RTN1-A/NSP Antibody (559706) [Unconjugated] Summary
Immunogen |
E. coli-derived recombinant rat RTN1-A/NSP Met73-Ser502 Accession # Q64548 |
Specificity |
Detects rat RTN1-A/NSP in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant rat RTN-A2B, recombinant human (rh) RTN1-A, and rhRTN3-A1 is observed. |
Source |
N/A |
Isotype |
IgG1 |
Clonality |
Monoclonal |
Host |
Mouse |
Gene |
Rtn1 |
Purity Statement |
Protein A or G purified from hybridoma culture supernatant |
Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
Dilutions |
- Immunohistochemistry 8-25 ug/mL
|
Packaging, Storage & Formulations
Storage |
Use a manual defrost freezer and avoid repeated freeze-thaw cycles. - 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
|
Buffer |
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS. |
Preservative |
No Preservative |
Concentration |
LYOPH |
Reconstitution Instructions |
Reconstitute at 0.5 mg/mL in sterile PBS. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for RTN1-A/NSP Antibody (559706) [Unconjugated]
Background
Reticulon-1 (RTN1-A/RTN1) is a 135 kDa multi-pass membrane protein localized to the endoplasmic reticulum of neurons. RTN1-A belongs to no known family of proteins. Rat RTN1-A is 777 amino acids (aa) in length and contains two transmembrane segments and a Reticulon domain (aa 592-759). There are also multiple potential sites for phosphorylation. Alternative splicing produces a second isoform known as RTN1-S, which is missing residues corresponding to aa 1-569 in RTN1-A, and has a 20 aa substitution for residues corresponding to aa 570-589. Rat RTN1-A is 82% aa identical to human RTN1-A
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for RTN1-A/NSP Antibody (MAB5996) (0)
Secondary Antibodies
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