Immunocytochemistry/ Immunofluorescence: RFC1 Antibody [NBP2-54960] - Staining of human cell line U-2 OS shows localization to nucleoplasm. Antibody staining is shown in green.
This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: QDVVALMDTYYLMKEDFENIMEISSWGGKPSPFSKLDPKVKAAFTRAYNKEAHLTPYSLQAIKASRHSTSPSLDSEYNEELNEDDSQSDEKDQDAI
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RFC1
Purity
Affinity purified
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.2) and 40% Glycerol
Preservative
0.02% Sodium Azide
Purity
Affinity purified
Alternate Names for RFC1 Antibody - BSA Free
A1 140 kDa subunit
A1
Activator 1 140 kDa subunit
Activator 1 large subunit
Activator 1 subunit 1
MGC51786
MHC binding factor, beta
MHCBFB
PO-GA
RECC1
replication factor C (activator 1) 1 (145kD)
replication factor C (activator 1) 1, 145kDa
Replication factor C 140 kDa subunit
Replication factor C large subunit
replication factor C subunit 1
replication factor C1
RF-C 140 kDa subunit
RFC
RFC1
RFC140
RFC140DNA-binding protein PO-GA
Background
RFC1 is encoded by this gene is the large subunit of replication factor C, which is a five subunit DNA polymerase accessory protein. Replication factor C is a DNA-dependent ATPase that is required for eukaryotic DNA replication and repair. The protein acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It also may have a role in telomere stability. [provided by RefSeq]
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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