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Recombinant Human TIMP-1 Western Blot Standard Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Format
Carrier-Free

Order Details

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Recombinant Human TIMP-1 Western Blot Standard Protein Summary

Protein/Peptide Type
Recombinant Enzymes
Gene
TIMP1

Applications/Dilutions

Dilutions
  • Western Blot
Publications
Read Publication using WBC021.

Packaging, Storage & Formulations

Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human TIMP-1 Western Blot Standard Protein

  • CLGI
  • Collagenase inhibitor
  • collagenase inhibitor)
  • EPATIMP-1
  • EPO
  • erythroid potentiating activity
  • Erythroid-potentiating activity
  • Fibroblast collagenase inhibitor
  • FLJ90373
  • HCI
  • metalloproteinase inhibitor 1
  • TIMP metallopeptidase inhibitor 1
  • TIMP1
  • TIMP-1
  • TIMPtissue inhibitor of metalloproteinase 1 (erythroid potentiating activity
  • Tissue inhibitor of metalloproteinases 1

Background

TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIMP-1 and TIMP-2 binds to the hemopexin- like domain of pro-MMP-9 and pro-MMP-2, respectively. The latter binding is essential for the cell surface activation of MMP-2 by MMP-14.

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Publications for TIMP-1 (WBC021)(1)

We have publications tested in 1 application: Dot Blot.


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Dot Blot
(1)
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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for TIMP-1 (WBC021) (0)

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Additional TIMP-1 Products

Blogs on TIMP-1

There are no specific blogs for TIMP-1, but you can read our latest blog posts.
Read our latest blog and use the new citation tool on bio-techne.com

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Bioinformatics

Gene Symbol TIMP1