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SERCA2 ATPase Antibody (IID8) [Biotin]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Am, Bv, Ca, Gp, Ha, Pm, Rb, Sh, V-ViSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, B/N
Clone
IID8
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NB300-529AF350
Alexa Fluor 405
NB300-529AF405
Alexa Fluor 488
NB300-529AF488
Alexa Fluor 532
NB300-529AF532
Alexa Fluor 594
NB300-529AF594
Alexa Fluor 647
NB300-529AF647
Alexa Fluor 700
NB300-529AF700
Alexa Fluor 750
NB300-529AF750
Allophycocyanin
NB300-529APC
DyLight 350
NB300-529UV
DyLight 405
NB300-529V
DyLight 488
NB300-529G
DyLight 550
NB300-529R
DyLight 594
NB300-529DL594
DyLight 650
NB300-529C
DyLight 680
NB300-529FR
DyLight 755
NB300-529IR
FITC
NB300-529F
HRP
NB300-529H
Janelia Fluor 549
NB300-529JF549
Janelia Fluor 646
NB300-529JF646
PE
NB300-529PE
Unconjugated
NB300-529
mFluor Violet 450 SE
NB300-529MFV450
mFluor Violet 500 SE
NB300-529MFV500
mFluor Violet 610 SE
NB300-529MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB300-529
BSA Free
NB300-529
BSA Free
NB300-529-0.025ml
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SERCA2 ATPase Antibody (IID8) [Biotin] Summary

Immunogen
Purified canine cardiac sarcoplasmic reticulum.
Specificity
Detects Sarcoplasmic or Endoplasmic Reticulum Calcium 2 (SERCA2) ATPase. This does not discriminate between the two isoforms.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ATP2A2
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Block/Neutralize
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for SERCA2 ATPase Antibody (IID8) [Biotin]

  • ATP2A2
  • ATP2B
  • ATP2BFLJ20293
  • ATPase, Ca++ dependent, slow-twitch, cardiac muscle-2
  • ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
  • Calcium pump 2
  • Calcium-transporting ATPase sarcoplasmic reticulum type, slow twitch skeletalmuscle isoform
  • cardiac Ca2+ ATPase
  • DAR
  • DD
  • EC 3.6.3
  • EC 3.6.3.8
  • Endoplasmic reticulum class 1/2 Ca(2+) ATPase
  • FLJ38063
  • MGC45367
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 2
  • SERCA2 ATPase
  • SERCA2
  • SERCA2DKFZp686P0211
  • SR Ca(2+)-ATPase 2

Background

Sarcoplasmic/endoplasmic reticulum Calcium-ATPase 2 (SERCA2) is a magnesium-dependent pump that catalyzes the hydrolysis of ATP and translocates calcium from the cytosol to the sarcoplasmic reticulum lumen. There are 2 SERCA2 isoforms that differ in the 3' UTR. The SERCA2A isoform is highly expressed in heart and slow twitch skeletal muscle and is important to the regulation of the contraction and relaxation cycle, while the SERCA2B isoform is expressed in smooth muscle and adult epidermis. SERCA2 is also known as ATP2A2, ATP2B, DAR, DD, and MGC45367.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol ATP2A2