| L Feige, T Kozaki, G Dias de Me, V Guillemot, F Larrous, F Ginhoux, H Bourhy Susceptibilities of CNS Cells towards Rabies Virus Infection Is Linked to Cellular Innate Immune Responses Viruses, 2022-12-29;15(1):. 2022-12-29 [PMID: 36680128] (Bioassay, Human) |
Bioassay |
Human |
| Y Fukawa, K Kayamori, M Tsuchiya, T Ikeda IL-1 Generated by Oral Squamous Cell Carcinoma Stimulates Tumor-Induced and RANKL-Induced Osteoclastogenesis: A Possible Mechanism of Bone Resorption Induced by the Infiltration of Oral Squamous Cell Carcinoma International Journal of Molecular Sciences, 2022-12-30;24(1):. 2022-12-30 [PMID: 36614130] (Cell Culture, Mouse) |
Cell Culture |
Mouse |
| MS Ågren, T Litman, JO Eriksen, P Schjerling, M Bzorek, LMR Gjerdrum Gene Expression Linked to Reepithelialization of Human Skin Wounds International Journal of Molecular Sciences, 2022-12-12;23(24):. 2022-12-12 [PMID: 36555389] (cell cutlure, Human) |
cell cutlure |
Human |
| X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia Embo Molecular Medicine, 2022-12-01;0(0):e15631. 2022-12-01 [PMID: 36453131] (Cell Culture, Human) |
Cell Culture |
Human |
| Kunitomi A, Hirohata R, Arreola V, Osawa M, Kato T, Nomura M, Kawaguchi J, Hara H, Kusano K, Takashima Y, Takahashi K, Fukuda K, Takasu N, Yamanaka S Improved Sendai viral system for reprogramming to naive pluripotency. Cell Rep Methods, 2022-10-17;2(11):100317. 2022-10-17 [PMID: 36447645] (Bioassay, Human) |
Bioassay |
Human |
| M Tayyab, P Xie, MA Sami, H Raji, Z Lin, Z Meng, SR Mahmoodi, M Javanmard A portable analog front-end system for label-free sensing of proteins using nanowell array impedance sensors Scientific Reports, 2022-11-22;12(1):20119. 2022-11-22 [PMID: 36418852] (ELISA Standard, Human) |
ELISA Standard |
Human |
| AKO Rode, TB Buus, V Mraz, FAH Al-Jaberi, DV Lopez, SL Ford, S Hennen, IP Eliasen, IV Klewe, L Gharehdagh, A Dragan, MM Rosenkilde, A Woetmann, L Skov, N Ødum, CM Bonefeld, M Kongsbak-W, C Geisler Induced Human Regulatory T Cells Express the Glucagon-like Peptide-1 Receptor Cells, 2022-08-19;11(16):. 2022-08-19 [PMID: 36010663] (Stimulation, Human) |
Stimulation |
Human |
| YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells Science Advances, 2022-08-24;8(34):eabn5522. 2022-08-24 [PMID: 36001668] (Bioassay, Human) |
Bioassay |
Human |
| MY Wang, CM Zhang, HH Zhou, ZB Ge, CC Su, ZH Lou, XY Zhang, TT Xu, SY Li, L Zhu, YL Zhou, Y Wu, SR Ji Identification of a distal enhancer that determines the expression pattern of acute phase marker C-reactive protein Oncogene, 2022-06-17;0(0):102160. 2022-06-17 [PMID: 35724961] (Bioassay, Human) |
Bioassay |
Human |
| P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells Cancers, 2022-03-11;14(6):. 2022-03-11 [PMID: 35326601] (Cell Culture, Human) |
Cell Culture |
Human |
| A Dritsoula, L Dowsett, C Pilotti, MN O'Connor, SE Moss, J Greenwood Angiopathic activity of LRG1 is induced by the IL-6/STAT3 pathway Scientific Reports, 2022-03-22;12(1):4867. 2022-03-22 [PMID: 35318338] (Bioassay, Human) |
Bioassay |
Human |
| J Whitburn, SR Rao, EV Morris, S Tabata, A Hirayama, T Soga, JR Edwards, Z Kaya, C Palmer, FC Hamdy, CM Edwards Metabolic profiling of prostate cancer in skeletal microenvironments identifies G6PD as a key mediator of growth and survival Science Advances, 2022-02-25;8(8):eabf9096. 2022-02-25 [PMID: 35213227] (Bioassay, Human) |
Bioassay |
Human |
| T Matsumoto, H Okayama, S Nakajima, K Saito, M Ito, A Kaneta, Y Kanke, H Onozawa, S Hayase, S Fujita, W Sakamoto, M Saito, Z Seze, T Momma, K Mimura, K Kono SH2D4A downregulation due to loss of chromosome 8p is associated with poor prognosis and low T cell infiltration in colorectal cancer British Journal of Cancer, 2021-12-10;0(0):. 2021-12-10 [PMID: 34893760] (Bioassay, Human) |
Bioassay |
Human |
| SA Saenz, A Local, T Carr, A Shakya, S Koul, H Hu, L Chourb, J Stedman, J Malley, LA D'Agostino, V Shanmugasu, J Malona, CE Schwartz, L Beebe, M Clements, G Rajaraman, J Cho, L Jiang, A Dubrovskiy, M Kreilein, R Shimanovic, LG Hamann, L Escoubet, JM Ellis Small molecule allosteric inhibitors of RORgammat block Th17-dependent inflammation and associated gene expression in vivo PLoS ONE, 2021-11-09;16(11):e0248034. 2021-11-09 [PMID: 34752458] (Bioassay, Human) |
Bioassay |
Human |
| A Pirosa, EB Tankus, A Mainardi, P Occhetta, L Dönges, C Baum, M Rasponi, I Martin, A Barbero Modeling In Vitro Osteoarthritis Phenotypes in a Vascularized Bone Model Based on a Bone-Marrow Derived Mesenchymal Cell Line and Endothelial Cells International Journal of Molecular Sciences, 2021-09-03;22(17):. 2021-09-03 [PMID: 34502489] (Bioassay, Human) |
Bioassay |
Human |
| G Carbotti, B Dozin, S Martini, C Giordano, F Scordamagl, M Croce, G Filaci, S Ferrini, M Fabbi IL-27 Mediates PD-L1 Expression and Release by Human Mesothelioma Cells Cancers, 2021-08-09;13(16):. 2021-08-09 [PMID: 34439164] (Bioassay, Human) |
Bioassay |
Human |
| AL Fisher, V Sangkhae, K Balušíková, NJ Palaskas, T Ganz, E Nemeth Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy Nature Communications, 2021-06-29;12(1):4026. 2021-06-29 [PMID: 34188052] (Bioassay, Human) |
Bioassay |
Human |
| LG Lima, S Ham, H Shin, EPZ Chai, ESH Lek, RJ Lobb, AF Müller, S Mathivanan, B Yeo, Y Choi, BS Parker, A Möller Tumor microenvironmental cytokines bound to cancer exosomes determine uptake by cytokine receptor-expressing cells and biodistribution Nature Communications, 2021-06-10;12(1):3543. 2021-06-10 [PMID: 34112803] (ELISA Capture, Human) |
ELISA Capture |
Human |
| P Gonzalez-M, M Romano, H Yan, R Deshmukh, J Papoin, L Oburoglu, M Daumur, AS Dumé, I Phadke, C Mongellaz, X Qu, PN Bories, M Fontenay, X An, V Dardalhon, M Sitbon, VS Zimmermann, PG Gallagher, S Tardito, L Blanc, N Mohandas, N Taylor, S Kinet An IDH1-vitamin C crosstalk drives human erythroid development by inhibiting pro-oxidant mitochondrial metabolism Cell Reports, 2021-02-02;34(5):108723. 2021-02-02 [PMID: 33535038] (Bioassay, Human) |
Bioassay |
Human |
| H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses Scientific Reports, 2021-01-21;11(1):1949. 2021-01-21 [PMID: 33479269] (Bioassay, Human) |
Bioassay |
Human |
| KW Zhang, D Wang, H Cai, MQ Cao, YY Zhang, PY Zhuang, J Shen IL?6 plays a crucial role in epithelial?mesenchymal transition and pro?metastasis induced by sorafenib in liver cancer Oncology reports, 2021-01-07;0(0):. 2021-01-07 [PMID: 33432366] (Bioassay, Human) |
Bioassay |
Human |
| J Dong, S Viswanatha, E Adami, BK Singh, SP Chothani, B Ng, WW Lim, J Zhou, M Tripathi, NSJ Ko, SG Shekeran, J Tan, SY Lim, M Wang, PM Lio, PM Yen, S Schafer, SA Cook, AA Widjaja Hepatocyte-specific IL11 cis-signaling drives lipotoxicity and underlies the transition from NAFLD to NASH Nature Communications, 2021-01-04;12(1):66. 2021-01-04 [PMID: 33397952] (Bioassay, Human) |
Bioassay |
Human |
| A Dorronsoro, V Lang, I Ferrin, J Fernández-, L Zabaleta, E Pérez-Ruiz, P Sepúlveda, C Trigueros Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation Scientific Reports, 2020-12-14;10(1):21853. 2020-12-14 [PMID: 33318571] (Bioassay, Human) |
Bioassay |
Human |
| J Stebbing, G Sánchez Ni, M Falcone, S Youhanna, P Richardson, S Ottaviani, JX Shen, C Sommerauer, G Tiseo, L Ghiadoni, A Virdis, F Monzani, LR Rizos, F Forfori, A Avendaño-C, S De Marco, L Carrozzi, F Lena, PM Sánchez-Ju, LG Lacerenza, N Cesira, D Caldevilla, A Perrella, L Niccoli, LS Méndez, D Matarrese, D Goletti, YJ Tan, V Monteil, G Dranitsari, F Cantini, A Farcomeni, S Dutta, SK Burley, H Zhang, M Pistello, W Li, M Mas Romero, F Andrés Pre, RS Simón-Tale, R García-Mol, C Kutter, JH Felce, ZF Nizami, AG Miklosi, JM Penninger, F Menichetti, A Mirazimi, P Abizanda, VM Lauschke JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality Sci Adv, 2021-01-01;0(0):. 2021-01-01 [PMID: 33187978] (Spheroid Culture, Human) |
Spheroid Culture |
Human |
| L Gan, H Shen, X Li, Z Han, Y Jing, X Yang, M Wu, Y Xia Mesenchymal stem cells promote chemoresistance by activating autophagy in intrahepatic cholangiocarcinoma Oncol Rep, 2020-11-06;0(0):. 2020-11-06 [PMID: 33155663] (Cell Culture, Human) |
Cell Culture |
Human |
| SA Sheehan, KL Hamilton, EP Retzbach, P Balachandr, H Krishnan, P Leone, GS Goldberg Evidence that Maackia amurensis seed lectin (MASL) exerts pleiotropic actions on oral squamous cells to inhibit SARS-CoV-2 infection and COVID-19 disease progression Res Sq, 2020-10-23;0(0):. 2020-10-23 [PMID: 33106801] (Bioassay, Human) |
Bioassay |
Human |
| L Gorchs, S Ahmed, C Mayer, A Knauf, C Fernández, M Svensson, R Heuchel, E Rangelova, P Bergman, H Kaipe The vitamin D analogue calcipotriol promotes an anti-tumorigenic phenotype of human pancreatic CAFs but reduces T cell mediated immunity Sci Rep, 2020-10-15;10(1):17444. 2020-10-15 [PMID: 33060625] (Human) |
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Human |
| Q Zhang, Z Yang, Y Ni, H Bai, Q Han, Z Yi, X Yi, YL Agbana, Y Kuang, Y Zhu NF-&kappaB and pSTAT3 synergistically drive G6PD overexpression and facilitate sensitivity to G6PD inhibition in ccRCC Cancer Cell Int, 2020-10-06;20(0):483. 2020-10-06 [PMID: 33041664] (Bioassay, Human) |
Bioassay |
Human |
| M Kurte, AM Vega-Lette, P Luz-Crawfo, F Djouad, D Noël, M Khoury, F Carrión Time-dependent LPS exposure commands MSC immunoplasticity through TLR4 activation leading to opposite therapeutic outcome in EAE Stem Cell Res Ther, 2020-09-25;11(1):416. 2020-09-25 [PMID: 32988406] (Bioassay, Human) |
Bioassay |
Human |
| D Talwar, J Messens, TP Dick A role for annexin A2 in scaffolding the peroxiredoxin 2-STAT3 redox relay complex Nature Communications, 2020-09-09;11(1):4512. 2020-09-09 [PMID: 32908147] (Bioassay, Human) |
Bioassay |
Human |
| JY Hur, GR Frost, X Wu, C Crump, SJ Pan, E Wong, M Barros, T Li, P Nie, Y Zhai, JC Wang, J Tcw, L Guo, A McKenzie, C Ming, X Zhou, M Wang, Y Sagi, AE Renton, BT Esposito, Y Kim, KR Sadleir, I Trinh, RA Rissman, R Vassar, B Zhang, DS Johnson, E Masliah, P Greengard, A Goate, YM Li The innate immunity protein IFITM3 modulates &gamma-secretase in Alzheimer's disease Nature, 2020-09-02;0(0):. 2020-09-02 [PMID: 32879487] (Bioassay, Human) |
Bioassay |
Human |
| MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES) Biomed J, 2020-05-29;0(0):. 2020-05-29 [PMID: 32651134] (Bioassay, Human) |
Bioassay |
Human |
| J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation Cell Rep, 2020-06-30;31(13):107820. 2020-06-30 [PMID: 32610123] (Bioassay, Human) |
Bioassay |
Human |
| L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020-06-19;27(1):125-136.e7. 2020-06-19 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
| L Yang, Y Han, BE Nilsson-Pa, V Gupta, P Wang, X Duan, X Tang, J Zhu, Z Zhao, F Jaffré, T Zhang, TW Kim, O Harschnitz, D Redmond, S Houghton, C Liu, A Naji, G Ciceri, S Guttikonda, Y Bram, DT Nguyen, M Cioffi, V Chandar, DA Hoagland, Y Huang, J Xiang, H Wang, D Lyden, A Borczuk, HJ Chen, L Studer, FC Pan, DD Ho, BR tenOever, T Evans, RE Schwartz, S Chen A Human Pluripotent Stem Cell-based Platform to Study SARS-CoV-2 Tropism and Model Virus Infection in Human Cells and Organoids Cell Stem Cell, 2020;27(1):125-136.e7. 2020 [PMID: 32579880] (Bioassay, Human) |
Bioassay |
Human |
| JL Spivak, A Merchant, DM Williams, O Rogers, W Zhao, A Duffield, LS Resar, AR Moliterno, ZJ Zhao Thrombopoietin is required for full phenotype expression in a JAK2V617F transgenic mouse model of polycythemia vera PLoS ONE, 2020-06-01;15(6):e0232801. 2020-06-01 [PMID: 32479500] (Bioassay, Transgenic Mouse) |
Bioassay |
Transgenic Mouse |
| MF Abas?yan?k, K Wolfe, H Van Phan, J Lin, B Laxman, SR White, PA Verhoef, GM Mutlu, B Patel, S Tay Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes Nat Commun, 2020-05-25;11(1):2607. 2020-05-25 [PMID: 32451375] (Bioassay, Human) |
Bioassay |
Human |
| J Kanasugi, I Hanamura, A Ota, S Karnan, VQ Lam, S Mizuno, M Wahiduzzam, ML Rahman, T Hyodo, H Konishi, S Tsuzuki, Y Hosokawa, A Takami Biallelic loss of FAM46C triggers tumor growth with concomitant activation of Akt signaling in multiple myeloma cells Cancer Sci., 2020-04-09;111(5):1663-1675. 2020-04-09 [PMID: 32176823] (Cell Culture, Human) |
Cell Culture |
Human |
| H Xiang, CP Ramil, J Hai, C Zhang, H Wang, AA Watkins, R Afshar, P Georgiev, MA Sze, XS Song, PJ Curran, M Cheng, JR Miller, D Sun, A Loboda, Y Jia, LY Moy, A Chi, PE Brandish Cancer-associated fibroblasts promote immunosuppression by inducing ROS-generating monocytic MDSCs in lung squamous cell carcinoma Cancer Immunol Res, 2020-02-19;0(0):. 2020-02-19 [PMID: 32075803] (Bioassay, Human) |
Bioassay |
Human |
| T Mang, S Lindemann, A Gigout Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5 Int J Mol Sci, 2020-01-14;21(2):. 2020-01-14 [PMID: 31947660] (Cell Culture, Human) |
Cell Culture |
Human |
| D Parashar, A Geethadevi, MR Aure, J Mishra, J George, C Chen, MK Mishra, A Tahiri, W Zhao, B Nair, Y Lu, LS Mangala, C Rodriguez-, G Lopez-Bere, AKS Camara, M Liang, JS Rader, R Ramchandra, M You, AK Sood, VN Kristensen, GB Mills, S Pradeep, P Chaluvally miRNA551b-3p Activates an Oncostatin Signaling Module for the Progression of Triple-Negative Breast Cancer Cell Rep, 2019-12-24;29(13):4389-4406.e10. 2019-12-24 [PMID: 31875548] (Cell Culture, Human) |
