
- Mouse Monoclonal Capture Antibody
- Rabbit Polyclonal Detection Antibody (HRP-conjugated)
- Standard
|
Alternate Names for Serpin A8/Angiotensinogen Antibody Pair [HRP]
Background
Angiotensin II is encoded by this gene, pre-angiotensinogen or angiotensinogen precursor, is expressed in the liver and is cleaved by the enzyme renin in response to lowered blood pressure. The resulting product, angiotensin I, is then cleaved by angiotensin converting enzyme (ACE) to generate the physiologically active enzyme angiotensin II. The protein is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Mutations in this gene are associated with susceptibility to essential hypertension, and can cause renal tubular dysgenesis, a severe disorder of renal tubular development. Defects in this gene have also been associated with non-familial structural atrial fibrillation, and inflammatory bowel disease.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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