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Rat IL-6 DuoSet ELISA, 15 Plate

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Summary
Reactivity RtSpecies Glossary
Applications ELISA
Conjugate
Biotin

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Rat IL-6 DuoSet ELISA, 15 Plate Summary

Source
N/A
Assay Type
Solid Phase Sandwich ELISA
Inter-Assay
See PDF Datasheet for details
Intra-Assay
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details
Gene
Il6

Applications/Dilutions

Dilutions
  • ELISA
Application Notes
No significant interference observed with available related molecules.
Publications
Read Publications using
DY506 in the following applications:

Packaging, Storage & Formulations

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rat IL-6 DuoSet ELISA, 15 Plate

  • B-cell differentiation factor
  • B-cell stimulatory factor 2
  • BSF2
  • BSF-2
  • CDF
  • CTL differentiation factor
  • HSF
  • hybridoma growth factor
  • IFNB2
  • IFN-beta-2
  • IL6
  • IL-6
  • Interferon beta-2
  • interleukin 6 (interferon, beta 2)
  • interleukin BSF-2
  • interleukin-6
  • MGI-2A

Background

IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.

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DY506
Species: Rt
Applications: ELISA

Publications for IL-6 (DY506)(99)

We have publications tested in 2 confirmed species: Mouse, Rat.

We have publications tested in 1 application: ELISA Capture.


Filter By Application
ELISA Capture
(1)
All Applications
Filter By Species
Mouse
(2)
Rat
(97)
All Species
Showing Publications 1 - 10 of 99. Show All 99 Publications.
Publications using DY506 Applications Species
Souza, SS;Lopes Cruz, L;Alves-Reis, AM;Costa, VQ;Moraes-Souza, RQ;Damasceno, DC;Volpato, GT; Periodontitis and diabetes in pregnant rats: Maternal-fetal outcomes Heliyon 2024-09-15 [PMID: 39296079] (Rat) Rat
Chausse, B;Malorny, N;Lewen, A;Poschet, G;Berndt, N;Kann, O; Metabolic flexibility ensures proper neuronal network function in moderate neuroinflammation Scientific reports 2024-06-22 [PMID: 38909138] (Rat) Rat
Ferreira, RO;Pereira, MS;Souza-Monteiro, D;Frazão, DR;de Moura, JDM;Baia-da-Silva, DC;Bittencourt, LO;Balbinot, GS;Collares, FM;Lima, MLS;de Araújo, AA;Lima, RR; Physical training attenuates systemic cytokine response and tissue damage triggered by apical periodontitis Scientific reports 2024-04-05 [PMID: 38580668] (Rat) Rat
Rahman, Z;Shaikh, AS;Rao, KV;Dandekar, MP; Oxyberberine protects middle cerebral artery occlusion triggered cerebral injury through TLR4/NLRP3 pathway in rats Journal of chemical neuroanatomy 2024-01-19 [PMID: 38246265] (Rat) Rat
Anttila, JE;Mattila, OS;Liew, HK;Mätlik, K;Mervaala, E;Lindholm, P;Lindahl, M;Lindsberg, PJ;Tseng, KY;Airavaara, M; MANF protein expression is upregulated in immune cells in the ischemic human brain and systemic recombinant MANF delivery in rat ischemic stroke model demonstrates anti-inflammatory effects Acta neuropathologica communications 2024-01-16 [PMID: 38229173] (Rat) Rat
Sangweni, NF;Gabuza, K;van Aarde, R;Mabasa, L;van Vuuren, D;Huisamen, B;Barry, R;Johnson, R; Doxorubicin-Induced Cardiomyopathy: A Preliminary Study on the Cardioprotective Benefits of 7-Hydroxyflavanone International journal of molecular sciences 2023-10-20 [PMID: 37895075] (Rat) Rat
Xiao, Q;Chen, YH;Chen, YL;Chien, YS;Hsieh, LH;Shirakawa, H;Yang, SC; Potential Benefits of Epidermal Growth Factor for Inhibiting Muscle Degrative Markers in Rats with Alcoholic Liver Damage International journal of molecular sciences 2023-05-16 [PMID: 37240190] (Rat) Rat
Farahzadi, R;Fathi, E;Mesbah-Namin, SA;Vietor, I; Granulocyte differentiation of rat bone marrow resident C-kit+ hematopoietic stem cells induced by mesenchymal stem cells could be considered as new option in cell-based therapy Regenerative therapy 2023-06-01 [PMID: 37206538] (Rat) Rat
FL Haddad, C De Oliveir, S Schmid Investigating behavioral phenotypes related to autism spectrum disorder in a gene-environment interaction model of Cntnap2 deficiency and Poly I:C maternal immune activation Frontiers in Neuroscience, 2023-03-14;17(0):1160243. 2023-03-14 [PMID: 36998729] (Rat) Rat
SK Tirunavall, M Kuncha, R Sistla, SB Andugulapa Targeting TGF-beta/periostin signaling by sesamol ameliorates pulmonary fibrosis and improves lung function and survival The Journal of nutritional biochemistry, 2023-03-21;0(0):109294. 2023-03-21 [PMID: 36948431] (Rat) Rat
Show All 99 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for IL-6 (DY506). (Showing 1 - 1 of 1 FAQs).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

Additional IL-6 Products

Blogs on IL-6. Showing 1-10 of 12 blog posts - Show all blog posts.


  Read full blog post.


  Read full blog post.

Rest in Peace: Is the Receptor Interacting Protein (RIP) Kinase-3 (RIPK3) a Protector or Offender?
By Jamshed Arslan, Pharm. D., PhD. Receptor interacting protein kinases (RIPKs) in necroptosisDeath is perhaps inevitable. Cell death can be programed and immunologically silent (apoptosis), unprogrammed and inflamm...  Read full blog post.


  Read full blog post.

Metabolic Syndrome: Symptoms and associated disease states
By Jamshed Arslan, Pharm. D., PhD. What is metabolic syndrome?It was 1988 when, after decades of research, Dr. GM Reaven    of the Stanford University, CA, explained the relationship between four diseases:...  Read full blog post.

Increased wild type FUS levels in ALS patients lead to a toxic microenvironment and motor neuron neurodegeneration
By Michalina Hanzel, PhDFUS mutations in Amyotrophic Lateral SclerosisFused in sarcoma (FUS) is a ribonucleoprotein that continuously shuttles between the nucleus and the cytoplasm to regulate pre-mRNA splicing, mRN...  Read full blog post.

The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins.  The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein ...  Read full blog post.

The use of a GFP antibody for research applications in transgenic C. elegans, GFP tagged yeast and porcine model
GFP, or green fluorescent protein, is a chemiluminescent protein derived from Aequorea jellyfish that was first discovered by Osamu Shimomura.  It was soon after established that the emission spectra of GFP was right around 509nm, or the ultraviol...  Read full blog post.

VEGF: Vascular endothelial growth factor
VEGF is homodimeric, disulfide-linked glycoprotein cytokine that serves as the ligand for FLT1 (VEGFR-1 receptor) and FLK1 (VEGFR-2 receptor) tyrosine kinases. It is a key modulator of physiological angiogenesis, vasculogenesis, and endothelial cell g...  Read full blog post.

TLR2 - I can recognize many foreign pathogens!
TLR2 is a member of the broad family of Toll-like receptors (TLR) that play an important role in pathogen recognition and innate immunity. TLRs, like other pattern recognition receptors (PRRs), recognize endogenous ligands released during cell or tiss...  Read full blog post.

Showing 1-10 of 12 blog posts - Show all blog posts.
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Bioinformatics

Gene Symbol Il6