Cell Culture |
Human |
| JS Hook, M Cao, K Weng, N Kinnare, JG Moreland Mycobacterium tuberculosis Lipoarabinomannan Activates Human Neutrophils via a TLR2/1 Mechanism Distinct from Pam3CSK4 J. Immunol., 2019-12-23;0(0):. 2019-12-23 [PMID: 31871022] (ELISA Standard, Human) |
ELISA Standard |
Human |
| D De Silva, Z Zhang, Y Liu, JS Parker, C Xu, L Cai, GG Wang, HS Earp, YE Whang Interaction between androgen receptor and coregulator SLIRP is regulated by Ack1 tyrosine kinase and androgen Sci Rep, 2019-12-09;9(1):18637. 2019-12-09 [PMID: 31819114] (Cell Culture, Human) |
Cell Culture |
Human |
| X Sun, Q Qu, Y Lao, M Zhang, X Yin, H Zhu, Y Wang, J Yang, J Yi, M Hao Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer BMC Cancer, 2019-12-03;19(1):1180. 2019-12-03 [PMID: 31795965] (ELISA Standard, Human) |
ELISA Standard |
Human |
| A Stumpf, T Brandstett, J Hübner, J Rühe Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum PLoS ONE, 2019-12-02;14(12):e0225525. 2019-12-02 [PMID: 31790441] (ELISA Standard, Human) |
ELISA Standard |
Human |
| X Xu, H Fukui, Y Ran, X Wang, Y Inoue, N Ebisudani, H Nishimura, T Tomita, T Oshima, J Watari, H Kiyama, H Miwa The Link between Type III Reg and STAT3-Associated Cytokines in Inflamed Colonic Tissues Mediators Inflamm., 2019-11-06;2019(0):7859460. 2019-11-06 [PMID: 31780871] (Bioassay, Human) |
Bioassay |
Human |
| N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano, XY Qin, S Kojima, J Fujimoto Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation Sci Rep, 2019-11-26;9(1):17558. 2019-11-26 [PMID: 31772282] (IHC-P, Human) |
IHC-P |
Human |
| JY Ko, WS Lian, TC Tsai, YS Chen, CK Hsieh, CW Kuo, FS Wang MicroRNA-29a Mitigates Subacromial Bursa Fibrosis in Rotator Cuff Lesion with Shoulder Stiffness Int J Mol Sci, 2019-11-15;20(22):. 2019-11-15 [PMID: 31731750] (Cell Culture, Human) |
Cell Culture |
Human |
| AT Stefka, D Johnson, S Rosebeck, JH Park, Y Nakamura, AJ Jakubowiak Potent anti-myeloma activity of the TOPK inhibitor OTS514 in pre-clinical models Cancer Med, 2019-11-12;0(0):. 2019-11-12 [PMID: 31714026] (Cell Culture, Human) |
Cell Culture |
Human |
| JE Lee, X Zhong, JY Lee, YJ Surh, HK Na 15-Keto prostaglandin E2 induces heme oxygenase-1 expression through activation of Nrf2 in human colon epithelial CCD 841 CoN cells Arch. Biochem. Biophys., 2019-12-24;0(0):108162. 2019-12-24 [PMID: 31669540] (Bioassay, Human) |
Bioassay |
Human |
| Z Liu, GWD Easson, J Zhao, N Makki, N Ahituv, MJ Hilton, SY Tang, RS Gray Dysregulation of STAT3 signaling is associated with endplate-oriented herniations of the intervertebral disc in Adgrg6 mutant mice PLoS Genet., 2019-10-25;15(10):e1008096. 2019-10-25 [PMID: 31652254] (Bioassay, Mouse) |
Bioassay |
Mouse |
| J Grajcarek, J Monlong, Y Nishinaka-, M Nakamura, M Nagai, S Matsuo, D Lougheed, H Sakurai, MK Saito, G Bourque, K Woltjen Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations Nat Commun, 2019-10-24;10(1):4856. 2019-10-24 [PMID: 31649251] (Bioassay, Human) |
Bioassay |
Human |
| CGJ Moonen, TJ de Vries, P Rijkschroe, PE Poubelle, EA Nicu, BG Loos The Possible Role of Neutrophils in the Induction of Osteoclastogenesis J Immunol Res, 2019-09-15;2019(0):8672604. 2019-09-15 [PMID: 31637266] (Bioassay, Human) |
Bioassay |
Human |
| ER Wonderlich, K Subramania, B Cox, A Wiegand, C Lackman-Sm, MJ Bale, M Stone, R Hoh, MF Kearney, F Maldarelli, SG Deeks, MP Busch, RG Ptak, DA Kulpa Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals PLoS Pathog., 2019-10-14;15(10):e1008074. 2019-10-14 [PMID: 31609991] (Bioassay, Human) |
Bioassay |
Human |
| C Liang, J Li, C Lu, D Xie, J Liu, C Zhong, X Wu, R Dai, H Zhang, D Guan, B Guo, B He, F Li, X He, W Zhang, BT Zhang, G Zhang, A Lu HIF1alpha inhibition facilitates Leflunomide-AHR-CRP signaling to attenuate bone erosion in CRP-aberrant rheumatoid arthritis Nat Commun, 2019-10-08;10(1):4579. 2019-10-08 [PMID: 31594926] (Bioassay, Human) |
Bioassay |
Human |
| HJ Jang, HJ Lim, EJ Park, SJ Lee, S Lee, SW Lee, MC Rho STAT3-inhibitory activity of sesquiterpenoids and diterpenoids from Curcuma phaeocaulis Bioorg. Chem., 2019-09-10;93(0):103267. 2019-09-10 [PMID: 31586702] (Bioassay, Human) |
Bioassay |
Human |
| Y Yang, W Wang, H Chang, Z Han, X Yu, T Zhang Reciprocal regulation of miR-206 and IL-6/STAT3 pathway mediates IL6-induced gefitinib resistance in EGFR-mutant lung cancer cells J. Cell. Mol. Med., 2019-09-10;0(0):. 2019-09-10 [PMID: 31507089] (Bioassay, Human) |
Bioassay |
Human |
| SK Horrevorts, DA Stolk, RV Ven, M Hulst, BVH Hof, S Duinkerken, MH Heineke, W Ma, SA Dusoswa, R Nieuwland, JJ Garcia-Val, AAV Loosdrecht, TD de Gruijl, SJV Vliet, Y van Kooyk Glycan-Modified Melanoma-Derived Apoptotic Extracellular Vesicles as Antigen Source for Anti-Tumor Vaccination Cancers (Basel), 2019-08-28;11(9):. 2019-08-28 [PMID: 31466401] (Bioassay, Human) |
Bioassay |
Human |
| MD McKenzie, M Ghisi, EP Oxley, S Ngo, L Cimmino, C Esnault, R Liu, JM Salmon, CC Bell, N Ahmed, M Erlichster, MT Witkowski, GJ Liu, M Chopin, A Dakic, E Simankowic, G Pomilio, T Vu, P Krsmanovic, S Su, L Tian, TM Baldwin, DA Zalcenstei, L DiRago, S Wang, D Metcalf, RW Johnstone, BA Croker, GI Lancaster, AJ Murphy, SH Naik, SL Nutt, V Pospisil, T Schroeder, M Wall, MA Dawson, AH Wei, H de Thé, ME Ritchie, J Zuber, RA Dickins Interconversion between Tumorigenic and Differentiated States in Acute Myeloid Leukemia Cell Stem Cell, 2019-08-01;25(2):258-272.e9. 2019-08-01 [PMID: 31374198] (Cell Culture, Human) |
Cell Culture |
Human |
| M Nasri, M Ritter, P Mir, B Dannenmann, N Aghaallaei, D Amend, V Makaryan, Y Xu, B Fletcher, R Bernhard, I Steiert, K Hahnel, J Berger, I Koch, B Sailer, K Hipp, C Zeidler, M Klimiankou, B Bajoghli, DC Dale, K Welte, J Skokowa CRISPR/Cas9 mediated ELANE knockout enables neutrophilic maturation of primary hematopoietic stem and progenitor cells and induced pluripotent stem cells of severe congenital neutropenia patients Haematologica, 2019-06-27;0(0):. 2019-06-27 [PMID: 31248972] (Bioassay, Human) |
Bioassay |
Human |
| D Kim, R Chen, M Sheu, N Kim, S Kim, N Islam, EM Wier, G Wang, A Li, A Park, W Son, B Evans, V Yu, VP Prizmic, E Oh, Z Wang, J Yu, W Huang, NK Archer, Z Hu, N Clemetson, AM Nelson, A Chien, GA Okoye, LS Miller, G Ghiaur, S Kang, JW Jones, MA Kane, LA Garza Noncoding dsRNA induces retinoic acid synthesis to stimulate hair follicle regeneration via TLR3 Nat Commun, 2019-06-26;10(1):2811. 2019-06-26 [PMID: 31243280] (Bioassay, Human) |
Bioassay |
Human |
| YL Chang, Z Wang, S Igawa, JE Choi, T Werbel, A Di Nardo Lipocalin 2: A New Antimicrobial in Mast Cells Int J Mol Sci, 2019-05-14;20(10):. 2019-05-14 [PMID: 31091692] (Cell Culture, Human) |
Cell Culture |
Human |
| AK Mishra, D Dingli Metformin inhibits IL-6 signaling by decreasing IL-6R expression on multiple myeloma cells Leukemia, 2019-04-15;0(0):. 2019-04-15 [PMID: 30988378] (Bioassay, Human) |
Bioassay |
Human |
| B Mair, J Tomic, SN Masud, P Tonge, A Weiss, M Usaj, AHY Tong, JJ Kwan, KR Brown, E Titus, M Atkins, KSK Chan, L Munsie, A Habsid, H Han, M Kennedy, B Cohen, G Keller, J Moffat Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies Cell Rep, 2019-04-09;27(2):599-615.e12. 2019-04-09 [PMID: 30970261] (Differentiation, Differentiation, Human) |
Differentiation, Differentiation |
Human |
| J Kristoff, ML Palma, TM Garcia-Bat, C Shen, N Sluis-Crem, P Gupta, CR Rinaldo, RB Mailliard Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1 EBioMedicine, 2019-04-02;0(0):. 2019-04-02 [PMID: 30952614] (Bioassay, Human) |
Bioassay |
Human |
| C Wei, C Yang, S Wang, D Shi, C Zhang, X Lin, Q Liu, R Dou, B Xiong Crosstalk between cancer cells and tumor associated macrophages is required for mesenchymal circulating tumor cell-mediated colorectal cancer metastasis Mol. Cancer, 2019-03-30;18(1):64. 2019-03-30 [PMID: 30927925] (Human) |
|
Human |
| S Sun, X Zhang, M Xu, F Zhang, F Tian, J Cui, Y Xia, C Liang, S Zhou, H Wei, H Zhao, G Wu, B Xu, X Liu, G Yang, Q Wang, L Zhang, Y Gong, C Shao, Y Zou Berberine downregulates CDC6 and inhibits proliferation via targeting JAK-STAT3 signaling in keratinocytes Cell Death Dis, 2019-03-20;10(4):274. 2019-03-20 [PMID: 30894513] (Bioassay, Human) |
Bioassay |
Human |
| T Hochdörfer, C Winkler, K Pardali, J Mjösberg Expression of c-Kit discriminates between two functionally distinct subsets of human type 2 innate lymphoid cells Eur. J. Immunol., 2019-03-28;0(0):. 2019-03-28 [PMID: 30892687] (Bioassay, Human) |
Bioassay |
Human |
| J van Bastel, R Granzier, LM van Roozen, SMJ van Kuijk, AV Lerut, G Beets, M Hadfoune, S Olde Damin, YLJ Vissers Analysis of TNF-? and interleukin-6 in seroma of patients undergoing mastectomy with or without flap fixation: is there a predictive value for seroma formation and its sequelae? Surg Oncol, 2018-11-08;28(0):36-41. 2018-11-08 [PMID: 30851909] (ELISA (Standard), Human) |
ELISA (Standard) |
Human |
| M Suga, T Kondo, K Imamura, R Shibukawa, Y Okanishi, Y Sagara, K Tsukita, T Enami, M Furujo, K Saijo, Y Nakamura, M Osawa, MK Saito, S Yamanaka, H Inoue Generation of a human induced pluripotent stem cell line, BRCi001-A, derived from a patient with mucopolysaccharidosis type I Stem Cell Res, 2019-02-12;36(0):101406. 2019-02-12 [PMID: 30849633] (Bioassay, Human) |
Bioassay |
Human |
| KC Doh, BM Kim, KW Kim, BH Chung, CW Yang Effects of resveratrol on Th17 cell-related immune responses under tacrolimus-based immunosuppression BMC Complement Altern Med, 2019-03-04;19(1):54. 2019-03-04 [PMID: 30832648] (Bioassay, Human) |
Bioassay |
Human |
| X Qin, M Liu, S Zhang, C Wang, T Zhang The role of IL-36? and its regulation in eosinophilic inflammation in allergic rhinitis Cytokine, 2019-03-01;117(0):84-90. 2019-03-01 [PMID: 30831444] (Bioassay, Human) |
Bioassay |
Human |
| H Xu, SJ Xu, SJ Xie, Y Zhang, JH Yang, WQ Zhang, MN Zheng, H Zhou, LH Qu MicroRNA-122 supports robust innate immunity in hepatocytes by targeting the RTKs/STAT3 signaling pathway Elife, 2019-02-08;8(0):. 2019-02-08 [PMID: 30735121] (Bioassay, Human) |
Bioassay |
Human |
| P Potirat, M Wattanapan, V Viprakasit, P Kheolamai, S Issaragris An integration-free iPSC line (MUSIi008-A) derived from a patient with severe hemolytic anemia carrying compound heterozygote mutations in KLF1 gene for disease modeling Stem Cell Res, 2018-12-14;34(0):101344. 2018-12-14 [PMID: 30605837] (Bioassay, Human) |
Bioassay |
Human |
| TA Ahmed, C Adamopoulo, Z Karoulia, X Wu, R Sachidanan, SA Aaronson, PI Poulikakos SHP2 Drives Adaptive Resistance to ERK Signaling Inhibition in Molecularly Defined Subsets of ERK-Dependent Tumors Cell Rep, 2019-01-02;26(1):65-78.e5. 2019-01-02 [PMID: 30605687] (Bioassay, Human) |
Bioassay |
Human |
| S Yamamoto, K Omori, H Mandai, M Nakayama, S Nakagawa, H Kobayashi, T Kunimine, H Yoshimura, K Sakaida, H Sako, S Ibaragi, T Yamamoto, H Maeda, S Suga, S Takashiba Fungal metabolite (+)-terrein suppresses IL-6/sIL-6R-induced CSF1 secretion by inhibiting JAK1 phosphorylation in human gingival fibroblasts Heliyon, 2018-11-26;4(11):e00979. 2018-11-26 [PMID: 30519664] (Bioassay, Human) |
Bioassay |
Human |
| S Tomi?, N Ili?, V Kokol, A Gruden-Mov, D Mihajlovi?, M Beki?, L Sofroni?-M, M ?oli?, D Vu?evi? Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells Int J Nanomedicine, 2018-10-31;13(0):6941-6960. 2018-10-31 [PMID: 30464452] (Bioassay, Human) |
Bioassay |
Human |
| F Charbit-He, B Bègue, A Sierra, S Hanein, MC Stolzenber, Z Li, S Pellegrini, N Garcelon, M Jeanpierre, B Neven, I Loge, C Picard, J Rosain, J Bustamante, M Le Lorc'h, B Pigneur, A Fernandes, F Rieux-Lauc, J Amil Dias, FM Ruemmele, N Cerf-Bensu Copy number variations and founder effect underlying complete IL-10R? deficiency in Portuguese kindreds PLoS ONE, 2018-10-26;13(10):e0205826. 2018-10-26 [PMID: 30365510] (Bioassay, Human) |
Bioassay |
Human |
| U Painuly, V Ramakrishn, T Kimlinger, L Wellik, J Haug, W Gonsalves, L Bi, Z Huang, SV Rajkumar, S Kumar Aurora kinase and FGFR3 inhibition results in significant apoptosis in molecular subgroups of multiple myeloma Oncotarget, 2018-10-02;9(77):34582-34594. 2018-10-02 [PMID: 30349651] (Bioassay, Human) |
Bioassay |
Human |
| M Zhong, Z Huang, L Wang, Z Lin, Z Cao, X Li, F Zhang, H Wang, Y Li, X Ma Malignant Transformation of Human Bronchial Epithelial Cells Induced by Arsenic through STAT3/miR-301a/SMAD4 Loop Sci Rep, 2018-09-05;8(1):13291. 2018-09-05 [PMID: 30185897] (Bioassay, Human) |
Bioassay |
Human |
| X Jin, X He, X Cao, P Xu, Y Xing, S Sui, L Wang, J Meng, W Lu, R Cui, H Ni, M Zhao Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice Haematologica, 2018-06-14;0(0):. 2018-06-14 [PMID: 29903757] (In Vivo, Mouse) |
In Vivo |
Mouse |
| C Gong, J Shen, Z Fang, L Qiao, R Feng, X Lin, S Li Abnormally Expressed JunB Transactivated by IL-6/STAT3 Signaling Promotes Uveal Melanoma Aggressiveness via Epithelial-mesenchymal Transition Biosci. Rep., 2018-07-02;0(0):. 2018-07-02 [PMID: 29899166] (Bioassay, Human) |
Bioassay |
Human |
| JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation Cell Death Dis, 2018-06-04;9(6):665. 2018-06-04 [PMID: 29867198] (Bioassay, Human) |
