RNA Helicase A Antibody

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein with RNA helicase activity. It may participate in melting of DNA:RNA hybrids, such as those that occur during transcription, and may play a role in X-linked gene expression. It contains 2 copies of a double-stranded RNA-binding domain, a DEXH core domain and an RGG box. The RNA-binding domains and RGG box influence and regulate RNA helicase activity. [provided by RefSeq]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: ICC/IF, IP, KD, RIP, WB.

Showing Publications 1 - 7 of 7.

Publications using NB110-40579	Applications	Species
Xia A, Yue Q, Zhu M et al. The cancer-testis lncRNA LINC01977 promotes HCC progression by interacting with RBM39 to prevent Notch2 ubiquitination Cell death discovery 2023-05-18 [PMID: 37198207] (RIP, Human)	RIP	Human
Xia A, Yuan W, Wang Q et al. The cancer-testis lncRNA lnc-CTHCC promotes hepatocellular carcinogenesis by binding hnRNP K and activating YAP1 transcription Nature Cancer 2022-01-10 [PMID: 35122073] (RIP, Human)	RIP	Human
Dempsey A, Keating SE, Carty M et al. Poxviral protein E3-altered cytokine production reveals that DExD/H-box helicase 9 controls Toll-like receptor-stimulated immune responses J. Biol. Chem. 2018-08-15 [PMID: 30111593] (WB, IP, KD, Human)	WB, IP, KD	Human
Moldovan JB, Moran JV. The Zinc-Finger Antiviral Protein ZAP Inhibits LINE and Alu Retrotransposition. PLoS Genet 2015-05-01 [PMID: 25951186] (WB, ICC/IF, Human)	WB, ICC/IF	Human
Maxwell SS, Pelka GJ, Tam PP, El-Osta A. Chromatin context and ncRNA highlight targets of MeCP2 in brain. RNA Biol 2013-11-01 [PMID: 24270455] (Mouse)		Mouse
Watashi K, Yeung ML, Starost MF et al. Identification of small molecules that suppress microRNA function and reverse tumorigenesis. J Biol Chem 2010-08-01 [PMID: 20529860]
Lawrence P, Rieder E. Identification of RNA helicase A as a new host factor in the replication cycle of foot-and-mouth disease virus. J Virol 2009-11-01 [PMID: 19710149]

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Verified Customer	ICC	Human	03/03/2020	View Summary Application Immunocytochemistry Sample Tested 293T lysate,Human Cell lines Species Human Lot A2

Array NB110-40579

• RNA Helicase A Antibodies
• RNA Helicase A Proteins