Presenilin-1 Antibody [Biotin] - C-terminal Fragment

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Presenilin-1 (PS-1) and Presenilin-2 (PS-2) are integral membrane proteins that contain multiple transmembrane domains. Both are predominantly located within the endoplasmic reticulum (ER) and early Golgi apparatus. They are primarily expressed in neurons and are ubiquitously expressed in the brain. PS-1 and PS-2 are proteolytically cleaved to generate an N-terminal fragment (NTF) and a C-terminal fragment (CTF). Mutations in the gene for Presenilin may play an important role in the pathology of Alzheimer's disease.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: ICC.

Showing Publication 1 - 1 of 1.

Publication using BAF166	Applications	Species
Thomas AV, Herl L, Spoelgen R, Hiltunen M, Jones PB, Tanzi RE, Hyman BT, Berezovska O Interaction between presenilin 1 and ubiquilin 1 as detected by fluorescence lifetime imaging microscopy and a high-throughput fluorescent plate reader. J. Biol. Chem., 2006-06-30;281(36):26400-7. 2006-06-30 [PMID: 16815845] (ICC, Human)	ICC	Human

Array BAF166

• Presenilin-1 Antibodies
• Presenilin-1 ELISA Kits
• Presenilin-1 Lysate
• Presenilin-1 Proteins