Bioassay |
Human |
| T Ohno, H Aoki, S Ohno, M Nishihara, A Furusho, S Hiromatsu, H Akashi, Y Fukumoto, H Tanaka Cytokine Profile of Human Abdominal Aortic Aneurysm: Involvement of JAK/STAT Pathway Ann Vasc Dis, 2018-03-25;11(1):84-90. 2018-03-25 [PMID: 29682112] (Bioassay, Human) |
Bioassay |
Human |
| A Beringer, N Thiam, J Molle, B Bartosch, P Miossec Synergistic effect of interleukin-17 and tumor necrosis factor-α on inflammatory response in hepatocytes through interleukin-6 dependent and independent pathways Clin. Exp. Immunol., 2018-05-31;0(0):. 2018-05-31 [PMID: 29676779] (Bioassay, Human) |
Bioassay |
Human |
| M Cesana, MH Guo, D Cacchiarel, L Wahlster, J Barragan, S Doulatov, LT Vo, B Salvatori, C Trapnell, K Clement, P Cahan, KM Tsanov, PM Sousa, B Tazon-Vega, A Bolondi, FM Giorgi, A Califano, JL Rinn, A Meissner, JN Hirschhorn, GQ Daley A CLK3-HMGA2 Alternative Splicing Axis Impacts Human Hematopoietic Stem Cell Molecular Identity throughout Development Cell Stem Cell, 2018-04-05;22(4):575-588.e7. 2018-04-05 [PMID: 29625070] (Bioassay, Human) |
Bioassay |
Human |
| S Kotha, S Sun, A Adams, B Hayes, KT Phong, R Nagao, JA Reems, D Gao, B Torok-Stor, JA López, Y Zheng Microvasculature-directed thrombopoiesis in a 3D in vitro marrow microenvironment PLoS ONE, 2018-04-04;13(4):e0195082. 2018-04-04 [PMID: 29617409] (Bioassay, Human) |
Bioassay |
Human |
| J Lucifora, M Bonnin, L Aillot, F Fusil, S Maadadi, L Dimier, M Michelet, O Floriot, A Ollivier, M Rivoire, M Ait-Gougho, S Daffis, SP Fletcher, A Salvetti, FL Cosset, F Zoulim, D Durantel Direct antiviral properties of TLR ligands against HBV replication in immune-competent hepatocytes Sci Rep, 2018-03-29;8(1):5390. 2018-03-29 [PMID: 29599452] (Bioassay, Human) |
Bioassay |
Human |
| A Klaesson, K Grannas, T Ebai, J Heldin, B Koos, M Leino, D Raykova, J Oelrich, L Arngården, O Söderberg, U Landegren Improved efficiency of in situ protein analysis by proximity ligation using UnFold probes Sci Rep, 2018-03-29;8(1):5400. 2018-03-29 [PMID: 29599435] (Proximity Ligation Assay (PLA), Human) |
Proximity Ligation Assay (PLA) |
Human |
| H Pei, L He, M Shao, Z Yang, Y Ran, D Li, Y Zhou, M Tang, T Wang, Y Gong, X Chen, S Yang, M Xiang, L Chen Discovery of a highly selective JAK3 inhibitor for the treatment of rheumatoid arthritis Sci Rep, 2018-03-27;8(1):5273. 2018-03-27 [PMID: 29588471] (Bioassay, Human) |
Bioassay |
Human |
| M Jiang, Y Wang, H Zhang, Y Ji, P Zhao, R Sun, C Zhang IL-37 inhibits invasion and metastasis in non-small cell lung cancer by suppressing the IL-6/STAT3 signaling pathway Thorac Cancer, 2018-03-25;0(0):. 2018-03-25 [PMID: 29575809] (Bioassay, Human) |
Bioassay |
Human |
| C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti Anisakis pegreffii impacts differentiation and function of human dendritic cells Parasite Immunol., 2018-05-01;0(0):e12527. 2018-05-01 [PMID: 29569735] (Bioassay, Human) |
Bioassay |
Human |
| A Ohsaki, Y Miyano, R Tanaka, SI Tanuma, S Kojima, M Tsukimoto A novel mechanism of ?-irradiation-induced IL-6 production mediated by P2Y11 receptor in epidermal keratinocytes Biol. Pharm. Bull., 2018-03-16;0(0):. 2018-03-16 [PMID: 29553088] (ELISA (Standard)) |
ELISA (Standard) |
|
| H Fraser, N Safinia, N Grageda, S Thirkell, K Lowe, LJ Fry, C Scottá, A Hope, C Fisher, R Hilton, D Game, P Harden, A Bushell, K Wood, RI Lechler, G Lombardi A Rapamycin-Based GMP-Compatible Process for the Isolation and Expansion of Regulatory T Cells for Clinical Trials Mol Ther Methods Clin Dev, 2018-01-31;8(0):198-209. 2018-01-31 [PMID: 29552576] (Bioassay, Human) |
Bioassay |
Human |
| S Zheng, E Papalexi, A Butler, W Stephenson, R Satija Molecular transitions in early progenitors during human cord blood hematopoiesis Mol. Syst. Biol., 2018-03-15;14(3):e8041. 2018-03-15 [PMID: 29545397] (Bioassay, Human) |
Bioassay |
Human |
| JG Chen, X Liu, M Munshi, L Xu, N Tsakmaklis, MG Demos, A Kofides, ML Guerrera, GG Chan, CJ Patterson, KE Meid, J Gustine, T Dubeau, P Severns, JJ Castillo, ZR Hunter, J Wang, SJ Buhrlage, NS Gray, SP Treon, G Yang BTKCys481Serdrives ibrutinib resistance via ERK1/2, and protects BTKWild-TypeMYD88 mutated cells by a paracrine mechanism Blood, 2018-03-01;0(0):. 2018-03-01 [PMID: 29496671] (Bioassay, Human) |
Bioassay |
Human |
| CB Ching, S Gupta, B Li, H Cortado, N Mayne, AR Jackson, KM McHugh, B Becknell Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection Kidney Int., 2018-02-21;0(0):. 2018-02-21 [PMID: 29475562] (Bioassay, Human) |
Bioassay |
Human |
| R Wilson, M Makuch, AK Kienzler, J Varley, J Taylor, M Woodhall, J Palace, MI Leite, P Waters, SR Irani Condition-dependent generation of aquaporin-4 antibodies from circulating B cells in neuromyelitis optica Brain, 2018-04-01;141(4):1063-1074. 2018-04-01 [PMID: 29447335] (Bioassay, Human) |
Bioassay |
Human |
| A Palau, AK Garz, J Diesch, A Zwick, R Malinverni, V Valero, K Lappin, R Casquero, A Lennartsso, J Zuber, T Navarro, KI Mills, KS Götze, M Buschbeck Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes Oncotarget, 2017-12-01;8(70):115002-115017. 2017-12-01 [PMID: 29383137] (Bioassay, Human) |
Bioassay |
Human |
| F Zhang, G Liu, D Li, C Wei, J Hao DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway J. Immunol., 2018-01-29;0(0):. 2018-01-29 [PMID: 29378913] (Bioassay, Human) |
Bioassay |
Human |
| H Alsaffar, N Martino, JP Garrett, AP Adam Interleukin-6 promotes a sustained loss of endothelial barrier function via Janus kinase-mediated STAT3 phosphorylation and de novo protein synthesis Am. J. Physiol., Cell Physiol., 2018-01-10;0(0):. 2018-01-10 [PMID: 29351406] (Bioassay, Human) |
Bioassay |
Human |
| R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies Proc. Natl. Acad. Sci. U.S.A., 2018-01-16;0(0):. 2018-01-16 [PMID: 29339495] (Bioassay) |
Bioassay |
|
| Q Zhang, Z Yang, Q Han, H Bai, Y Wang, X Yi, Z Yi, L Yang, L Jiang, X Song, Y Kuang, Y Zhu G6PD promotes renal cell carcinoma proliferation through positive feedback regulation of p-STAT3 Oncotarget, 2017-11-20;8(65):109043-109060. 2017-11-20 [PMID: 29312589] (Bioassay, Human) |
Bioassay |
Human |
| K Schmitt, P Charlins, M Veselinovi, L Kinner-Bib, S Hu, J Curlin, L Remling-Mu, KE Olson, T Aboellail, R Akkina Zika viral infection and neutralizing human antibody response in a BLT humanized mouse model Virology, 2018-01-06;515(0):235-242. 2018-01-06 [PMID: 29310105] (Bioassay, Human) |
Bioassay |
Human |
| YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells PLoS ONE, 2018-01-03;13(1):e0190638. 2018-01-03 [PMID: 29298343] (Bioassay, Human) |
Bioassay |
Human |
| GE Tyzack, CE Hall, CR Sibley, T Cymes, S Forostyak, G Carlino, IF Meyer, G Schiavo, SC Zhang, GM Gibbons, J Newcombe, R Patani, A Lakatos A neuroprotective astrocyte state is induced by neuronal signal EphB1 but fails in ALS models Nat Commun, 2017-10-27;8(1):1164. 2017-10-27 [PMID: 29079839] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| S Radecke, K Schwarz, F Radecke Genome-wide Mapping of Off-Target Events in Single-Stranded Oligodeoxynucleotide-Mediated Gene Repair Experiments Mol. Ther., 2017-09-15;26(1):115-131. 2017-09-15 [PMID: 28988714] (Bioassay, Human) |
Bioassay |
Human |
| Y Wang, JB Mumm, R Herbst, R Kolbeck, Y Wang IL-22 Increases Permeability of Intestinal Epithelial Tight Junctions by Enhancing Claudin-2 Expression J. Immunol., 2017-09-22;0(0):. 2017-09-22 [PMID: 28939759] (Bioassay, Human) |
Bioassay |
Human |
| A Steinert, I Linas, B Kaya, M Ibrahim, A Schlitzer, P Hruz, K Radulovic, L Terraccian, AJ Macpherson, JH Niess The Stimulation of Macrophages with TLR Ligands Supports Increased IL-19 Expression in Inflammatory Bowel Disease Patients and in Colitis Models J. Immunol., 2017-09-01;0(0):. 2017-09-01 [PMID: 28864472] (Bioassay, Mouse) |
Bioassay |
Mouse |
| NJ Palpant, Y Wang, B Hadland, RJ Zaunbreche, M Redd, D Jones, L Pabon, R Jain, J Epstein, WL Ruzzo, Y Zheng, I Bernstein, A Margolin, CE Murry Chromatin and Transcriptional Analysis of Mesoderm Progenitor Cells Identifies HOPX as a Regulator of Primitive Hematopoiesis Cell Rep, 2017-08-15;20(7):1597-1608. 2017-08-15 [PMID: 28813672] (Bioassay, Human) |
Bioassay |
Human |
| HP Hsu, MD Lai, JC Lee, MC Yen, TY Weng, WC Chen, JH Fang, YL Chen Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling Sci Rep, 2017-07-19;7(1):5823. 2017-07-19 [PMID: 28725043] (Bioassay, Human) |
Bioassay |
Human |
| JH von Steman, AS Rigas, LW Thørner, DGK Rasmussen, OB Pedersen, K Rostgaard, C Erikstrup, H Ullum, MB Hansen Prevalence and correlation of cytokine-specific autoantibodies with epidemiological factors and C-reactive protein in 8,972 healthy individuals: Results from the Danish Blood Donor Study PLoS ONE, 2017-06-30;12(6):e0179981. 2017-06-30 [PMID: 28665954] (Control, Human) |
Control |
Human |
| J Ye, Y Wang, X Liu, L Li, A Opejin, EC Hsueh, H Luo, T Wang, D Hawiger, G Peng TLR7 Signaling Regulates Th17 Cells and Autoimmunity: Novel Potential for Autoimmune Therapy J. Immunol., 2017-06-26;0(0):. 2017-06-26 [PMID: 28652396] (Bioassay, Human) |
Bioassay |
Human |
| B Zhu, S Chen, X Hu, X Jin, Y Le, L Cao, Z Yuan, Z Lin, S Jiang, L Sun, L Yu Knockout of the Nogo-B Gene Attenuates Tumor Growth and Metastasis in Hepatocellular Carcinoma Neoplasia, 2017-06-17;19(7):583-593. 2017-06-17 [PMID: 28628795] (Bioassay, Human) |
Bioassay |
Human |
| E Forcade, K Paz, R Flynn, B Griesenaue, T Amet, W Li, L Liu, G Bakoyannis, D Jiang, HW Chu, M Lobera, J Yang, DS Wilkes, J Du, K Gartlan, GR Hill, KP MacDonald, EL Espada, P Blanco, JS Serody, J Koreth, CS Cutler, JH Antin, RJ Soiffer, J Ritz, S Paczesny, BR Blazar An activated Th17-prone T cell subset involved in chronic graft-versus-host disease sensitive to pharmacological inhibition JCI Insight, 2017-06-15;2(12):. 2017-06-15 [PMID: 28614794] (Bioassay, Human) |
Bioassay |
Human |
| A Mayati, A Moreau, C Denizot, B Stieger, Y Parmentier, O Fardel ?2-adrenergic receptor-mediated in vitro regulation of human hepatic drug transporter expression by epinephrine Eur J Pharm Sci, 2017-06-08;0(0):. 2017-06-08 [PMID: 28603032] (Bioassay, Human) |
Bioassay |
Human |
| D Wang, S Tang, Q Zhang Maslinic acid suppresses the growth of human gastric cells by inducing apoptosis via inhibition of the interleukin-6 mediated Janus kinase/signal transducer and activator of transcription 3 signaling pathway Oncol Lett, 2017-04-21;13(6):4875-4881. 2017-04-21 [PMID: 28599489] (Bioassay, Human) |
Bioassay |
Human |
| J Geng, S Yu, H Zhao, X Sun, X Li, P Wang, X Xiong, L Hong, C Xie, J Gao, Y Shi, J Peng, RL Johnson, N Xiao, L Lu, J Han, D Zhou, L Chen The transcriptional coactivator TAZ regulates reciprocal differentiation of TH17 cells and Treg cells Nat. Immunol., 2017-05-15;0(0):. 2017-05-15 [PMID: 28504697] (Bioassay, Human) |
Bioassay |
Human |
| Y Kanamori, M Murakami, M Sugiyama, O Hashimoto, T Matsui, M Funaba IL-1? transcriptionally activates hepcidin by inducing C/EBP? expression in hepatocytes J. Biol. Chem., 2017-04-24;0(0):. 2017-04-24 [PMID: 28438835] (Bioassay, Human) |
Bioassay |
Human |
| Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes Am J Transl Res, 2017-02-15;9(2):454-465. 2017-02-15 [PMID: 28337274] (Bioassay, Human) |
Bioassay |
Human |
| Y Kokubu, T Yamaguchi, K Kawabata In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells Biochem. Biophys. Res. Commun, 2017-03-21;0(0):. 2017-03-21 [PMID: 28336435] (Bioassay, Human) |
Bioassay |
Human |
| JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9 J. Immunol, 2017-03-06;0(0):. 2017-03-06 [PMID: 28264968] (Bioassay, Human) |
Bioassay |
Human |
| H He, AE Kuriyan, CW Su, M Mahabole, Y Zhang, YT Zhu, HW Flynn, JM Parel, SC Tseng Inhibition of Proliferation and Epithelial Mesenchymal Transition in Retinal Pigment Epithelial Cells by Heavy Chain-Hyaluronan/Pentraxin 3 Sci Rep, 2017-03-02;7(0):43736. 2017-03-02 [PMID: 28252047] (Bioassay, Human) |
Bioassay |
Human |
| AS Pachori, M Madan, YO Nunez Lope, F Yi, C Meyer, AA Seyhan Reduced skeletal muscle secreted frizzled-related protein 3 is associated with inflammation and insulin resistance Obesity (Silver Spring), 2017-02-27;0(0):. 2017-02-27 [PMID: 28240822] (Bioassay, Human) |
Bioassay |
Human |
| H Tsukamoto, K Fujieda, M Hirayama, T Ikeda, A Yuno, K Matsumura, D Fukuma, K Araki, H Mizuta, H Nakayama, S Senju, Y Nishimura Soluble IL-6R expressed by myeloid cells reduces tumor-specific Th1 differentation and drives tumor progression Cancer Res, 2017-02-24;0(0):. 2017-02-24 [PMID: 28235765] (Bioassay, Human) |
Bioassay |
Human |
| JS Muhammad, S Nanjo, T Ando, S Yamashita, T Maekita, T Ushijima, Y Tabuchi, T Sugiyama Autophagy Impairment by Helicobacter pylori-induced Methylation Silencing of MAP1LC3Av1 Promotes Gastric Carcinogenesis Int. J. Cancer, 2017-03-14;0(0):. 2017-03-14 [PMID: 28214334] (Bioassay, Rat) |
Bioassay |
Rat |
| M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells Clin. Cancer Res, 2017-02-09;0(0):. 2017-02-09 [PMID: 28183713] (Bioassay, Mouse) |
Bioassay |
Mouse |
