RSK4 Products

Description

RSK4 is a member of the family of 90-kDa ribosomal S6 kinases (1). These proteins are a class of serine/threonine kinases that are activated in response to various extracellular signals, including growth factors, polypeptide hormones and neurotransmitters (2). RSK4 is most abundantly expressed in brain and kidney. The predicted protein of 746 amino acids shows a high level of homology to three previously isolated members of the human RSK family. RSK2 is involved in Coffin-Lowry syndrome and nonspecific MRX. The localization of RSK4 in the interval that is commonly deleted in mentally retarded males together with the high degree of amino acid identity with RSK2 suggests that RSK4 plays a role in normal neuronal development (3).

Bioinformatics

Entrez	27330 Human
Uniprot	NM_014496 Human NP_055311 Human NP_055311.1 Human Q9UK32 Human
Product By Gene ID	27330
Alternate Names	EC 2.7.11 EC 2.7.11.1 p90-RSK 6 p90RSK6 pp90RSK4 PP90RSK4,90 kDa ribosomal protein S6 kinase 6 ribosomal protein S6 kinase alpha-6 ribosomal protein S6 kinase, 90kDa, polypeptide 6 Ribosomal S6 kinase 4 RSK-4 RSK4ribosomal protein S6 kinase, 90kD, polypeptide 6 S6K-alpha 6 S6K-alpha-6

Research Areas for RSK4

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase