PPOX Antibody (2F10)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Showing Publications 1 - 3 of 3.

Publications using H00005498-M01	Applications	Species
Yang DF, Chen JH, Chiang CP et al. Improve efficacy of topical ALA-PDT by calcipotriol through up-regulation of coproporphyrinogen oxidase. Photodiagnosis Photodyn Ther. 2014-05-02 [PMID: 24907534]
Yang DF, Lee JW, Chen HM et al. Methotrexate enhances 5-aminolevulinic acid-mediated photodynamic therapy-induced killing of human SCC4 cells by upregulation of coproporphyrinogen oxidase. J Formos Med Assoc. 2014-01-29 [PMID: 24485831]
Crooks DR, Ghosh MC, Haller RG et al. Posttranslational stability of the heme biosynthetic enzyme ferrochelatase is dependent on iron availability and intact iron-sulfur cluster assembly machinery. Blood 115(4):860-9. 2010-01-28 [PMID: 19965627]

Array H00005498-M01

• PPOX Antibodies
• PPOX Lysates
• PPOX Proteins