| C Lin, W Liao, Y Jian, Y Peng, X Zhang, L Ye, Y Cui, B Wang, X Wu, Z Xiong, S Wu, J Li, X Wang, L Song CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling Oncogene, 2017-02-06;0(0):. 2017-02-06 [PMID: 28166202] (Bioassay, Human) |
Bioassay |
Human |
| A Bott, N Erdem, S Lerrer, A Hotz-Wagen, C Breunig, K Abnaof, A Wörner, H Wilhelm, E Münsterman, A Ben-Baruch, S Wiemann miRNA-1246 induces pro-inflammatory responses in mesenchymal stem/stromal cells by regulating PKA and PP2A Oncotarget, 2017-07-04;8(27):43897-43914. 2017-07-04 [PMID: 28159925] (Bioassay, Human) |
Bioassay |
Human |
| R Adams, RJ Burnley, CR Valenzano, O Qureshi, C Doyle, S Lumb, M Del Carmen, R Griffin, D McMillan, RD Taylor, C Meier, P Mori, LM Griffin, U Wernery, J Kinne, S Rapecki, TS Baker, AD Lawson, M Wright, A Ettorre Discovery of a junctional epitope antibody that stabilizes IL-6 and gp80 protein:protein interaction and modulates its downstream signaling Sci Rep, 2017-01-30;7(0):37716. 2017-01-30 [PMID: 28134246] (Bioassay, Human) |
Bioassay |
Human |
| KZ Oben, BW Gachuki, SS Alhakeem, MK McKenna, Y Liang, DK St Clair, VM Rangnekar, S Bondada Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1) PLoS ONE, 2017-01-12;12(1):e0169767. 2017-01-12 [PMID: 28081176] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Elias S, Schmidt A, Kannan V, Andersson J, Tegner J TGF-beta Affects the Differentiation of Human GM-CSF+ CD4+ T Cells in an Activation- and Sodium-Dependent Manner. Front Immunol, 2016-12-23;7(0):603. 2016-12-23 [PMID: 28066414] (Bioassay, Human) |
Bioassay |
Human |
| L J Spicer G protein-coupled receptor 34 in ovarian granulosa cells of cattle: changes during follicular development and potential functional implications Domest. Anim. Endocrinol, 2016-12-11;59(0):90-99. 2016-12-11 [PMID: 28040605] (Bioassay, Bovine) |
Bioassay |
Bovine |
| Anja Kerstein Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis J. Autoimmun, 2016-12-28;0(0):. 2016-12-28 [PMID: 28040323] (Bioassay, Human) |
Bioassay |
Human |
| Senescent peritoneal mesothelium creates a niche for ovarian cancer metastases Cell Death Dis, 2016-12-29;7(12):e2565. 2016-12-29 [PMID: 28032864] (Bioassay, Human) |
Bioassay |
Human |
| Yukio Takeshita Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro Neurol Neuroimmunol Neuroinflamm, 2016-12-19;4(1):e311. 2016-12-19 [PMID: 28018943] (Bioassay, Human) |
Bioassay |
Human |
| Aurélie Chiche Injury-Induced Senescence Enables In�Vivo Reprogramming in Skeletal Muscle Cell Stem Cell, 2016-12-22;0(0):. 2016-12-22 [PMID: 28017795] (Bioassay, Human) |
Bioassay |
Human |
| Structure-based virtual screening and characterization of a novel IL-6 antagonistic compound from synthetic compound database Drug Des Devel Ther, 2016-12-15;10(0):4091-4100. 2016-12-15 [PMID: 28008232] (Bioassay, Human) |
Bioassay |
Human |
| Ras oncogene-independent activation of RALB signaling is a targetable mechanism of escape from NRAS(V12) oncogene addiction in acute myeloid leukemia Oncogene, 2016-12-19;0(0):. 2016-12-19 [PMID: 27991934] (Bioassay, Human) |
Bioassay |
Human |
| Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling Sci Rep, 2016-12-19;6(0):39190. 2016-12-19 [PMID: 27991524] (Bioassay, Human) |
Bioassay |
Human |
| Rajeev K Tyagi A generic RNA pulsed DC based approach for developing therapeutic intervention against Nasopharyngeal Carcinoma Hum Vaccin Immunother, 2016-11-30;0(0):0. 2016-11-30 [PMID: 27901642] (Bioassay, Human) |
Bioassay |
Human |
| Andrea Todisco Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2. 2016-11-17 [PMID: 27856416] (Bioassay, Human) |
Bioassay |
Human |
| Robert Sabat MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations Mediators Inflamm., 2016-10-23;2016(0):4097574. 2016-10-23 [PMID: 27843200] (Bioassay, Human) |
Bioassay |
Human |
| Derek N J Hart The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population J. Immunol., 2016-11-11;0(0):. 2016-11-11 [PMID: 27837105] (Bioassay, Human) |
Bioassay |
Human |
| Angela P Bastidas-C, Astrid D Bakker, Behrouz Zandieh-D, Cornelis J Kleverlaa, Nathalie Bravenboe, Tim Forouzanf, Jenneke Klein-Nul Cytokines TNF-?, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells. Stem Cells International, 2016-09-07;0(0):1687-966X. 2016-09-07 [PMID: 27667999] (Bioassay, Human) |
Bioassay |
Human |
| Activated monocytes resist elimination by retinal pigment epithelium and downregulate their OTX2 expression via TNF-? Aging Cell, 2016-09-22;0(0):. 2016-09-22 [PMID: 27660103] (Bioassay, Porcine) |
Bioassay |
Porcine |
| Involvement of Spinal IL-6 Trans-Signaling in the Induction of Hyperexcitability of Deep Dorsal Horn Neurons by Spinal Tumor Necrosis Factor-Alpha J Neurosci, 2016-09-21;36(38):9782-91. 2016-09-21 [PMID: 27656018] (Bioassay, Rat) |
Bioassay |
Rat |
| Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation J Biol Chem, 2016-09-20;0(0):. 2016-09-20 [PMID: 27650497] (Bioassay, Human) |
Bioassay |
Human |
| Signaling and Immunoresolving Actions of Resolvin D1 in Inflamed Human Visceral Adipose Tissue J Immunol, 2016-09-19;0(0):. 2016-09-19 [PMID: 27647830] (Bioassay, Human) |
Bioassay |
Human |
| Regulation of Polycystin-1 Function by Calmodulin Binding PLoS ONE, 2016-08-25;11(8):e0161525. 2016-08-25 [PMID: 27560828] (Bioassay, Human) |
Bioassay |
Human |
| Jak1-STAT3 signals are essential effectors of the USP6/TRE17 oncogene in tumorigenesis Cancer Res, 2016-07-20;0(0):. 2016-07-20 [PMID: 27440725] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Olaf Pinkenburg The Human Antimicrobial Protein Bactericidal/Permeability-Increasing Protein (BPI) Inhibits the Infectivity of Influenza A Virus PLoS ONE, 2016-06-06;11(6):e0156929. 2016-06-06 [PMID: 27273104] (ELISA (Standard), Human) |
ELISA (Standard) |
Human |
| Marcin Ratajewski Expression of human gene coding ROR?T receptor depends on the Sp2 transcription factor J Leukoc Biol, 2016-06-02;0(0):. 2016-06-02 [PMID: 27256574] (Bioassay, Human) |
Bioassay |
Human |
| MM Halpert, V Konduri, D Liang, Y Chen, JB Wing, S Paust, JM Levitt, WK Decker Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7 Stem Cells Dev., 2016-05-02;25(10):774-87. 2016-05-02 [PMID: 26979751] (Bioassay, Human) |
Bioassay |
Human |
| Zhong H, Davis A, Ouzounova M, Carrasco R, Chen C, Breen S, Chang Y, Huang J, Liu Z, Yao Y, Hurt E, Moisan J, Fung M, Tice D, Clouthier S, Xiao Z, Wicha M, Korkaya H, Hollingsworth R A Novel IL6 Antibody Sensitizes Multiple Tumor Types to Chemotherapy Including Trastuzumab-Resistant Tumors. Cancer Res, 2016-01-07;76(2):480-90. 2016-01-07 [PMID: 26744529] (Bioassay, Human) |
Bioassay |
Human |
| Huston S, Ngamskulrungroj P, Xiang R, Ogbomo H, Stack D, Li S, Timm-McCann M, Kyei S, Oykhman P, Kwon-Chung K, Mody C Cryptococcus gattii Capsule Blocks Surface Recognition Required for Dendritic Cell Maturation Independent of Internalization and Antigen Processing. J Immunol, 2016-01-06;196(3):1259-71. 2016-01-06 [PMID: 26740109] (Bioassay, Human) |
Bioassay |
Human |
| BR Yoon, YH Chung, SJ Yoo, K Kawara, J Kim, IS Yoo, CG Park, SW Kang, WW Lee Preferential Induction of the T Cell Auxiliary Signaling Molecule B7-H3 on Synovial Monocytes in Rheumatoid Arthritis J. Biol. Chem, 2015-12-23;291(8):4048-57. 2015-12-23 [PMID: 26702052] (Bioassay, Human) |
Bioassay |
Human |
| Min H, Kim S, Baek S, Woo J, Park J, Cho M, Lee J, Kwok S, Kim S, Park S Anthocyanin Extracted from Black Soybean Seed Coats Prevents Autoimmune Arthritis by Suppressing the Development of Th17 Cells and Synthesis of Proinflammatory Cytokines by Such Cells, via Inhibition of NF-kappaB. PLoS ONE, 2015-11-06;10(11):e0138201. 2015-11-06 [PMID: 26544846] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Dong B, Shi Z, Wang J, Wu J, Yang Z, Fang K IL-6 Inhibits the Targeted Modulation of PDCD4 by miR-21 in Prostate Cancer. PLoS ONE, 2015-08-07;10(8):e0134366. 2015-08-07 [PMID: 26252635] (Bioassay, Human) |
Bioassay |
Human |
| Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma. J Transl Med, 2015-06-20;13(0):197. 2015-06-20 [PMID: 26088750] (Bioassay, Human) |
Bioassay |
Human |
| Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala-Dilke K, Leinster D, Zhong H, Hollingsworth R, Thompson R, Whiteford J, Balkwill F Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res, 2015-06-16;75(15):3098-107. 2015-06-16 [PMID: 26081809] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, Stope M, Martincuks A, Vogt M, Gortz D, Camporeale A, Poli V, Muller-Newen G, Brummendorf T, Ziegler P Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy. J Hematol Oncol, 2015-06-09;8(0):64. 2015-06-09 [PMID: 26054961] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Hong S, Choi J, Lee S, Park Y, Park K, Lee J, Kim J, Gajulapati V, Goo J, Singh S, Lee K, Kim Y, Im S, Ahn S, Rose-John S, Heo T, Choi Y A Novel Small-Molecule Inhibitor Targeting the IL-6 Receptor beta Subunit, Glycoprotein 130. J Immunol, 2015-05-29;195(1):237-45. 2015-05-29 [PMID: 26026064] (Bioassay, Human) |
Bioassay |
Human |
| Ling Y, Cypowyj S, Aytekin C, Galicchio M, Camcioglu Y, Nepesov S, Ikinciogullari A, Dogu F, Belkadi A, Levy R, Migaud M, Boisson B, Bolze A, Itan Y, Goudin N, Cottineau J, Picard C, Abel L, Bustamante J, Casanova J, Puel A Inherited IL-17RC deficiency in patients with chronic mucocutaneous candidiasis. J Exp Med, 2015-04-27;212(5):619-31. 2015-04-27 [PMID: 25918342] (Bioassay, Human) |
Bioassay |
Human |
| Kim J, Tillu D, Quinn T, Mejia G, Shy A, Asiedu M, Murad E, Schumann A, Totsch S, Sorge R, Mantyh P, Dussor G, Price T Spinal dopaminergic projections control the transition to pathological pain plasticity via a D1/D5-mediated mechanism. J Neurosci, 2015-04-22;35(16):6307-17. 2015-04-22 [PMID: 25904784] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Ilkow C, Marguerie M, Batenchuk C, Mayer J, Ben Neriah D, Cousineau S, Falls T, Jennings V, Boileau M, Bellamy D, Bastin D, de Souza C, Alkayyal A, Zhang J, Le Boeuf F, Arulanandam R, Stubbert L, Sampath P, Thorne S, Paramanthan P, Chatterjee A, Strieter R, Burdick M, Addison C, Stojdl D, Atkins H, Auer R, Diallo J, Lichty B, Bell J Reciprocal cellular cross-talk within the tumor microenvironment promotes oncolytic virus activity. Nat Med, 2015-04-20;21(5):530-6. 2015-04-20 [PMID: 25894825] (Bioassay, Human) |
Bioassay |
Human |
| Simamura E, Arikawa T, Ikeda T, Shimada H, Shoji H, Masuta H, Nakajima Y, Otani H, Yonekura H, Hatta T Melanocortins contribute to sequential differentiation and enucleation of human erythroblasts via melanocortin receptors 1, 2 and 5. PLoS ONE, 2015-04-10;10(4):e0123232. 2015-04-10 [PMID: 25860801] (Bioassay, Human) |
Bioassay |
Human |
| Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M. Respir Res, 2015-02-07;16(0):14. 2015-02-07 [PMID: 25849622] (Bioassay, Human) |
Bioassay |
Human |
| Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, Seftel M, Lipton J, Gupta V, Humar A, Husain S Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis. PLoS ONE, 2015-04-02;10(4):e0123171. 2015-04-02 [PMID: 25835547] (Bioassay, Human) |
Bioassay |
Human |
| Patterson , Scott D, Rossi , John M, Paweletz , Katherin, Fitzpatrick , V Dan, Begley , C Glenn, Busse , Leigh, Elliott , Steve, McCaffery , Ian Functional EpoR pathway utilization is not detected in primary tumor cells isolated from human breast, non-small cell lung, colorectal, and ovarian tumor tissues. PLoS ONE, 2015-03-25;10(3):e0122149. 2015-03-25 [PMID: 25807104] (Bioassay, Human) |
Bioassay |
Human |
| Irvin S, Herold B Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk. PLoS ONE, 2015-03-23;10(3):e0121135. 2015-03-23 [PMID: 25798593] (Bioassay, Human) |
Bioassay |
Human |
| Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, Usami I, Sakamoto S, Abe H, Watanabe T, Yamori T, Shibasaki M, Nomoto A Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFalpha-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE, 2015-03-18;10(3):e0119415. 2015-03-18 [PMID: 25785838] (Bioassay, Human) |
Bioassay |
Human |
| Gentilini M, Velasquez L, Barrionuevo P, Arriola Benitez P, Giambartolomei G, Delpino M Adrenal steroids modulate the immune response during Brucella abortus infection by a mechanism that depends on the regulation of cytokine production. Infect Immun, 2015-03-02;83(5):1973-82. 2015-03-02 [PMID: 25733519] (Bioassay, Human) |
Bioassay |
Human |
| James B Canavan Developing in vitro expanded CD45RA+ regulatory T cells as an adoptive cell therapy for Crohn's disease Gut, 2015-02-24;65(4):584-94. 2015-02-24 [PMID: 25715355] (Bioassay, Human) |
Bioassay |
Human |
| Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, Hauser K, Yao Z, Boyce B, Kordula T RelB/p50 complexes regulate cytokine-induced YKL-40 expression. J Immunol, 2015-02-13;194(6):2862-70. 2015-02-13 [PMID: 25681350] (Bioassay, Human) |
Bioassay |
Human |
| Lee J, Graham M, Collins T, Lee J, Hong S, McNicol A, Shapovalova Z, Bhatia M Reversible lineage-specific priming of human embryonic stem cells can be exploited to optimize the yield of differentiated cells. Stem Cells, 2015-04-01;33(4):1142-52. 2015-04-01 [PMID: 25639500] (Bioassay, Human) |
Bioassay |
Human |
| Herova M, Schmid M, Gemperle C, Hersberger M ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages. J Immunol, 2015-01-30;194(5):2330-7. 2015-01-30 [PMID: 25637017] (Bioassay, Human) |
