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RanGAP1 Antibody (OTI1B4) [PE]

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Product Details

Summary
Reactivity Hu, Mu, Rt, CaSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, CyTOF-ready
Clone
OTI1B4
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 350
NBP2-73797AF350
Alexa Fluor 405
NBP2-73797AF405
Alexa Fluor 488
NBP2-73797AF488
Alexa Fluor 532
NBP2-73797AF532
Alexa Fluor 594
NBP2-73797AF594
Alexa Fluor 647
NBP2-73797AF647
Alexa Fluor 700
NBP2-73797AF700
Alexa Fluor 750
NBP2-73797AF750
Allophycocyanin
NBP2-73797APC
Biotin
NBP2-73797B
CoraFluor 1
NBP2-73797CL1
DyLight 350
NBP2-73797UV
DyLight 405
NBP2-73797V
DyLight 488
NBP2-73797G
DyLight 550
NBP2-73797R
DyLight 594
NBP2-73797DL594
DyLight 650
NBP2-73797C
DyLight 680
NBP2-73797FR
DyLight 755
NBP2-73797IR
FITC
NBP2-73797F
HRP
NBP2-73797H
Janelia Fluor 525
NBP2-73797JF525
Janelia Fluor 549
NBP2-73797JF549
Janelia Fluor 585
NBP2-73797JF585
Janelia Fluor 635
NBP2-73797JF635
Janelia Fluor 646
NBP2-73797JF646
Janelia Fluor 669
NBP2-73797JF669
PerCP
NBP2-73797PCP
Unconjugated
NBP2-02623
mFluor Violet 450 SE
NBP2-73797MFV450
mFluor Violet 500 SE
NBP2-73797MFV500
mFluor Violet 610 SE
NBP2-73797MFV610
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NBP2-02623
Azide and BSA Free
NBP2-73797
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RanGAP1 Antibody (OTI1B4) [PE] Summary

Immunogen
Full length recombinant protein of human RanGAP1 (NP_002874) produced in HEK293T cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
RANGAP1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for RanGAP1 Antibody (OTI1B4) [PE]

  • Fug1
  • KIAA1835Fug1
  • MGC20266
  • Ran GTPase activating protein 1
  • ran GTPase-activating protein 1
  • RanGAP1
  • SD
  • segregation distorter homolog (Drosophila)
  • segregation distorter homolog
  • segregation distortion

Background

RanGAP1, is a homodimeric 65-kD polypeptide that specifically induces the GTPase activity of RAN, but not of RAS by over 1,000-fold. RanGAP1 is the immediate antagonist of RCC1, a regulator molecule that keeps RAN in the active, GTP-bound state. The RANGAP1 gene encodes a 587-amino acid polypeptide. The sequence is unrelated to that of GTPase activators for other RAS-related proteins, but is 88% identical to Fug1, the murine homolog of yeast Rna1p. RanGAP1 and RCC1 control RAN-dependent transport between the nucleus and cytoplasm. RanGAP1 is a key regulator of the RAN GTP/GDP cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol RANGAP1