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RASD2 Antibody - BSA Free

Images

 
Western Blot: RASD2 Antibody [NBP1-77313] - Rat colon tissue lysate with RASD2 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: RASD2 Antibody - BSA Free [NBP1-77313] - Immunofluorescence of RASD2 in Human Colon cells with RASD2 antibody at 20 u/mL.
Immunohistochemistry: RASD2 Antibody - BSA Free [NBP1-77313] - Immunohistochemistry of RASD2 in human colon tissue with RASD2 antibody at 2.5 u/mL.

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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RASD2 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide near the amino terminus of the human TEM2. The immunogen is located within amino acids 20 - 70 of TEM2. Amino Acid Squence: FLNGRFEDQYTPTIED
Specificity
TEM2 antibody may cross-react with the closely related protein RASD1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
RASD2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
Control Peptide
RASD2 Peptide (NBP1-77313PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for RASD2 Antibody - BSA Free

  • GTP-binding protein Rhes
  • MGC:4834
  • RASD family, member 2
  • Rhes
  • TEM2Ras homolog enriched in striatum
  • Tumor endothelial marker 2

Background

Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. TEM2 antibody may cross-react with the closely related protein RASD1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol RASD2
Uniprot