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Pyruvate Dehydrogenase E2 Antibody [Janelia Fluor® 585]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IHC, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Janelia Fluor 585

Order Details

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Pyruvate Dehydrogenase E2 Antibody [Janelia Fluor® 585] Summary

Immunogen
Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human Pyruvate Dehydrogenase E2.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
DLAT
Purity
Antigen and protein A Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Immunoprecipitation
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Antigen and protein A Affinity-purified

Notes



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Pyruvate Dehydrogenase E2 Antibody [Janelia Fluor® 585]

  • 70 kDa mitochondrial autoantigen of primary biliary cirrhosis
  • dihydrolipoamide S-acetyltransferase
  • DLTA
  • E2 component of pyruvate dehydrogenase complex
  • EC 2.3.1
  • M2 antigen complex 70 kDa subunit
  • PBC
  • PDC-E2EC 2.3.1.12
  • PDCE2mitochondrial

Background

The DLAT gene encodes dihydrolipoamide acetyltransferase (EC 2.3.1.12), the E2 subunit of the mammalian pyruvate dehydrogenase complex (PDC; EC 1.2.4.1) of the inner mitochondrial membrane. Patients with primary biliary cirrhosis (PBC; MIM 109720) show autoantibodies to DLAT.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol DLAT