Bioassay |
Human |
| Fichtner S, Hose D, Engelhardt M, Meissner T, Neuber B, Krasniqi F, Raab M, Schonland S, Ho A, Goldschmidt H, Hundemer M Association of antigen-specific T-cell responses with antigen expression and immunoparalysis in multiple myeloma. Clin Cancer Res, 2015-01-21;21(7):1712-21. 2015-01-21 [PMID: 25609061] (Bioassay, Human) |
Bioassay |
Human |
| Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells. Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62. 2015-01-20 [PMID: 25604685] (Bioassay, Human) |
Bioassay |
Human |
| Goedken E, Argiriadi M, Banach D, Fiamengo B, Foley S, Frank K, George J, Harris C, Hobson A, Ihle D, Marcotte D, Merta P, Michalak M, Murdock S, Tomlinson M, Voss J Tricyclic covalent inhibitors selectively target Jak3 through an active site thiol. J Biol Chem, 2014-12-31;290(8):4573-89. 2014-12-31 [PMID: 25552479] (Bioassay, Human) |
Bioassay |
Human |
| Venkatesha V, Joshi A, Venkataraman M, Sonawane V, Bhatia D, Tannu P, Bose J, Choudhari S, Srivastava A, Pandey P, Lad V, Sangana R, Ahmed T, Damre A, Deore V, Sahu B, Kumar S, Sharma S, Agarwal V P7170, a novel inhibitor of mTORC1/mTORC2 and Activin receptor-like Kinase 1 (ALK1) inhibits the growth of non small cell lung cancer. Mol Cancer, 2014-12-02;13(0):259. 2014-12-02 [PMID: 25466244] (Bioassay, Human) |
Bioassay |
Human |
| Lee D, Sung K, Bartlett D, Kwon Y, Lee Y HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells. Cell Signal, 2014-11-18;27(2):293-305. 2014-11-18 [PMID: 25446253] (Bioassay, Human) |
Bioassay |
Human |
| Sobotta M, Liou W, Stocker S, Talwar D, Oehler M, Ruppert T, Scharf A, Dick T Peroxiredoxin-2 and STAT3 form a redox relay for H2O2 signaling. Nat Chem Biol, 2014-11-24;11(1):64-70. 2014-11-24 [PMID: 25402766] (Bioassay, Human) |
Bioassay |
Human |
| Lam , Sharon, Sung , Julia, Cruz , Conrad, Castillo-Caro , Paul, Ngo , Minhtran, Garrido , Carolina, Kuruc , Joann, Archin , Nancie, Rooney , Cliona, Margolis , David, Bollard , Catherin Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy. Mol Ther, 2014-11-04;23(2):387-95. 2014-11-04 [PMID: 25366030] (Bioassay, Human) |
Bioassay |
Human |
| Chinen Y, Kuroda J, Shimura Y, Nagoshi H, Kiyota M, Yamamoto-Sugitani M, Mizutani S, Sakamoto N, Ri M, Kawata E, Kobayashi T, Matsumoto Y, Horiike S, Iida S, Taniwaki M Phosphoinositide protein kinase PDPK1 is a crucial cell signaling mediator in multiple myeloma. Cancer Res, 2014-09-30;74(24):7418-29. 2014-09-30 [PMID: 25269480] (Bioassay, Human) |
Bioassay |
Human |
| Davaine J, Quillard T, Brion R, Laperine O, Guyomarch B, Merlini T, Chatelais M, Guilbaud F, Brennan M, Charrier C, Heymann D, Goueffic Y, Heymann M Osteoprotegerin, pericytes and bone-like vascular calcification are associated with carotid plaque stability. PLoS ONE, 2014-09-26;9(9):e107642. 2014-09-26 [PMID: 25259713] (Bioassay, Human) |
Bioassay |
Human |
| Kuang D, Xiao X, Zhao Q, Chen M, Li X, Liu R, Wei Y, Ouyang F, Chen D, Wu Y, Lao X, Deng H, Zheng L B7-H1-expressing antigen-presenting cells mediate polarization of protumorigenic Th22 subsets. J Clin Invest, 2014-09-17;124(10):4657-67. 2014-09-17 [PMID: 25244097] (Bioassay, Human) |
Bioassay |
Human |
| Zhu H, Han C, Lu D, Wu T miR-17-92 cluster promotes cholangiocarcinoma growth: evidence for PTEN as downstream target and IL-6/Stat3 as upstream activator. Am J Pathol, 2014-10-01;184(10):2828-39. 2014-10-01 [PMID: 25239565] (Bioassay, Human) |
Bioassay |
Human |
| Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion. PLoS ONE, 2014-09-03;9(9):e106673. 2014-09-03 [PMID: 25184791] (Bioassay, Human) |
Bioassay |
Human |
| Kwon , Sang-Mo, Lee , Jun-Hee, Lee , Sang-Hun, Jung , Seok-Yun, Kim , Da-Yeon, Kang , Song-Hwa, Yoo , So-Young, Hong , Jong-Kyu, Park , Ji-Hye, Kim , Jung-Hee, Kim , Sung-Woo, Kim , Yeon-Ju, Lee , Sun-Jin, Kim , Hwi-Gon, Asahara , Takayuki Cross talk with hematopoietic cells regulates the endothelial progenitor cell differentiation of CD34 positive cells. PLoS ONE, 2014-08-28;9(8):e106310. 2014-08-28 [PMID: 25166961] (Bioassay, Human) |
Bioassay |
Human |
| Dighe N, Khoury M, Mattar C, Chong M, Choolani M, Chen J, Antoniou M, Chan J Long-term reproducible expression in human fetal liver hematopoietic stem cells with a UCOE-based lentiviral vector. PLoS ONE, 2014-08-12;9(8):e104805. 2014-08-12 [PMID: 25118036] (Bioassay, Human) |
Bioassay |
Human |
| Anderson J, Titz B, Akiyama R, Komisopoulou E, Park A, Tap W, Graeber T, Denny C Phosphoproteomic profiling reveals IL6-mediated paracrine signaling within the Ewing sarcoma family of tumors. Mol Cancer Res, 2014-08-04;12(12):1740-54. 2014-08-04 [PMID: 25092916] (Bioassay, Human) |
Bioassay |
Human |
| Bam R, Venkateshaiah S, Khan S, Ling W, Randal S, Li X, Zhang Q, van Rhee F, Barlogie B, Epstein J, Yaccoby S Role of Bruton's tyrosine kinase (BTK) in growth and metastasis of INA6 myeloma cells. Blood Cancer J, 2014-08-01;4(0):e234. 2014-08-01 [PMID: 25083818] (Bioassay, Human) |
Bioassay |
Human |
| Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk. J Immunol, 2014-07-30;193(5):2297-305. 2014-07-30 [PMID: 25080481] (Bioassay, Human) |
Bioassay |
Human |
| Han L, Yang J, Wang X, Wu Q, Yin S, Li Z, Zhang J, Xing Y, Chen Z, Tsun A, Li D, Piccioni M, Zhang Y, Guo Q, Jiang L, Bao L, Lv L, Li B The E3 deubiquitinase USP17 is a positive regulator of retinoic acid-related orphan nuclear receptor gammat (RORgammat) in Th17 cells. J Biol Chem, 2014-07-28;289(37):25546-55. 2014-07-28 [PMID: 25070893] (Bioassay, Human) |
Bioassay |
Human |
| Zhang Q, Yang Z, Jia Z, Liu C, Guo C, Lu H, Chen P, Ma K, Wang W, Zhou C ISL-1 is overexpressed in non-Hodgkin lymphoma and promotes lymphoma cell proliferation by forming a p-STAT3/p-c-Jun/ISL-1 complex. Mol Cancer, 2014-07-29;13(0):181. 2014-07-29 [PMID: 25070240] (Bioassay, Human) |
Bioassay |
Human |
| O'Toole A, Michielsen A, Nolan B, Tosetto M, Sheahan K, Mulcahy H, Winter D, Hyland J, O'Connell P, Fennelly D, O'Donoghue D, O'Sullivan J, Doherty G, Ryan E Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive. Br J Cancer, 2014-07-24;111(5):927-32. 2014-07-24 [PMID: 25058349] (Bioassay, Human) |
Bioassay |
Human |
| Weinkopff T, Mackenzie C, Eversole R, Lammie P Filarial excretory-secretory products induce human monocytes to produce lymphangiogenic mediators. PLoS Negl Trop Dis, 2014-07-10;8(7):e2893. 2014-07-10 [PMID: 25010672] (Bioassay, Human) |
Bioassay |
Human |
| Melemedjian O, Tillu D, Moy J, Asiedu M, Mandell E, Ghosh S, Dussor G, Price T Local translation and retrograde axonal transport of CREB regulates IL-6-induced nociceptive plasticity. Mol Pain, 2014-07-04;10(0):45. 2014-07-04 [PMID: 24993495] (Bioassay, In Vivo, Mouse) |
Bioassay, In Vivo |
Mouse |
| Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz M Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis. Blood, 2014-07-02;124(9):1393-403. 2014-07-02 [PMID: 24990886] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Kastrati I, Canestrari E, Frasor J PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres. Oncogene, 2014-06-23;34(18):2309-16. 2014-06-23 [PMID: 24954507] (Bioassay, Human) |
Bioassay |
Human |
| Tanaka , Akinobu, Zhu , Qinchang, Tan , Hui, Horiba , Hiroki, Ohnuki , Koichiro, Mori , Yasuhiro, Yamauchi , Ryoko, Ishikawa , Hiroya, Iwamoto , Akira, Kawahara , Hiroharu, Shimizu , Kuniyosh Biological activities and phytochemical profiles of extracts from different parts of bamboo (Phyllostachys pubescens). Molecules, 2014-06-18;19(6):8238-60. 2014-06-18 [PMID: 24945578] (Bioassay, Human) |
Bioassay |
Human |
| Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer M, Zhang H, Hogquist K, Evavold B, Vignali D TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential. J Immunol, 2014-06-18;193(2):571-9. 2014-06-18 [PMID: 24943217] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition. Cancer Res, 2014-06-16;74(16):4458-69. 2014-06-16 [PMID: 24934808] (Bioassay, Human) |
Bioassay |
Human |
| Linher-Melville , Katja, Singh , Gurmit The transcriptional responsiveness of LKB1 to STAT-mediated signaling is differentially modulated by prolactin in human breast cancer cells. BMC Cancer, 2014-06-09;14(0):415. 2014-06-09 [PMID: 24913037] (Bioassay, Human) |
Bioassay |
Human |
| Horwitz , Mitchell, Chao , Nelson J, Rizzieri , David A, Long , Gwynn D, Sullivan , Keith M, Gasparetto , Cristina, Chute , John P, Morris , Ashley, McDonald , Carolyn, Waters-Pick , Barbara, Stiff , Patrick, Wease , Steven, Peled , Amnon, Snyder , David, Cohen , Einat Ga, Shoham , Hadas, Landau , Efrat, Friend , Etty, Peleg , Iddo, Aschengrau , Dorit, Yackoubov , Dima, Kurtzberg , Joanne, Peled , Tony Umbilical cord blood expansion with nicotinamide provides long-term multilineage engraftment. J Clin Invest, 2014-06-09;124(7):3121-8. 2014-06-09 [PMID: 24911148] (Bioassay, Human) |
Bioassay |
Human |
| Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis. J Allergy Clin Immunol, 2014-06-06;134(2):373-81. 2014-06-06 [PMID: 24910175] (Bioassay, Human) |
Bioassay |
Human |
| Zhao Y, Xiao X, Frank S, Lin H, Xia Y Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta. Am J Physiol Endocrinol Metab, 2014-06-03;307(2):E186-98. 2014-06-03 [PMID: 24895283] (Bioassay, Human) |
Bioassay |
Human |
| Kofler D, Marson A, Dominguez-Villar M, Xiao S, Kuchroo V, Hafler D Decreased RORC-dependent silencing of prostaglandin receptor EP2 induces autoimmune Th17 cells. J Clin Invest, 2014-05-08;124(6):2513-22. 2014-05-08 [PMID: 24812667] (Bioassay, Human) |
Bioassay |
Human |
| Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, Woetmann A, Odum N, Bonefeld C, Geisler C Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE, 2014-05-02;9(5):e96695. 2014-05-02 [PMID: 24792400] (Bioassay, Human) |
Bioassay |
Human |
| Bu Y, Su F, Wang X, Gao H, Lei L, Chang N, Wu Q, Hu K, Zhu X, Chang Z, Meng K, Xiong J Protein tyrosine phosphatase PTPN9 regulates erythroid cell development through STAT3 dephosphorylation in zebrafish. J Cell Sci, 2014-04-11;127(0):2761-70. 2014-04-11 [PMID: 24727614] (Bioassay, Human) |
Bioassay |
Human |
| Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit M, Blanchet X, von Hundelshausen P, Weber C, Forssmann W, Henschler R Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells. Stem Cells Dev, 2014-05-27;23(16):1959-74. 2014-05-27 [PMID: 24708339] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Zheng Y, Chow S, Boernert K, Basel D, Mikuscheva A, Kim S, Fong-Yee C, Trivedi T, Buttgereit F, Sutherland R, Dunstan C, Zhou H, Seibel M Direct crosstalk between cancer and osteoblast lineage cells fuels metastatic growth in bone via auto-amplification of IL-6 and RANKL signaling pathways. J Bone Miner Res, 2014-09-01;29(9):1938-49. 2014-09-01 [PMID: 24676805] (Bioassay, Human) |
Bioassay |
Human |
| Shaw S, Bourne T, Meier C, Carrington B, Gelinas R, Henry A, Popplewell A, Adams R, Baker T, Rapecki S, Marshall D, Moore A, Neale H, Lawson A Discovery and characterization of olokizumab: a humanized antibody targeting interleukin-6 and neutralizing gp130-signaling. MAbs, 2014-04-02;6(3):774-82. 2014-04-02 [PMID: 24670876] (Bioassay, Human) |
Bioassay |
Human |
| Al-Sadi R, Ye D, Boivin M, Guo S, Hashimi M, Ereifej L, Ma T Interleukin-6 modulation of intestinal epithelial tight junction permeability is mediated by JNK pathway activation of claudin-2 gene. PLoS ONE, 2014-03-24;9(3):e85345. 2014-03-24 [PMID: 24662742] (Bioassay, Human) |
Bioassay |
Human |
| Umashankar , Mahadeva, Rak , Michael, Bughio , Farah, Zagallo , Patricia, Caviness , Katie, Goodrum , Felicia Antagonistic determinants controlling replicative and latent states of human cytomegalovirus infection. J Virol, 2014-03-12;88(11):5987-6002. 2014-03-12 [PMID: 24623432] (Bioassay, Human) |
Bioassay |
Human |
| Pei X, Dai Y, Felthousen J, Chen S, Takabatake Y, Zhou L, Youssefian L, Sanderson M, Bodie W, Kramer L, Orlowski R, Grant S Circumvention of Mcl-1-dependent drug resistance by simultaneous Chk1 and MEK1/2 inhibition in human multiple myeloma cells. PLoS ONE, 2014-03-04;9(3):e89064. 2014-03-04 [PMID: 24594907] (Bioassay, Human) |
Bioassay |
Human |
| Di Martino M, Gulla A, Gallo Cantafio M, Altomare E, Amodio N, Leone E, Morelli E, Lio S, Caracciolo D, Rossi M, Frandsen N, Tagliaferri P, Tassone P In vitro and in vivo activity of a novel locked nucleic acid (LNA)-inhibitor-miR-221 against multiple myeloma cells. PLoS ONE, 2014-02-21;9(2):e89659. 2014-02-21 [PMID: 24586944] (Bioassay, Human) |
Bioassay |
Human |
| Liu R, Zeng Y, Lei Z, Wang L, Yang H, Liu Z, Zhao J, Zhang H JAK/STAT3 signaling is required for TGF-beta-induced epithelial-mesenchymal transition in lung cancer cells. Int J Oncol, 2014-02-21;44(5):1643-51. 2014-02-21 [PMID: 24573038] (Bioassay, Human) |
Bioassay |
Human |
| O'Reilly S, Ciechomska M, Cant R, van Laar J Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-beta (TGF-beta) signaling promoting SMAD3 activation and fibrosis via Gremlin protein. J Biol Chem, 2014-02-18;289(14):9952-60. 2014-02-18 [PMID: 24550394] (Bioassay, Human) |
Bioassay |
Human |
