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PTP pi/PTPRU Antibody (PTPRU/7616) [Alexa Fluor® 405]

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications IHC
Clone
PTPRU/7616
Clonality
Monoclonal
Host
Mouse
Conjugate
Alexa Fluor 405

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PTP pi/PTPRU Antibody (PTPRU/7616) [Alexa Fluor® 405] Summary

Immunogen
Recombinant fragment (around aa1-200) of human PTP pi/PTPRU protein (exact sequence is proprietary)
Localization
Cell junction. Cell membrane. Single-pass type I membrane protein.
Isotype
IgG2 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PTPRU
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes



Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PTP pi/PTPRU Antibody (PTPRU/7616) [Alexa Fluor® 405]

  • FMI
  • GLEPP1
  • hPTP-J
  • pancreatic carcinoma phosphatase 2
  • PCP2
  • PCP-2
  • pi R-PTP-Psi
  • protein tyrosine phosphatase J
  • protein tyrosine phosphatase, receptor type, U
  • protein-tyrosine phosphatase J
  • protein-tyrosine phosphatase pi
  • PTP pi
  • PTP
  • PTP-J
  • PTP-PI
  • PTPPSI
  • PTPRO
  • PTP-RO
  • PTPRU
  • Receptor protein tyrosine phosphatase hPTP-J
  • R-PTP-PSI
  • R-PTP-U

Background

The protein encoded by the PTPRU gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracellular catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP (MAM) domain, Ig-like and fibronectin type III-like repeats. This PTP was thought to play roles in cell-cell recognition and adhesion. Studies of the similar gene in mice suggested the role of this PTP in early neural development. The expression of this gene was reported to be regulated by phorbol myristate acetate (PMA) or calcium ionophore in Jurkat T lymphoma cells. Three alternatively spliced transcript variants, which encode distinct proteins, have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PTPRU