Quantikine Immunoassay Control Set 1063 for Human ST2/IL-33R Summary
Additional Information |
For use with catalog number DST200 |
Source |
N/A |
Inter-Assay |
See PDF Datasheet for details |
Intra-Assay |
See PDF Datasheet for details |
Spike Recovery |
See PDF Datasheet for details |
Sample Volume |
See PDF Datasheet for details |
Gene |
IL1RL1 |
Applications/Dilutions
Packaging, Storage & Formulations
Storage |
Store the unopened product at 2 - 8 °C. Do not use past expiration date. |
Notes
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for Quantikine Immunoassay Control Set 1063 for Human ST2/IL-33R
Background
ST2, also known as IL-1 R4, is a component of the receptor for the proinflammatory cytokine Interleukin-33. The IL-33 receptor additionally includes IL-1 RAcp which also associates with IL-1 RI and IL-1 R rp2/IL-1 R6. A soluble form of ST2 functions as a decoy receptor. IL-33 promotes Th2-biased immune responses, resulting in eosinophilia, mast cell activation, and allergic inflammation. In addition, IL-33 enhances inflammation-associated hypernociception and protects from atherosclerosis and cardiac myocyte hypertrophy. Soluble ST2 is elevated in the serum under inflammatory conditions including allergic asthma, sepsis, trauma, dengue fever, pulmonary disease, and lupus. It is also associated aortic stenosis, congestive cardiomyopathy, and risk of cardiovascular heart failure and death.
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