| Prigent L, Robineau M, Jouneau S, Morzadec C, Louarn L, Vernhet L, Fardel O, Sparfel L The aryl hydrocarbon receptor is functionally upregulated early in the course ofvhuman T-cell activation. Eur J Immunol, 2014-02-18;44(5):1330-40. 2014-02-18 [PMID: 24549985] (Bioassay, Human) |
Bioassay |
Human |
| Valle Oseguera , Cendy A, Spencer , Juliet V cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells. PLoS ONE, 2014-02-10;9(2):e88708. 2014-02-10 [PMID: 24520416] (Bioassay, Human) |
Bioassay |
Human |
| Milwid , Jack M, Elman , Jessica, Li , Matthew, Shen , Keyue, Manrai , Arjun, Gabow , Aaron, Yarmush , Joshua, Jiao , Yunxin, Fletcher , Anne, Lee , Jungwoo, Cima , Michael, Yarmush , Martin L, Parekkadan , Biju Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators. Mol Ther, 2014-02-05;22(5):999-1007. 2014-02-05 [PMID: 24496384] (Bioassay, Human) |
Bioassay |
Human |
| Jensen B, Frandsen P, Raaby E, Schiotz P, Skov P, Poulsen L Molecular and stimulus-response profiles illustrate heterogeneity between peripheral and cord blood-derived human mast cells. J Leukoc Biol, 2014-02-03;95(6):893-901. 2014-02-03 [PMID: 24493825] (Bioassay, Human) |
Bioassay |
Human |
| McCutcheon , Krista M, Gray , Julia, Chen , Natalie, Liu , Keyi, Park , Minha, Ellsworth , Stote, Tripp , Ralph A, Tompkins , S Mark, Johnson , Scott K, Samet , Shelly, Pereira , Lenore, Kauvar , Lawrence Multiplexed screening of natural humoral immunity identifies antibodies at fine specificity for complex and dynamic viral targets. MAbs, 2014-01-08;6(2):460-73. 2014-01-08 [PMID: 24492306] (Bioassay, Human) |
Bioassay |
Human |
| Zhang M, Qian J, Lan Y, Lu Y, Li H, Hong B, Zheng Y, He J, Yang J, Yi Q Anti-beta(2)M monoclonal antibodies kill myeloma cells via cell- and complement-mediated cytotoxicity. Int J Cancer, 2014-02-07;135(5):1132-41. 2014-02-07 [PMID: 24474467] (Bioassay, Human) |
Bioassay |
Human |
| Imai F, Kishi H, Nakao K, Nishimura T, Minegishi T IL-6 up-regulates the expression of rat LH receptors during granulosa cell differentiation. Endocrinology, 2014-01-27;155(4):1436-44. 2014-01-27 [PMID: 24467743] (Bioassay, Rat) |
Bioassay |
Rat |
| Rodin S, Antonsson L, Niaudet C, Simonson O, Salmela E, Hansson E, Domogatskaya A, Xiao Z, Damdimopoulou P, Sheikhi M, Inzunza J, Nilsson A, Baker D, Kuiper R, Sun Y, Blennow E, Nordenskjold M, Grinnemo K, Kere J, Betsholtz C, Hovatta O, Tryggvason K Clonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment. Nat Commun, 2014-01-01;5(0):3195. 2014-01-01 [PMID: 24463987] (Bioassay, Human) |
Bioassay |
Human |
| Kamat V, Paluru P, Myint M, French D, Gadue P, Diamond S MicroRNA screen of human embryonic stem cell differentiation reveals miR-105 as an enhancer of megakaryopoiesis from adult CD34+ cells. Stem Cells, 2014-05-01;32(5):1337-46. 2014-05-01 [PMID: 24446170] (Bioassay, Human) |
Bioassay |
Human |
| Gupta , Shashi, Hirota , Masao, Waugh , Sheela M, Murakami , Ikuo, Suzuki , Tomoki, Muraguchi , Masahiro, Shibamori , Masafumi, Ishikawa , Yuichi, Jarvis , Thale C, Carter , Jeffrey, Zhang , Chi, Gawande , Bharat, Vrkljan , Michael, Janjic , Nebojsa, Schneider , Daniel J Chemically modified DNA aptamers bind interleukin-6 with high affinity and inhibit signaling by blocking its interaction with interleukin-6 receptor. J Biol Chem, 2014-01-12;289(12):8706-19. 2014-01-12 [PMID: 24415766] (Bioassay, Human) |
Bioassay |
Human |
| Suzuki , Hitoshi, Raska , Milan, Yamada , Koshi, Moldoveanu , Zina, Julian , Bruce A, Wyatt , Robert J, Tomino , Yasuhiko, Gharavi , Ali G, Novak , Jan Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes. J Biol Chem, 2014-01-07;289(8):5330-9. 2014-01-07 [PMID: 24398680] (Bioassay, Human) |
Bioassay |
Human |
| Mleczko-Sanecka K, Roche F, Da Silva A, Call D, D'Alessio F, Ragab A, Lapinski P, Ummanni R, Korf U, Oakes C, Damm G, D'Alessandro L, Klingmuller U, King P, Boutros M, Hentze M, Muckenthaler M Unbiased RNAi screen for hepcidin regulators links hepcidin suppression to proliferative Ras/RAF and nutrient-dependent mTOR signaling. Blood, 2014-01-02;123(10):1574-85. 2014-01-02 [PMID: 24385536] (Bioassay, Human) |
Bioassay |
Human |
| Meynard , Delphine, Sun , Chia Chi, Wu , Qifang, Chen , Wenjie, Chen , Shanzhuo, Nelson , Caroline, Waters , Michael, Babitt , Jodie L, Lin , Herbert Inflammation regulates TMPRSS6 expression via STAT5. PLoS ONE, 2013-12-23;8(12):e82127. 2013-12-23 [PMID: 24376517] (Bioassay, Human) |
Bioassay |
Human |
| Thanunchai , Maytawan, Kanrai , Pumaree, Wiboon-Ut , Suwimon, Puthavathana , Pilaipan, Hongeng , Suradej, Thitithanyanont , Arunee Tropism of avian influenza A (H5N1) virus to mesenchymal stem cells and CD34+ hematopoietic stem cells. PLoS ONE, 2013-12-10;8(12):e81805. 2013-12-10 [PMID: 24339969] (Bioassay, Human) |
Bioassay |
Human |
| Wong , Kwan Yeu, Wan , Thomas S, So , Chi Chiu, Chim , Chor San Establishment of a bortezomib-resistant Chinese human multiple myeloma cell line: MMLAL. Cancer Cell Int, 2013-12-12;13(1):122. 2013-12-12 [PMID: 24330858] (Cell Culture, Human) |
Cell Culture |
Human |
| Tolar J, McGrath J, Xia L, Riddle M, Lees C, Eide C, Keene D, Liu L, Osborn M, Lund T, Blazar B, Wagner J Patient-specific naturally gene-reverted induced pluripotent stem cells in recessive dystrophic epidermolysis bullosa. J Invest Dermatol, 2013-12-06;134(5):1246-54. 2013-12-06 [PMID: 24317394] (Bioassay, Human) |
Bioassay |
Human |
| Sjeklocha L, Wong P, Belcher J, Vercellotti G, Steer C beta-Globin sleeping beauty transposon reduces red blood cell sickling in a patient-derived CD34(+)-based in vitro model. PLoS ONE, 2013-11-18;8(11):e80403. 2013-11-18 [PMID: 24260386] (Cell Culture, Human) |
Cell Culture |
Human |
| McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma. PLoS ONE, 2013-11-11;8(11):e78728. 2013-11-11 [PMID: 24244348] (Cell Culture, Human) |
Cell Culture |
Human |
| Csaszar , Elizabet, Wang , Weijia, Usenko , Tatiana, Qiao , Wenlian, Delaney , Colleen, Bernstein , Irwin D, Zandstra , Peter W Blood stem cell fate regulation by Delta-1-mediated rewiring of IL-6 paracrine signaling. Blood, 2013-11-15;123(5):650-8. 2013-11-15 [PMID: 24243972] (Bioassay, Human) |
Bioassay |
Human |
| Dowty , Martin E, Jesson , Michael, Ghosh , Sarbani, Lee , Jamie, Meyer , Debra M, Krishnaswami , Sriram, Kishore , Nandini Preclinical to clinical translation of tofacitinib, a Janus kinase inhibitor, in rheumatoid arthritis. J Pharmacol Exp Ther, 2013-11-11;348(1):165-73. 2013-11-11 [PMID: 24218541] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Mele V, Muraro M, Calabrese D, Pfaff D, Amatruda N, Amicarella F, Kvinlaug B, Bocelli-Tyndall C, Martin I, Resink T, Heberer M, Oertli D, Terracciano L, Spagnoli G, Iezzi G Mesenchymal stromal cells induce epithelial-to-mesenchymal transition in human colorectal cancer cells through the expression of surface-bound TGF-beta. Int J Cancer, 2014-01-30;134(11):2583-94. 2014-01-30 [PMID: 24214914] (Bioassay, Human) |
Bioassay |
Human |
| Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes. PLoS Pathog, 2013-10-17;9(10):e1003700. 2013-10-17 [PMID: 24204260] (Bioassay, Human) |
Bioassay |
Human |
| Todd J, Simpson P, Estis J, Torres V, Wub A Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays. Cytokine, 2013-10-12;64(3):660-5. 2013-10-12 [PMID: 24128872] (ELISA (Standard), Human) |
ELISA (Standard) |
Human |
| Doulatov S, Vo L, Chou S, Kim P, Arora N, Li H, Hadland B, Bernstein I, Collins J, Zon L, Daley G Induction of multipotential hematopoietic progenitors from human pluripotent stem cells via respecification of lineage-restricted precursors. Cell Stem Cell, 2013-10-03;13(4):459-70. 2013-10-03 [PMID: 24094326] (Bioassay, Human) |
Bioassay |
Human |
| Fletcher E, Love-Homan L, Sobhakumari A, Feddersen C, Koch A, Goel A, Simons A EGFR inhibition induces proinflammatory cytokines via NOX4 in HNSCC. Mol Cancer Res, 2013-09-18;11(12):1574-84. 2013-09-18 [PMID: 24048704] (Bioassay, Human) |
Bioassay |
Human |
| Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, Bredel M, Benveniste E Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma. Clin Cancer Res, 2013-09-13;19(23):6484-94. 2013-09-13 [PMID: 24036851] (Cell Culture, Human) |
Cell Culture |
Human |
| Minami J, Suzuki R, Mazitschek R, Gorgun G, Ghosh B, Cirstea D, Hu Y, Mimura N, Ohguchi H, Cottini F, Jakubikova J, Munshi N, Haggarty S, Richardson P, Hideshima T, Anderson K Histone deacetylase 3 as a novel therapeutic target in multiple myeloma. Leukemia, 2013-08-05;28(3):680-9. 2013-08-05 [PMID: 23913134] (Bioassay, Human) |
Bioassay |
Human |
| Yoo H, Seo J, Yoo J CTR9, a component of PAF complex, controls elongation block at the c-Fos locus via signal-dependent regulation of chromatin-bound NELF dissociation. PLoS ONE, 2013-04-11;8(4):e61055. 2013-04-11 [PMID: 23593388] (Bioassay, Human) |
Bioassay |
Human |
| El-Zaatari M, Kao J, Tessier A, Bai L, Hayes M, Fontaine C, Eaton K, Merchant J Gli1 deletion prevents Helicobacter-induced gastric metaplasia and expansion of myeloid cell subsets. PLoS ONE, 2013-03-08;8(3):e58935. 2013-03-08 [PMID: 23520544] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Melemedjian O, Tillu D, Asiedu M, Mandell E, Moy J, Blute V, Taylor C, Ghosh S, Price T BDNF regulates atypical PKC at spinal synapses to initiate and maintain a centralized chronic pain state. Mol Pain, 2013-03-20;9(0):12. 2013-03-20 [PMID: 23510079] (In Vivo, Mouse) |
In Vivo |
Mouse |
| Malaponte G, Polesel J, Candido S, Sambataro D, Bevelacqua V, Anzaldi M, Vella N, Fiore V, Militello L, Mazzarino M, Libra M, Signorelli S IL-6-174 G > C and MMP-9-1562 C > T polymorphisms are associated with increased risk of deep vein thrombosis in cancer patients. Cytokine, 2013-03-11;62(1):64-9. 2013-03-11 [PMID: 23490413] (Bioassay, Human) |
Bioassay |
Human |
| Yu , Jianhua, Peng , Yong, Wu , Lai-Chu, Xie , Zhiliang, Deng , Youcai, Hughes , Tiffany, He , Shun, Mo , XiaoKui, Chiu , Ming, Wang , Qi-En, He , Xiaoming, Liu , Shujun, Grever , Michael, Chan , Kenneth, Liu , Zhongfa Curcumin down-regulates DNA methyltransferase 1 and plays an anti-leukemic role in acute myeloid leukemia. PLoS ONE, 2013-02-13;8(2):e55934. 2013-02-13 [PMID: 23457487] (Bioassay, Human) |
Bioassay |
Human |
| Leone E, Morelli E, Di Martino M, Amodio N, Foresta U, Gulla A, Rossi M, Neri A, Giordano A, Munshi N, Anderson K, Tagliaferri P, Tassone P Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth. Clin Cancer Res, 2013-02-27;19(8):2096-106. 2013-02-27 [PMID: 23446999] (Bioassay, Human) |
Bioassay |
Human |
| Srivastava R, Lee S, Andrade Filho P, Lord C, Jie H, Davidson H, Lopez-Albaitero A, Gibson S, Gooding W, Ferrone S, Ferris R Cetuximab-activated natural killer and dendritic cells collaborate to trigger tumor antigen-specific T-cell immunity in head and neck cancer patients. Clin Cancer Res, 2013-02-26;19(7):1858-72. 2013-02-26 [PMID: 23444227] (Bioassay, Human) |
Bioassay |
Human |
| Verjee L, Verhoekx J, Chan J, Krausgruber T, Nicolaidou V, Izadi D, Davidson D, Feldmann M, Midwood K, Nanchahal J Unraveling the signaling pathways promoting fibrosis in Dupuytren's disease reveals TNF as a therapeutic target. Proc Natl Acad Sci U S A, 2013-02-19;110(10):E928-37. 2013-02-19 [PMID: 23431165] (Bioassay, Human) |
Bioassay |
Human |
| Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S Protein carbamylation predicts mortality in ESRD. 2013-02-21;0(0):. 2013-02-21 [PMID: 23431074] (ELISA (Standard), Human) |
ELISA (Standard) |
Human |
| Giannoni F, Hardee C, Wherley J, Gschweng E, Senadheera S, Kaufman M, Chan R, Bahner I, Gersuk V, Wang X, Gjertson D, Baltimore D, Witte O, Economou J, Ribas A, Kohn D Allelic exclusion and peripheral reconstitution by TCR transgenic T cells arising from transduced human hematopoietic stem/progenitor cells. Mol Ther, 2013-02-05;21(5):1044-54. 2013-02-05 [PMID: 23380815] (Bioassay, Human) |
Bioassay |
Human |
| Johnston A, Xing X, Swindell W, Kochkodan J, Riblett M, Nair R, Stuart P, Ding J, Voorhees J, Elder J, Gudjonsson J Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis. Hum Mol Genet, 2013-01-31;22(9):1807-15. 2013-01-31 [PMID: 23376980] (Bioassay, Human) |
Bioassay |
Human |
| Park J, Lim M, Cho M, Ryu J, Moon Y, Jhun J, Byun J, Kim E, Hwang S, Ju J, Kwok S, Kim H p53 controls autoimmune arthritis via STAT-mediated regulation of the Th17 cell/Treg cell balance in mice. Arthritis Rheum, 2013-04-01;65(4):949-59. 2013-04-01 [PMID: 23280308] (Bioassay, Human) |
Bioassay |
Human |
| Gemperle C, Schmid M, Herova M, Marti-Jaun J, Wuest S, Loretz C, Hersberger M Regulation of the formyl peptide receptor 1 (FPR1) gene in primary human macrophages. PLoS ONE, 2012-11-21;7(11):e50195. 2012-11-21 [PMID: 23185575] (Bioassay, Human) |
Bioassay |
Human |
| Kothari H, Rao L, Vankayalapati R, Pendurthi U Mycobacterium tuberculosis infection and tissue factor expression in macrophages. PLoS ONE, 2012-09-24;7(9):e45700. 2012-09-24 [PMID: 23029190] (Bioassay, Human) |
Bioassay |
Human |
| Zelinka C, Scott M, Volkov L, Fischer A The reactivity, distribution and abundance of Non-astrocytic Inner Retinal Glial (NIRG) cells are regulated by microglia, acute damage, and IGF1. PLoS ONE, 2012-09-04;7(9):e44477. 2012-09-04 [PMID: 22973454] (In Vivo, Chicken) |
