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RSK4 Antibody

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Immunocytochemistry/Immunofluorescence: RSK4 Antibody [NBP1-87108] - Staining of human cell line RH-30 shows localization to nucleoli fibrillar center & mitochondria. Antibody staining is shown in green.
Immunocytochemistry/ Immunofluorescence: RSK4 Antibody [NBP1-87108] - Staining of human cell line RH-30 shows localization to nucleoli fibrillar center & mitochondria. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: RSK4 Antibody [NBP1-87108] - Staining of human stomach shows strong cytoplasmic and membranous positivity in glandular cells.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

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RSK4 Antibody Summary

Immunogen
This antibody was developed against Recombinant Protein corresponding to amino acids: PFKPASGKPDDTFCFDPEFTAKTPKDSPGLPASANAHQLFKGFSFVATSIAEEYKITPITSANVLPIVQINGNAAQFGEVYELKEDIGVGSYSVCKRCIHATTNMEFAVKIIDKSK
Predicted Species
Mouse (91%), Rat (91%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RPS6KA6
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
Control Peptide
RSK4 Protein (NBP1-87108PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RSK4 Antibody

  • EC 2.7.11
  • EC 2.7.11.1
  • p90-RSK 6
  • p90RSK6
  • pp90RSK4
  • PP90RSK4,90 kDa ribosomal protein S6 kinase 6
  • ribosomal protein S6 kinase alpha-6
  • ribosomal protein S6 kinase, 90kDa, polypeptide 6
  • Ribosomal S6 kinase 4
  • RPS6KA6
  • RSK4
  • RSK-4
  • RSK4ribosomal protein S6 kinase, 90kD, polypeptide 6
  • S6K-alpha 6
  • S6K-alpha-6

Background

RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RPS6KA6