SEC62 Antibody

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. (provided by RefSeq)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Canine.

We have publications tested in 1 application: WB.

Showing Publications 1 - 6 of 6.

Publications using NBP1-84045	Applications	Species
Ishii S, Chino H, Ode KL et al. CCPG1 recognizes ER luminal proteins for selective ER-phagy Molecular biology of the cell 2023-02-03 [PMID: 36735498] (WB, Human)	WB	Human
Kennedy A, Ren HY, Madden VJ, Cyr DM. Lysosome docking to WIPI1 rings and ER-connected phagophores occurs during DNAJB12- and GABARAP-dependent selective autophagy of misfolded P23H-rhodopsin Molecular Biology of the Cell 2022-08-01 [PMID: 35704470]
Lihua H, Andrew K, Scott H et al. DNAJB12 and Hsp70 Triage Arrested Intermediates of N1303K-CFTR for ER Associated-Autophagy. Mol Biol Cell. 2021-02-03 [PMID: 33534640]
Chino, H;Hatta, T;Natsume, T;Mizushima, N; Intrinsically Disordered Protein TEX264 Mediates ER-phagy Mol. Cell 2019-04-11 [PMID: 31006538] (WB, Human)	WB	Human
Bhalchandra Jadhav, Michael McKenna, Nicholas Johnson et al. Mammalian SRP receptor switches the Sec61 translocase from Sec62 to SRP-dependent translocation. Nature Communications 2015-01-01 [PMID: 26634806] (WB, Canine)	WB	Canine
Hagerstrand D, Tong A, Schumacher SE et al. Systematic interrogation of 3q26 identifies TLOC1 and SKIL as cancer drivers. Cancer Discov 2013-09-01 [PMID: 23764425] (WB)	WB

Array NBP1-84045

• SEC62 Antibodies
• SEC62 Lysate
• SEC62 Proteins