In Vivo |
Chicken |
| CD4 T follicular helper cell dynamics during SIV infection. J. Clin. Invest., 2012-08-27;122(9):3281-94. 2012-08-27 [PMID: 22922258] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure. Oncoimmunology, 2012-03-01;1(2):129-140. 2012-03-01 [PMID: 22720234] (Bioassay, Human) |
Bioassay |
Human |
| Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase. J. Biol. Chem., 2012-06-11;287(31):25964-74. 2012-06-11 [PMID: 22689578] (Bioassay, Human) |
Bioassay |
Human |
| Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation. Eur. J. Immunol., 2012-04-01;42(4):936-45. 2012-04-01 [PMID: 22531918] (Bioassay, Human) |
Bioassay |
Human |
| Zielinski CE, Mele F, Aschenbrenner D, Jarrossay D, Ronchi F, Gattorno M, Monticelli S, Lanzavecchia A, Sallusto F Pathogen-induced human TH17 cells produce IFN-gamma or IL-10 and are regulated by IL-1beta. Nature, 2012-04-26;484(7395):514-8. 2012-04-26 [PMID: 22466287] (Bioassay, Human) |
Bioassay |
Human |
| Hong YS, Moon SJ, Moon S, Joo YB, Joo Y, Jeon CH, Jeon C, Cho ML, Ju JH, Oh HJ, Heo YJ, Heo Y, Park SH, Kim HY, Min JK Measurement of interleukin-33 (IL-33) and IL-33 receptors (sST2 and ST2L) in patients with rheumatoid arthritis. J Korean Med Sci, 2011-09-01;26(9):1132-9. 2011-09-01 [PMID: 21935266] (ELISA (Standard)) |
ELISA (Standard) |
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| Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli. J. Immunol., 2011-05-04;186(12):6701-9. 2011-05-04 [PMID: 21543643] (Bioassay, Human) |
Bioassay |
Human |
| Liao W, Lin JX, Wang L, Li P, Leonard WJ Modulation of cytokine receptors by IL-2 broadly regulates differentiation into helper T cell lineages. Nat. Immunol., 2011-04-24;12(6):551-9. 2011-04-24 [PMID: 21516110] (Bioassay, Human, Mouse) |
Bioassay |
Human, Mouse |
| Steinbicker AU, Sachidanandan C, Vonner AJ Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation. Blood, 2011-03-10;117(18):4915-23. 2011-03-10 [PMID: 21393479] (Bioassay, Human) |
Bioassay |
Human |
| Hosomi S, Oshitani N, Kamata N, Sogawa M, Okazaki H, Tanigawa T, Yamagami H, Watanabe K, Tominaga K, Watanabe T, Fujiwara Y, Maeda K, Hirakawa K, Arakawa T Increased numbers of immature plasma cells in peripheral blood specifically overexpress chemokine receptor CXCR3 and CXCR4 in patients with ulcerative colitis. Clin. Exp. Immunol., 2010-11-19;163(2):215-24. 2010-11-19 [PMID: 21087446] (Bioassay, Human) |
Bioassay |
Human |
| Xu H, Wang X, Pahar B Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression. J. Immunol., 2010-11-08;185(12):7340-8. 2010-11-08 [PMID: 21059890] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Tolar J, Park I, Xia L, Lees C, Peacock B, Webber B, McElmurry R, Eide C, Orchard P, Kyba M, Osborn M, Lund T, Wagner J, Daley G, Blazar B Hematopoietic differentiation of induced pluripotent stem cells from patients with mucopolysaccharidosis type I (Hurler syndrome). Blood, 2010-10-29;117(3):839-47. 2010-10-29 [PMID: 21037085] (Bioassay, Human) |
Bioassay |
Human |
| Jones GW, Stumhofer JS, Foster T, Twohig JP, Hertzog P, Topley N, Williams AS, Hunter CA, Jenkins BJ, Wang EC, Jones SA Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation. FASEB J., 2010-09-08;25(1):409-19. 2010-09-08 [PMID: 20826539] (Bioassay, Human) |
Bioassay |
Human |
| Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice. J. Immunol., 2010-07-16;185(0):2516-24. 2010-07-16 [PMID: 20639493] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Narazaki M, Segarra M, Hou X, Tanaka T, Li X, Tosato G Oligo-guanosine nucleotide induces neuropilin-1 internalization in endothelial cells and inhibits angiogenesis. Blood, 2010-07-06;116(16):3099-107. 2010-07-06 [PMID: 20606164] (Bioassay, Human) |
Bioassay |
Human |
| Trowbridge JJ, Guezguez B, Moon RT Wnt3a activates dormant c-Kit(-) bone marrow-derived cells with short-term multilineage hematopoietic reconstitution capacity. Stem Cells, 2010-08-01;28(8):1379-89. 2010-08-01 [PMID: 20521329] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Morizane S, Yamasaki K, Kabigting FD, Gallo RL Kallikrein expression and cathelicidin processing are independently controlled in keratinocytes by calcium, vitamin D(3), and retinoic acid. J. Invest. Dermatol., 2010-01-21;130(5):1297-306. 2010-01-21 [PMID: 20090765] (Bioassay, Human) |
Bioassay |
Human |
| Liu X, Leung S, Wang C, Tan Z, Wang J, Guo TB, Fang L, Zhao Y, Wan B, Qin X, Lu L, Li R, Pan H, Song M, Liu A, Hong J, Lu H, Zhang JZ Crucial role of interleukin-7 in T helper type 17 survival and expansion in autoimmune disease. Nat. Med., 2010-01-10;16(2):191-7. 2010-01-10 [PMID: 20062065] (Bioassay, Human) |
Bioassay |
Human |
| Lee WW, Kang SW, Choi J Regulating human Th17 cells via differential expression of IL-1 receptor. Blood, 2009-11-12;115(3):530-40. 2009-11-12 [PMID: 19965648] (Bioassay, Human) |
Bioassay |
Human |
| Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients. Immunol. Lett., 2009-11-04;127(2):150-6. 2009-11-04 [PMID: 19895848] (Bioassay, Human) |
Bioassay |
Human |
| Funderburg NT, Mayne E, Sieg SF Increased tissue factor expression on circulating monocytes in chronic HIV infection: relationship to in vivo coagulation and immune activation. Blood, 2009-10-14;115(2):161-7. 2009-10-14 [PMID: 19828697] (Bioassay, Human) |
Bioassay |
Human |
| Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases. J. Immunol., 2009-07-10;183(3):1739-50. 2009-07-10 [PMID: 19592653] (Bioassay, Human) |
Bioassay |
Human |
| Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells. Nat. Immunol., 2009-07-05;10(8):857-63. 2009-07-05 [PMID: 19578369] (Bioassay, Human) |
Bioassay |
Human |
| Ye L, Chang JC, Lin C, Sun X, Yu J, Kan YW Induced pluripotent stem cells offer new approach to therapy in thalassemia and sickle cell anemia and option in prenatal diagnosis in genetic diseases. Proc. Natl. Acad. Sci. U.S.A., 2009-05-29;106(24):9826-30. 2009-05-29 [PMID: 19482945] (Bioassay, Human) |
Bioassay |
Human |
| Niu KC, Huang WT, Lin MT, Huang KF Hyperbaric oxygen causes both antiinflammation and antipyresis in rabbits. Eur. J. Pharmacol., 2009-01-21;606(1):240-5. 2009-01-21 [PMID: 19374861] (In Vivo, Rabbit) |
In Vivo |
Rabbit |
| Aliahmadi E, Gramlich R, Grutzkau A, Hitzler M, Kruger M, Baumgrass R, Schreiner M, Wittig B, Wanner R, Peiser M TLR2-activated human langerhans cells promote Th17 polarization via IL-1beta, TGF-beta and IL-23. Eur. J. Immunol., 2009-05-01;39(5):1221-30. 2009-05-01 [PMID: 19350551] (Bioassay, Human) |
Bioassay |
Human |
| Boniface K, Bak-Jensen KS, Li Y, Blumenschein WM, McGeachy MJ, McClanahan TK, McKenzie BS, Kastelein RA, Cua DJ, de Waal Malefyt R Prostaglandin E2 regulates Th17 cell differentiation and function through cyclic AMP and EP2/EP4 receptor signaling. J. Exp. Med., 2009-03-09;206(3):535-48. 2009-03-09 [PMID: 19273625] (Bioassay, Mouse) |
Bioassay |
Mouse |
| Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts. Bone, 2009-03-02;44(6):1143-50. 2009-03-02 [PMID: 19264156] (Bioassay, Human) |
Bioassay |
Human |
| Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells. Circulation, 2009-03-02;119(10):1424-32. 2009-03-02 [PMID: 19255340] (Bioassay, Human) |
Bioassay |
Human |
| Yammani RR, Long D, Loeser RF Interleukin-7 stimulates secretion of S100A4 by activating the JAK/STAT signaling pathway in human articular chondrocytes. Arthritis Rheum., 2009-03-01;60(3):792-800. 2009-03-01 [PMID: 19248116] (Bioassay, Human) |
Bioassay |
Human |
| Mizutani K, Sud S, Pienta KJ Prostate cancer promotes CD11b positive cells to differentiate into osteoclasts. J. Cell. Biochem., 2009-03-01;106(4):563-9. 2009-03-01 [PMID: 19170075] (Bioassay, Human) |
Bioassay |
Human |
| Ara T, Song L, Shimada H, Keshelava N, Russell HV, Metelitsa LS, Groshen SG, Seeger RC, DeClerck YA Interleukin-6 in the bone marrow microenvironment promotes the growth and survival of neuroblastoma cells. Cancer Res., 2009-01-01;69(1):329-37. 2009-01-01 [PMID: 19118018] (Bioassay, Human) |
Bioassay |
Human |
| Eyerich K, Pennino D, Scarponi C, Foerster S, Nasorri F, Behrendt H, Ring J, Traidl-Hoffmann C, Albanesi C, Cavani A IL-17 in atopic eczema: linking allergen-specific adaptive and microbial-triggered innate immune response. J. Allergy Clin. Immunol., 2008-12-03;123(1):59-66.e4. 2008-12-03 [PMID: 19056110] (Bioassay, Human) |
Bioassay |
Human |
| Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts. Arthritis Rheum., 2008-12-01;58(12):3820-30. 2008-12-01 [PMID: 19035475] (Bioassay, Human) |
Bioassay |
Human |
| Ahmed S, Marotte H, Kwan K, Ruth JH, Campbell PL, Rabquer BJ, Pakozdi A, Koch AE Epigallocatechin-3-gallate inhibits IL-6 synthesis and suppresses transsignaling by enhancing soluble gp130 production. Proc. Natl. Acad. Sci. U.S.A., 2008-09-16;105(38):14692-7. 2008-09-16 [PMID: 18796608] (Bioassay, Human) |
Bioassay |
Human |
| Kolliputi N, Waxman AB IL-6 cytoprotection in hyperoxic acute lung injury occurs via suppressor of cytokine signaling-1-induced apoptosis signal-regulating kinase-1 degradation. Am. J. Respir. Cell Mol. Biol., 2008-09-05;40(3):314-24. 2008-09-05 [PMID: 18776134] (Bioassay, Human) |
Bioassay |
Human |
| Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6. J. Immunol., 2008-08-15;181(4):2772-80. 2008-08-15 [PMID: 18684968] (Bioassay, Human) |
Bioassay |
Human |
| Osei-Kumah A, Smith R, Clifton VL Maternal and cord plasma cytokine and chemokine profile in pregnancies complicated by asthma. Cytokine, 2008-07-17;43(2):187-93. 2008-07-17 [PMID: 18639465] (ELISA (Standard)) |
ELISA (Standard) |
|
| Gerber SA, Pober JS IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells. J. Immunol., 2008-07-15;181(2):1052-62. 2008-07-15 [PMID: 18606657] (Bioassay, Human) |
Bioassay |
Human |
| Jasny E, Eisenblatter M, Matz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation. J. Immunol., 2008-05-15;180(10):6629-39. 2008-05-15 [PMID: 18453582] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps. J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392. 2008-04-14 [PMID: 18410958] (Bioassay, Human) |
Bioassay |
Human |
| Chong DY, Boehlke CS, Zheng QD, Zhang L, Han Y, Zacks DN Interleukin-6 as a photoreceptor neuroprotectant in an experimental model of retinal detachment. Invest. Ophthalmol. Vis. Sci., 2008-03-31;49(7):3193-200. 2008-03-31 [PMID: 18378582] (In Vivo, Mouse, Rat) |
In Vivo |
Mouse, Rat |
| Gunetti M, Ferrero I, Rustichelli D, Berger M, Gammaitoni L, Timeus F, Piacibello W, Aglietta M, Fagioli F Refreezing of cord blood hematopoietic stem cells for allogenic transplantation: in vitro and in vivo validation of a clinical phase I/II protocol in European and Italian Good Manufacturing Practice conditions. Exp. Hematol., 2008-02-01;36(2):235-43. 2008-02-01 [PMID: 18206730] (Bioassay, Human) |
Bioassay |
Human |
| Yang HT, Cohen P, Rousseau S IL-1beta-stimulated activation of ERK1/2 and p38alpha MAPK mediates the transcriptional up-regulation of IL-6, IL-8 and GRO-alpha in HeLa cells. Cell. Signal., 2007-11-07;20(2):375-80. 2007-11-07 [PMID: 18065201] (Bioassay, Human) |
Bioassay |
Human |
| Liotta F, Angeli R, Cosmi L, Fili L, Manuelli C, Frosali F, Mazzinghi B, Maggi L, Pasini A, Lisi V, Santarlasci V, Consoloni L, Angelotti ML, Romagnani P, Parronchi P, Krampera M, Maggi E, Romagnani S, Annunziato F Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells, 2007-10-25;26(1):279-89. 2007-10-25 [PMID: 17962701] (ELISA (Standard)) |
ELISA (Standard) |
|
| Neri P, Kumar S, Fulciniti MT, Vallet S, Chhetri S, Mukherjee S, Tai Y, Chauhan D, Tassone P, Venuta S, Munshi NC, Hideshima T, Anderson KC, Raje N Neutralizing B-cell activating factor antibody improves survival and inhibits osteoclastogenesis in a severe combined immunodeficient human multiple myeloma model. Clin. Cancer Res., 2007-10-01;13(19):5903-9. 2007-10-01 [PMID: 17908986] (Bioassay, Human) |
Bioassay |
Human |
| Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P Ultrasensitive flow-based immunoassays using single-molecule counting. Clin. Chem., 2007-09-21;53(11):1990-5. 2007-09-21 [PMID: 17890441] (ELISA (Standard)) |
ELISA (Standard) |
|
| Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration. J. Biol. Chem., 2007-08-24;282(43):31643-55. 2007-08-24 [PMID: 17720976] (Bioassay, Human) |
Bioassay |
Human |
| Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques. Transplantation, 2007-07-27;84(2):196-206. 2007-07-27 [PMID: 17667811] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Luty WH, Rodeberg D, Parness J, Vyas YM Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates. J. Immunol., 2007-07-15;179(2):819-29. 2007-07-15 [PMID: 17617572] (Bioassay, Human) |
Bioassay |
Human |
| Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest. Ophthalmol. Vis. Sci., 2007-06-01;48(6):2634-43. 2007-06-01 [PMID: 17525194] (Bioassay, Human) |
Bioassay |
Human |
| Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease. J. Immunol., 2007-05-01;178(9):5973-81. 2007-05-01 [PMID: 17442982] (Bioassay, Human) |
Bioassay |
Human |
| Gross M, Top I, Laux I, Katz J, Curran J, Tindell C, Agus D Beta-2-microglobulin is an androgen-regulated secreted protein elevated in serum of patients with advanced prostate cancer. Clin. Cancer Res., 2007-04-01;13(7):1979-86. 2007-04-01 [PMID: 17404077] (Bioassay, Human) |
Bioassay |
Human |
| van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers. Dig. Dis. Sci., 2007-03-30;52(10):2775-83. 2007-03-30 [PMID: 17394066] (Bioassay, Human) |
Bioassay |
Human |
| Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. Int. J. Oncol., 2007-04-01;30(4):977-83. 2007-04-01 [PMID: 17332938] (Bioassay, Human) |
Bioassay |
Human |
| Brechter AB, Lerner UH Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis Rheum., 2007-03-01;56(3):910-23. 2007-03-01 [PMID: 17328065] (Bioassay, Human) |
Bioassay |
Human |
| Ettinger R, Sims GP, Robbins R, Withers D, Fischer RT, Grammer AC, Kuchen S, Lipsky PE IL-21 and BAFF/BLyS synergize in stimulating plasma cell differentiation from a unique population of human splenic memory B cells. J. Immunol., 2007-03-01;178(5):2872-82. 2007-03-01 [PMID: 17312131] (Bioassay, Human) |
Bioassay |
Human |
| Rajesh</LastName><ForeNam D</Initial, Rajesh D, Chinnasamy N, Mitalipov SM, Wolf DP, Slukvin I, Thomson JA, Shaaban AF Differential requirements for hematopoietic commitment between human and rhesus embryonic stem cells. Stem Cells, 2007-02-01;25(2):490-9. 2007-02-01 [PMID: 17284653] (Bioassay, Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Human, Mouse, Primate - Macaca mulatta (Rhesus Macaque) |
| Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med., 2006-11-20;203(12):2763-77. 2006-11-20 [PMID: 17116732] (Bioassay, Human) |
Bioassay |
Human |
| Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes. J. Immunol., 2006-12-01;177(11):7665-72. 2006-12-01 [PMID: 17114436] (Bioassay, Human) |
Bioassay |
Human |
| Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators. Crit. Care Med., 2007-01-01;35(1):199-206. 2007-01-01 [PMID: 17110873] (Bioassay, Bovine, Human) |
Bioassay |
Bovine, Human |
| Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression. J. Endocrinol., 2006-10-01;191(1):65-81. 2006-10-01 [PMID: 17065390] (Bioassay, Hamster) |
Bioassay |
Hamster |
| Ammit AJ, Moir LM, Oliver BG, Hughes JM, Alkhouri H, Ge Q, Burgess JK, Black JL, Roth M Effect of IL-6 trans-signaling on the pro-remodeling phenotype of airway smooth muscle. Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-25;292(1):L199-206. 2006-08-25 [PMID: 16936245] (Bioassay, Human) |
Bioassay |
Human |
| Kiryushko D, Pavon L, Novitskaya V, Sandoval-Lopez G, Soroka V, Eugenia Hernandez M, Klingelhofer J, Loria F, Lukanidin E, Estrada I, Berezin V, Perez M, Bock E, Moreno J, Avila U, Leff P, Anton B, Heinze G Th2 cytokine response in Major Depressive Disorder patients before treatment. J. Neuroimmunol., 2006-02-02;172(1):156-65. 2006-02-02 [PMID: 16457895] (ELISA (Standard)) |
ELISA (Standard) |
|
| Gemelli C, Montanari M, Tenedini E, Zanocco Marani T, Vignudelli T, Siena M, Zini R, Salati S, Tagliafico E, Manfredini R, Grande A, Ferrari S Virally mediated MafB transduction induces the monocyte commitment of human CD34+ hematopoietic stem/progenitor cells. Cell Death Differ., 2006-02-03;13(10):1686-96. 2006-02-03 [PMID: 16456583] (Bioassay, Human) |
Bioassay |
Human |
| Mortara L, Ploquin MJ, Faye A, Scott-Algara D, Vaslin B, Butor C, Hosmalin A, Barre-Sinoussi F, Diop OM, Muller-Trutwin MC Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes. J. Immunol. Methods, 2005-11-21;308(1):138-55. 2005-11-21 [PMID: 16325847] (Bioassay, Primate - Chlorocebus pygerythrus (Vervet Monkey)) |
Bioassay |
Primate - Chlorocebus pygerythrus (Vervet Monkey) |
| von Strandmann EP, Hansen HP, Reiners KS, Schnell R, Borchmann P, Merkert S, Simhadri VR, Draube A, Reiser M, Purr I, Hallek M, Engert A A novel bispecific protein (ULBP2-BB4) targeting the NKG2D receptor on natural killer (NK) cells and CD138 activates NK cells and has potent antitumor activity against human multiple myeloma in vitro and in vivo. Blood, 2005-10-06;107(5):1955-62. 2005-10-06 [PMID: 16210338] (Bioassay, Human) |
Bioassay |
Human |
| Hsieh FH, Sharma P, Gibbons A, Goggans T, Erzurum SC, Haque SJ Human airway epithelial cell determinants of survival and functional phenotype for primary human mast cells. Proc. Natl. Acad. Sci. U.S.A., 2005-09-26;102(40):14380-5. 2005-09-26 [PMID: 16186496] (Bioassay, Human) |
Bioassay |
Human |
| Hanley MB, Napolitano LA, McCune JM Growth hormone-induced stimulation of multilineage human hematopoiesis. Stem Cells, 2005-06-13;23(8):1170-9. 2005-06-13 [PMID: 15955828] (Bioassay, Human) |
Bioassay |
Human |
| Holst RM, Mattsby-Baltzer I, Wennerholm UB, Hagberg H, Jacobsson B Interleukin-6 and interleukin-8 in cervical fluid in a population of Swedish women in preterm labor: relationship to microbial invasion of the amniotic fluid, intra-amniotic inflammation, and preterm delivery. Acta Obstet Gynecol Scand, 2005-06-01;84(6):551-7. 2005-06-01 [PMID: 15901266] (ELISA (Standard)) |
ELISA (Standard) |
|
| Mandelin J, Li TF, Hukkanen M, Liljestrom M, Salo J, Santavirta S, Konttinen YT Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K. J. Rheumatol., 2005-04-01;32(4):713-20. 2005-04-01 [PMID: 15801030] (Bioassay, Human) |
Bioassay |
Human |
| Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC trans fatty acids and systemic inflammation in heart failure. Am. J. Clin. Nutr., 2004-12-01;80(6):1521-5. 2004-12-01 [PMID: 15585763] (ELISA (Standard)) |
ELISA (Standard) |
|
| Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, Bougras G, Muller WA, Moretta L, Munz C Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs. Proc. Natl. Acad. Sci. U.S.A., 2004-11-09;101(47):16606-11. 2004-11-09 [PMID: 15536127] (Bioassay, Human) |
Bioassay |
Human |
| Nagineni CN, Kutty V, Detrick B, Hooks JJ Expression of PDGF and their receptors in human retinal pigment epithelial cells and fibroblasts: regulation by TGF-beta. J. Cell. Physiol., 2005-04-01;203(1):35-43. 2005-04-01 [PMID: 15368539] (Bioassay, Human) |
Bioassay |
Human |
| Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-09-01;173(5):3482-91. 2004-09-01 [PMID: 15322213] (Bioassay, Human) |
Bioassay |
Human |
| Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R IL-22 increases the innate immunity of tissues. Immunity, 2004-08-01;21(2):241-54. 2004-08-01 [PMID: 15308104] (Bioassay, Human) |
Bioassay |
Human |
| Phillips TM Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis. Electrophoresis, 2004-06-01;25(10):1652-9. 2004-06-01 [PMID: 15188254] |
|
|
| Larsson M, Babcock E, Grakoui A, Shoukry N, Lauer G, Rice C, Walker C, Bhardwaj N Lack of phenotypic and functional impairment in dendritic cells from chimpanzees chronically infected with hepatitis C virus. J. Virol., 2004-06-01;78(12):6151-61. 2004-06-01 [PMID: 15163708] (Bioassay, Primate - Pan troglodytes (Chimpanzee)) |
Bioassay |
Primate - Pan troglodytes (Chimpanzee) |
| Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C CD14 is an acute-phase protein. J. Immunol., 2004-04-01;172(7):4470-9. 2004-04-01 [PMID: 15034063] (Bioassay, Human) |
Bioassay |
Human |
| Copeland S, Siddiqui J, Remick D Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines. J. Immunol. Methods, 2004-01-01;284(1):99-106. 2004-01-01 [PMID: 14736420] (ELISA (Standard)) |
ELISA (Standard) |
|
| McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation. J. Clin. Invest., 2003-08-01;112(4):598-607. 2003-08-01 [PMID: 12925700] (ELISA (Standard)) |
ELISA (Standard) |
|
| Hurst SM, McLoughlin RM, Monslow J, Owens S, Morgan L, Fuller GM, Topley N, Jones SA Secretion of oncostatin M by infiltrating neutrophils: regulation of IL-6 and chemokine expression in human mesothelial cells. J. Immunol., 2002-11-01;169(9):5244-51. 2002-11-01 [PMID: 12391243] (ELISA (Standard)) |
ELISA (Standard) |
|
| Erices A, Conget P, Rojas C, Minguell JJ Gp130 activation by soluble interleukin-6 receptor/interleukin-6 enhances osteoblastic differentiation of human bone marrow-derived mesenchymal stem cells. Exp. Cell Res., 2002-10-15;280(1):24-32. 2002-10-15 [PMID: 12372336] (Bioassay, Human) |
Bioassay |
Human |
| Cork BA, 146, Tuckerman EM, Li TC, Laird SM Expression of interleukin (IL)-11 receptor by the human endometrium in vivo and effects of IL-11, IL-6 and LIF on the production of MMP and cytokines by human endometrial cells in vitro. 2002-09-01;8(9):841-8. 2002-09-01 [PMID: 12200462] (Bioassay, Human) |
Bioassay |
Human |
| Manz MG, 107325, Miyamoto T, Akashi K, Weissman IL Prospective isolation of human clonogenic common myeloid progenitors. Ultra-Sensitive and Semi-Quantitative Vertical Flow Assay for the Rapid Detection of Interleukin-6 in Inflammatory Diseases, 2002-08-22;99(18):11872-7. 2002-08-22 [PMID: 12193648] (Bioassay, Human) |
Bioassay |
Human |
| Shih CC, Hu MC, Hu J A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells. Blood, 2000-03-15;95(6):1957-66. 2000-03-15 [PMID: 10706861] (Bioassay, Human) |
Bioassay |
Human |
| Gomez-Navarro J, ¯&h~²@á, Contreras JL, Arafat W, Jiang XL, Krisky D, Oligino T, Marconi P, Hubbard B, Glorioso JC, Curiel DT, Thomas JM Genetically modified CD34+ cells as cellular vehicles for gene delivery into areas of angiogenesis in a rhesus model. 2000-01-01;7(1):43-52. 2000-01-01 [PMID: 10680015] (Bioassay, Primate - Macaca mulatta (Rhesus Macaque)) |
Bioassay |
Primate - Macaca mulatta (Rhesus Macaque) |
| Akagi Y, Liu W, Zebrowski B, Xie K, Ellis LM Regulation of vascular endothelial growth factor expression in human colon cancer by insulin-like growth factor-I. Cancer Res., 1998-09-01;58(17):4008-14. 1998-09-01 [PMID: 9731515] (Bioassay, Human) |
Bioassay |
Human |
| Barcena A, Park SW, Banapour B, Muench MO, Mechetner E Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver. Blood, 1996-09-15;88(6):2013-25. 1996-09-15 [PMID: 8822920] (Bioassay, Human) |
Bioassay |
Human |
|
Show All 351 Publications.
Collapse Publications.
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![Neutralization CXCL8/IL-8 Antibody (6217) [Unconjugated]](https://images.novusbio.com/images2/CXCL8_MAB208_Block_Neutralize_9064.jpg)
![Immunocytochemistry CXCL8/IL-8 Antibody (6217) [Unconjugated]](https://images.novusbio.com/images2/CXCL8_MAB208_Immunocytochemistry_9339.jpg)
![Western Blot CXCL8/IL-8 Antibody (6217) [Unconjugated]](https://images.novusbio.com/images2/mab208_human-il-8-cxcl8-mab-clone-6217-western-blot-1882021143847.jpg)
![SDS-PAGE TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNF-alpha_210-TA_256.jpg)
![Bioactivity TNF-alpha [Unconjugated]](https://images.novusbio.com/images2/TNFalpha_210TA_1658.jpg)
![SEC-MALS TNF-alpha [Unconjugated]](https://images.novusbio.com/images/210-ta_recombinant-human-tnf-alpha-protein-sec-mals-35202312244..jpg)
![N/A IL-10 [Biotin]](https://images.novusbio.com/images2/DATA_IL10_DY417_ELISA_2014.jpg)
![N/A C-Reactive Protein/CRP [Biotin]](https://images.novusbio.com/images2/DATA_CReactive_Protein_DY1707_ELISA_1701.jpg)
![SDS-PAGE IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_304.jpg)
![Bioactivity IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images2/IL-1_beta_201-LB_306.jpg)
![SEC-MALS IL-1 beta/IL-1F2 [Unconjugated]](https://images.novusbio.com/images/201-lb_recombinant-human-il-1-beta-il-1f2-protein-sec-mals-123202491556.jpg)
![Bioactivity IL-2 [Unconjugated]](https://images.novusbio.com/images/202-il_recombinant-human-il-2-protein-bioactivity-174202314946.jpg)
![Bioactivity IL-4 [Unconjugated]](https://images.novusbio.com/images/protein/6507-ilcf_recombinant-human-il-4-cho-expressed-protein-cf-bioactivity-272020133214.jpg)
![Bioactivity IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFNgamma_285IF_2848.jpg)
![SDS-PAGE IFN-gamma [Unconjugated]](https://images.novusbio.com/images2/IFN-gamma_285-IF_230.jpg)
![SEC-MALS IFN-gamma [Unconjugated]](https://images.novusbio.com/images/285-if_recombinant-human-ifn-gamma-protein-sec-mals-1520239228..jpg)
![Knockout Validated STAT3 Antibody (232209) [Unconjugated]](https://images.novusbio.com/images2/STAT3_MAB1799_Simple_Western_21000.jpg)
![Western Blot STAT3 Antibody (232209) [Unconjugated]](https://images.novusbio.com/images2/STAT3_MAB1799_Western_Blot_5993.jpg)
![Knockout Validated STAT3 Antibody (232209) [Unconjugated]](https://images.novusbio.com/images2/STAT3_MAB1799_Knockout_Validated_21531.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/CCL2_DCP00_ELISA_67.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_633.jpg)
![N/A CCL2/JE/MCP-1 [HRP]](https://images.novusbio.com/images2/DATA_CCL2_DCP00_ELISA_634.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_871.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/DATA_VEGF_DVE00_ELISA_872.jpg)
![N/A VEGF [HRP]](https://images.novusbio.com/images2/VEGF_DVE00_ELISA_208.jpg)
![SDS-PAGE IL-3 [Unconjugated]](https://images.novusbio.com/images2/IL-3_203-IL_345.jpg)
![Bioactivity IL-3 [Unconjugated]](https://images.novusbio.com/images2/IL-3_203-IL_347.jpg)
![SEC-MALS IL-3 [Unconjugated]](https://images.novusbio.com/images/203-il_recombinant-human-il-3-protein-sec-mals-133202482656..jpg)
![Bioactivity GM-CSF [Unconjugated]](https://images.novusbio.com/images/protein/7954-gmcf_recombinant-human-gm-csf-cho-expressed-protein-cf-bioactivity-272020121514.jpg)